Dinucleoside Phosphates

"Dinucleoside Phosphates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A group of compounds which consist of a nucleotide molecule to which an additional nucleoside is attached through the phosphate molecule(s). The nucleotide can contain any number of phosphates.

Descriptor ID	D015226
MeSH Number(s)	D13.695.250
Concept/Terms	Dinucleoside Phosphates Dinucleoside Phosphates Phosphates, Dinucleoside Dinucleoside Diphosphates Dinucleoside Diphosphates Diphosphates, Dinucleoside Dinucleoside Monophosphates Dinucleoside Monophosphates Monophosphates, Dinucleoside Dinucleoside Oligophosphates Dinucleoside Oligophosphates Oligophosphates, Dinucleoside Bis(5'-Nucleosidyl)Oligophosphates Bis(5'-Nucleosidyl)Phosphates Bis(5'-Nucleosidyl)Phosphates Dinucleoside Polyphosphates Dinucleoside Polyphosphates Polyphosphates, Dinucleoside Dinucleoside Tetraphosphates Dinucleoside Tetraphosphates Tetraphosphates, Dinucleoside Bis(5'-Nucleosidyl)Tetraphosphate Dinucleoside Triphosphates Dinucleoside Triphosphates Triphosphates, Dinucleoside Deoxydinucleoside Phosphates Deoxydinucleoside Phosphates Phosphates, Deoxydinucleoside

Below are MeSH descriptors whose meaning is more general than "Dinucleoside Phosphates".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleotides [D13.695]
Dinucleoside Phosphates [D13.695.250]

Below are MeSH descriptors whose meaning is related to "Dinucleoside Phosphates".

Below are MeSH descriptors whose meaning is more specific than "Dinucleoside Phosphates".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Dinucleoside Phosphates" by people in this website by year, and whether "Dinucleoside Phosphates" was a major or minor topic of these publications.

Bar chart showing 34 publications over 20 distinct years, with a maximum of 5 publications in 1998

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	2	0	2
1996	3	1	4
1997	1	0	1
1998	4	1	5
1999	3	0	3
2000	1	0	1
2001	1	0	1
2002	1	0	1
2003	1	0	1
2005	0	1	1
2008	0	3	3
2009	1	0	1
2011	0	1	1
2012	1	0	1
2013	1	0	1
2014	1	0	1
2015	0	1	1
2016	2	0	2
2018	1	0	1
2020	2	0	2

Below are the most recent publications written about "Dinucleoside Phosphates" by people in Profiles.

Chatterjee P, Lee J, Nip L, Koseki SRT, Tysinger E, Sontheimer EJ, Jacobson JM, Jakimo N. A Cas9 with PAM recognition for adenine dinucleotides. Nat Commun. 2020 05 18; 11(1):2474.

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Wooten AK, Shenoy AT, Arafa EI, Akiyama H, Martin IMC, Jones MR, Quinton LJ, Gummuluru S, Bai G, Mizgerd JP. Unique Roles for Streptococcus pneumoniae Phosphodiesterase 2 in Cyclic di-AMP Catabolism and Macrophage Responses. Front Immunol. 2020; 11:554.

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Smolensky Koganov E, Michelson AD, Yanachkov IB, Yanachkova MI, Wright GE, Przyklenk K, Frelinger AL. GLS-409, an Antagonist of Both P2Y1 and P2Y12, Potently Inhibits Canine Coronary Artery Thrombosis and Reversibly Inhibits Human Platelet Activation. Sci Rep. 2018 09 28; 8(1):14529.

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Andrade WA, Firon A, Schmidt T, Hornung V, Fitzgerald KA, Kurt-Jones EA, Trieu-Cuot P, Golenbock DT, Kaminski PA. Group B Streptococcus Degrades Cyclic-di-AMP to Modulate STING-Dependent Type I Interferon Production. Cell Host Microbe. 2016 Jul 13; 20(1):49-59.

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Gremmel T, Yanachkov IB, Yanachkova MI, Wright GE, Wider J, Undyala VV, Michelson AD, Frelinger AL, Przyklenk K. Synergistic Inhibition of Both P2Y1 and P2Y12 Adenosine Diphosphate Receptors As Novel Approach to Rapidly Attenuate Platelet-Mediated Thrombosis. Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3):501-9.

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Yanachkov IB, Chang H, Yanachkova MI, Dix EJ, Berny-Lang MA, Gremmel T, Michelson AD, Wright GE, Frelinger AL. New highly active antiplatelet agents with dual specificity for platelet P2Y1 and P2Y12 adenosine diphosphate receptors. Eur J Med Chem. 2016 Jan 01; 107:204-18.

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Chang H, Yanachkov IB, Dix EJ, Yanachkova M, Li Y, Barnard MR, Wright GE, Michelson AD, Frelinger AL. Antiplatelet activity, P2Y1 and P2Y12 inhibition, and metabolism in plasma of stereoisomers of diadenosine 5',5'?-P? ,P4-dithio-P?,P?-chloromethylenetetraphosphate. PLoS One. 2014; 9(4):e94780.

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Abdul-Sater AA, Tattoli I, Jin L, Grajkowski A, Levi A, Koller BH, Allen IC, Beaucage SL, Fitzgerald KA, Ting JP, Cambier JC, Girardin SE, Schindler C. Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome. EMBO Rep. 2013 Oct; 14(10):900-6.

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Chang H, Yanachkov IB, Dix EJ, Li YF, Barnard MR, Wright GE, Michelson AD, Frelinger AL. Modified diadenosine tetraphosphates with dual specificity for P2Y1 and P2Y12 are potent antagonists of ADP-induced platelet activation. J Thromb Haemost. 2012 Dec; 10(12):2573-80.

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Shearstone JR, Pop R, Bock C, Boyle P, Meissner A, Socolovsky M. Global DNA demethylation during mouse erythropoiesis in vivo. Science. 2011 Nov 11; 334(6057):799-802.

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