Translation products of a fusion gene derived from CHROMOSOMAL TRANSLOCATION of C-ABL GENES to the genetic locus of the breakpoint cluster region gene on chromosome 22. Several different variants of the bcr-abl fusion proteins occur depending upon the precise location of the chromosomal breakpoint. These variants can be associated with distinct subtypes of leukemias such as PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; and NEUTROPHILIC LEUKEMIA, CHRONIC.

Descriptor ID	D016044
MeSH Number(s)	D08.811.913.696.620.682.725.500.500 D12.776.602.500.500.100 D12.776.624.664.500.100 D12.776.624.664.700.171.500
Concept/Terms	Fusion Proteins, bcr-abl Fusion Proteins, bcr-abl Fusion Proteins, bcr abl bcr-abl Fusion Proteins bcr abl Fusion Proteins Bcr-Abl Tyrosine Kinase Bcr Abl Tyrosine Kinase Kinase, Bcr-Abl Tyrosine Tyrosine Kinase, Bcr-Abl Oncogene Protein p190(bcr-abl) Oncogene Protein p190(bcr-abl) p190(bcr-abl) Fusion Proteins Oncogene Protein p230(bcr-abl) Oncogene Protein p230(bcr-abl) p230(bcr-abl) Fusion Proteins Oncogene Protein p185(bcr-abl) Oncogene Protein p185(bcr-abl) p185(bcr-abl) Fusion Proteins Oncogene Protein p210(bcr-abl) Oncogene Protein p210(bcr-abl) p210(bcr-abl) Fusion Proteins

Below are MeSH descriptors whose meaning is more general than "Fusion Proteins, bcr-abl".

Below are MeSH descriptors whose meaning is related to "Fusion Proteins, bcr-abl".

Below are MeSH descriptors whose meaning is more specific than "Fusion Proteins, bcr-abl".