"Conotoxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptide neurotoxins from the marine fish-hunting snails of the genus CONUS. They contain 13 to 29 amino acids which are strongly basic and are highly cross-linked by disulfide bonds. There are three types of conotoxins, omega-, alpha-, and mu-. OMEGA-CONOTOXINS inhibit voltage-activated entry of calcium into the presynaptic membrane and therefore the release of ACETYLCHOLINE. Alpha-conotoxins inhibit the postsynaptic acetylcholine receptor. Mu-conotoxins prevent the generation of muscle action potentials. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
| Descriptor ID |
D020916
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| MeSH Number(s) |
D20.888.590.162 D23.946.580.590.162 D23.946.833.590.162
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Conotoxins".
Below are MeSH descriptors whose meaning is more specific than "Conotoxins".
This graph shows the total number of publications written about "Conotoxins" by people in this website by year, and whether "Conotoxins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Conotoxins" by people in Profiles.
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Ram?rez D, Gonzalez W, Fissore RA, Carvacho I. Conotoxins as Tools to Understand the Physiological Function of Voltage-Gated Calcium (CaV) Channels. Mar Drugs. 2017 Oct 13; 15(10).
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Rittenhouse AR. Novel coupling is painless. J Gen Physiol. 2014 Apr; 143(4):443-7.
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Zafaralla GC, Ramilo C, Gray WR, Karlstrom R, Olivera BM, Cruz LJ. Phylogenetic specificity of cholinergic ligands: alpha-conotoxin SI. Biochemistry. 1988 Sep 06; 27(18):7102-5.