Acetyl Coenzyme A

"Acetyl Coenzyme A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.

Descriptor ID	D000105
MeSH Number(s)	D03.633.100.759.646.138.382.300.020 D08.211.211.300.075 D13.695.667.138.382.300.020 D13.695.827.068.382.300.020
Concept/Terms	Acetyl Coenzyme A Acetyl Coenzyme A Coenzyme A, Acetyl Acetyl-CoA Acetyl CoA CoA, Acetyl

Below are MeSH descriptors whose meaning is more general than "Acetyl Coenzyme A".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Purines [D03.633.100.759]
Purine Nucleotides [D03.633.100.759.646]
Adenine Nucleotides [D03.633.100.759.646.138]
Coenzyme A [D03.633.100.759.646.138.382]
Acyl Coenzyme A [D03.633.100.759.646.138.382.300]
Acetyl Coenzyme A [D03.633.100.759.646.138.382.300.020]
Enzymes and Coenzymes [D08]
Coenzymes [D08.211]
Coenzyme A [D08.211.211]
Acyl Coenzyme A [D08.211.211.300]
Acetyl Coenzyme A [D08.211.211.300.075]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleotides [D13.695]
Purine Nucleotides [D13.695.667]
Adenine Nucleotides [D13.695.667.138]
Coenzyme A [D13.695.667.138.382]
Acyl Coenzyme A [D13.695.667.138.382.300]
Acetyl Coenzyme A [D13.695.667.138.382.300.020]
Ribonucleotides [D13.695.827]
Adenine Nucleotides [D13.695.827.068]
Coenzyme A [D13.695.827.068.382]
Acyl Coenzyme A [D13.695.827.068.382.300]
Acetyl Coenzyme A [D13.695.827.068.382.300.020]

Below are MeSH descriptors whose meaning is related to "Acetyl Coenzyme A".

Below are MeSH descriptors whose meaning is more specific than "Acetyl Coenzyme A".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Acetyl Coenzyme A" by people in this website by year, and whether "Acetyl Coenzyme A" was a major or minor topic of these publications.

Bar chart showing 16 publications over 14 distinct years, with a maximum of 2 publications in 2004 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2004	1	1	2
2005	1	0	1
2006	1	0	1
2008	0	1	1
2011	0	1	1
2012	0	1	1
2015	1	0	1
2017	0	1	1
2018	1	0	1
2019	1	0	1
2020	1	0	1
2022	0	1	1
2023	1	1	2

Below are the most recent publications written about "Acetyl Coenzyme A" by people in Profiles.

Guilherme A, Rowland LA, Wetoska N, Tsagkaraki E, Santos KB, Bedard AH, Henriques F, Kelly M, Munroe S, Pedersen DJ, Ilkayeva OR, Koves TR, Tauer L, Pan M, Han X, Kim JK, Newgard CB, Muoio DM, Czech MP. Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program. Cell Rep. 2023 05 30; 42(5):112488.

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Guertin DA, Wellen KE. Acetyl-CoA metabolism in cancer. Nat Rev Cancer. 2023 03; 23(3):156-172.

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Yenilmez B, Kelly M, Zhang GF, Wetoska N, Ilkayeva OR, Min K, Rowland L, DiMarzio C, He W, Raymond N, Lifshitz L, Pan M, Han X, Xie J, Friedline RH, Kim JK, Gao G, Herman MA, Newgard CB, Czech MP. Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice. J Biol Chem. 2022 10; 298(10):102401.

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Miao R, Xie H, Liu X, Lindberg P, Lindblad P. Current processes and future challenges of photoautotrophic production of acetyl-CoA-derived solar fuels and chemicals in cyanobacteria. Curr Opin Chem Biol. 2020 12; 59:69-76.

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Lauterbach MA, Hanke JE, Serefidou M, Mangan MSJ, Kolbe CC, Hess T, Rothe M, Kaiser R, Hoss F, Gehlen J, Engels G, Kreutzenbeck M, Schmidt SV, Christ A, Imhof A, Hiller K, Latz E. Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase. Immunity. 2019 12 17; 51(6):997-1011.e7.

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Lee JV, Berry CT, Kim K, Sen P, Kim T, Carrer A, Trefely S, Zhao S, Fernandez S, Barney LE, Schwartz AD, Peyton SR, Snyder NW, Berger SL, Freedman BD, Wellen KE. Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+-NFAT signaling. Genes Dev. 2018 04 01; 32(7-8):497-511.

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Foyn H, Thompson PR, Arnesen T. DTNB-Based Quantification of In Vitro Enzymatic N-Terminal Acetyltransferase Activity. Methods Mol Biol. 2017; 1574:9-15.

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Perry RJ, Camporez JG, Kursawe R, Titchenell PM, Zhang D, Perry CJ, Jurczak MJ, Abudukadier A, Han MS, Zhang XM, Ruan HB, Yang X, Caprio S, Kaech SM, Sul HS, Birnbaum MJ, Davis RJ, Cline GW, Petersen KF, Shulman GI. Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes. Cell. 2015 Feb 12; 160(4):745-758.

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Evjenth RH, Brenner AK, Thompson PR, Arnesen T, Fr?ystein N?, Lillehaug JR. Human protein N-terminal acetyltransferase hNaa50p (hNAT5/hSAN) follows ordered sequential catalytic mechanism: combined kinetic and NMR study. J Biol Chem. 2012 Mar 23; 287(13):10081-10088.

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Baek SH, Li AH, Sassetti CM. Metabolic regulation of mycobacterial growth and antibiotic sensitivity. PLoS Biol. 2011 May; 9(5):e1001065.

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