Minor Histocompatibility Antigens

"Minor Histocompatibility Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Allelic alloantigens often responsible for weak graft rejection in cases when (major) histocompatibility has been established by standard tests. In the mouse they are coded by more than 500 genes at up to 30 minor histocompatibility loci. The most well-known minor histocompatibility antigen in mammals is the H-Y antigen.

Descriptor ID	D015778
MeSH Number(s)	D23.050.301.500.600 D23.050.705.552.600
Concept/Terms	Minor Histocompatibility Antigens Minor Histocompatibility Antigens Histocompatibility Antigens, Minor Minor Histocompatibility Peptides Histocompatibility Peptides, Minor

Below are MeSH descriptors whose meaning is more general than "Minor Histocompatibility Antigens".

Chemicals and Drugs [D]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Surface [D23.050.301]
Histocompatibility Antigens [D23.050.301.500]
Minor Histocompatibility Antigens [D23.050.301.500.600]
Isoantigens [D23.050.705]
Histocompatibility Antigens [D23.050.705.552]
Minor Histocompatibility Antigens [D23.050.705.552.600]

Below are MeSH descriptors whose meaning is related to "Minor Histocompatibility Antigens".

Below are MeSH descriptors whose meaning is more specific than "Minor Histocompatibility Antigens".

Minor Histocompatibility Antigens
Antigens, CD19
Cathepsin H
Focal Adhesion Kinase 2
H-Y Antigen
Receptor, ErbB-2
Receptors, Purinergic P2X5
Reduced Folate Carrier Protein
rho Guanine Nucleotide Dissociation Inhibitor beta
Thymidine Phosphorylase
WNK Lysine-Deficient Protein Kinase 1

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Minor Histocompatibility Antigens" by people in this website by year, and whether "Minor Histocompatibility Antigens" was a major or minor topic of these publications.

Bar chart showing 27 publications over 18 distinct years, with a maximum of 3 publications in 2010 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2000	0	1	1
2002	0	1	1
2005	0	1	1
2006	0	1	1
2007	0	1	1
2008	0	1	1
2009	0	2	2
2010	0	3	3
2011	0	2	2
2013	0	2	2
2014	0	1	1
2017	1	0	1
2018	1	1	2
2019	1	2	3
2020	1	1	2
2021	1	0	1
2022	0	1	1

Below are the most recent publications written about "Minor Histocompatibility Antigens" by people in Profiles.

Arya R, Maben Z, Rane D, Ali A, Stern LJ. Phenylsulfamoyl Benzoic Acid Inhibitor of ERAP2 with a Novel Mode of Inhibition. ACS Chem Biol. 2022 07 15; 17(7):1756-1768.

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Maben Z, Arya R, Georgiadis D, Stratikos E, Stern LJ. Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism. Nat Commun. 2021 09 06; 12(1):5302.

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Colbert JD, Rock KL. How a tailor achieves the perfect fit. J Biol Chem. 2020 05 22; 295(21):7211-7212.

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Mavridis G, Arya R, Domnick A, Zoidakis J, Makridakis M, Vlahou A, Mpakali A, Lelis A, Georgiadis D, Tamp? R, Papakyriakou A, Stern LJ, Stratikos E. A systematic re-examination of processing of MHCI-bound antigenic peptide precursors by endoplasmic reticulum aminopeptidase 1. J Biol Chem. 2020 05 22; 295(21):7193-7210.

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Maben Z, Arya R, Rane D, An WF, Metkar S, Hickey M, Bender S, Ali A, Nguyen TT, Evnouchidou I, Schilling R, Stratikos E, Golden J, Stern LJ. Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1. J Med Chem. 2020 01 09; 63(1):103-121.

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Koumantou D, Barnea E, Martin-Esteban A, Maben Z, Papakyriakou A, Mpakali A, Kokkala P, Pratsinis H, Georgiadis D, Stern LJ, Admon A, Stratikos E. Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1). Cancer Immunol Immunother. 2019 Aug; 68(8):1245-1261.

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Wong EB, Gold MC, Meermeier EW, Xulu BZ, Khuzwayo S, Sullivan ZA, Mahyari E, Rogers Z, Kl?verpris H, Sharma PK, Worley AH, Lalloo U, Baijnath P, Ambaram A, Naidoo L, Suleman M, Madansein R, McLaren JE, Ladell K, Miners KL, Price DA, Behar SM, Nielsen M, Kasprowicz VO, Leslie A, Bishai WR, Ndung'u T, Lewinsohn DM. TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis. Commun Biol. 2019; 2:203.

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Hou S, Silvas TV, Leidner F, Nalivaika EA, Matsuo H, Kurt Yilmaz N, Schiffer CA. Structural Analysis of the Active Site and DNA Binding of Human Cytidine Deaminase APOBEC3B. J Chem Theory Comput. 2019 Jan 08; 15(1):637-647.

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McBrayer SK, Mayers JR, DiNatale GJ, Shi DD, Khanal J, Chakraborty AA, Sarosiek KA, Briggs KJ, Robbins AK, Sewastianik T, Shareef SJ, Olenchock BA, Parker SJ, Tateishi K, Spinelli JB, Islam M, Haigis MC, Looper RE, Ligon KL, Bernstein BE, Carrasco RD, Cahill DP, Asara JM, Metallo CM, Yennawar NH, Vander Heiden MG, Kaelin WG. Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma. Cell. 2018 09 20; 175(1):101-116.e25.

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Stamogiannos A, Maben Z, Papakyriakou A, Mpakali A, Kokkala P, Georgiadis D, Stern LJ, Stratikos E. Critical Role of Interdomain Interactions in the Conformational Change and Catalytic Mechanism of Endoplasmic Reticulum Aminopeptidase 1. Biochemistry. 2017 03 14; 56(10):1546-1558.

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