 Acetyl Coenzyme A
"Acetyl Coenzyme A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
| Descriptor ID |
D000105
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| MeSH Number(s) |
D03.438.759.646.138.382.300.020 D08.211.211.300.075 D13.695.667.138.382.300.020 D13.695.827.068.382.300.020
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Acetyl Coenzyme A".
Below are MeSH descriptors whose meaning is more specific than "Acetyl Coenzyme A".
This graph shows the total number of publications written about "Acetyl Coenzyme A" by people in this website by year, and whether "Acetyl Coenzyme A" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 | | 2004 | 1 | 1 | 2 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acetyl Coenzyme A" by people in Profiles.
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Lee JV, Berry CT, Kim K, Sen P, Kim T, Carrer A, Trefely S, Zhao S, Fernandez S, Barney LE, Schwartz AD, Peyton SR, Snyder NW, Berger SL, Freedman BD, Wellen KE. Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+-NFAT signaling. Genes Dev. 2018 04 01; 32(7-8):497-511.
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Perry RJ, Camporez JP, Kursawe R, Titchenell PM, Zhang D, Perry CJ, Jurczak MJ, Abudukadier A, Han MS, Zhang XM, Ruan HB, Yang X, Caprio S, Kaech SM, Sul HS, Birnbaum MJ, Davis RJ, Cline GW, Petersen KF, Shulman GI. Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes. Cell. 2015 Feb 12; 160(4):745-58.
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Baek SH, Li AH, Sassetti CM. Metabolic regulation of mycobacterial growth and antibiotic sensitivity. PLoS Biol. 2011 May; 9(5):e1001065.
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Bouzakri K, Austin R, Rune A, Lassman ME, Garcia-Roves PM, Berger JP, Krook A, Chibalin AV, Zhang BB, Zierath JR. Malonyl CoenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle. Diabetes. 2008 Jun; 57(6):1508-16.
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Bian F, Kasumov T, Jobbins KA, Minkler PE, Anderson VE, Kerner J, Hoppel CL, Brunengraber H. Competition between acetate and oleate for the formation of malonyl-CoA and mitochondrial acetyl-CoA in the perfused rat heart. J Mol Cell Cardiol. 2006 Nov; 41(5):868-75.
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Kasumov T, Adams JE, Bian F, David F, Thomas KR, Jobbins KA, Minkler PE, Hoppel CL, Brunengraber H. Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver. Biochem J. 2005 Jul 15; 389(Pt 2):397-401.
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Bian F, Kasumov T, Thomas KR, Jobbins KA, David F, Minkler PE, Hoppel CL, Brunengraber H. Peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13C labeling of malonyl-CoA and the acetyl moiety of citrate. J Biol Chem. 2005 Mar 11; 280(10):9265-71.
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Reszko AE, Kasumov T, David F, Thomas KR, Jobbins KA, Cheng JF, Lopaschuk GD, Dyck JR, Diaz M, Des Rosiers C, Stanley WC, Brunengraber H. Regulation of malonyl-CoA concentration and turnover in the normal heart. J Biol Chem. 2004 Aug 13; 279(33):34298-301.
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Langer MR, Fry CJ, Peterson CL, Denu JM. Modulating acetyl-CoA binding in the GCN5 family of histone acetyltransferases. J Biol Chem. 2002 Jul 26; 277(30):27337-44.
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