"Tachykinins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of biologically active peptides sharing a common conserved C-terminal sequence, -Phe-X-Gly-Leu-Met-NH2, where X is either an aromatic or a branched aliphatic amino acid. Members of this family have been found in mammals, amphibians, and mollusks. Tachykinins have diverse pharmacological actions in the central nervous system and the cardiovascular, genitourinary, respiratory, and gastrointestinal systems, as well as in glandular tissues. This diversity of activity is due to the existence of three or more subtypes of tachykinin receptors.
| Descriptor ID |
D015320
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| MeSH Number(s) |
D12.644.276.812.900 D12.644.400.800 D12.644.456.800 D12.776.467.812.900 D12.776.631.650.800 D23.469.050.375.850 D23.529.812.900
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tachykinins".
Below are MeSH descriptors whose meaning is more specific than "Tachykinins".
This graph shows the total number of publications written about "Tachykinins" by people in this website by year, and whether "Tachykinins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tachykinins" by people in Profiles.
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Im SH, Takle K, Jo J, Babcock DT, Ma Z, Xiang Y, Galko MJ. Tachykinin acts upstream of autocrine Hedgehog signaling during nociceptive sensitization in Drosophila. Elife. 2015 Nov 17; 4:e10735.
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Amcheslavsky A, Song W, Li Q, Nie Y, Bragatto I, Ferrandon D, Perrimon N, Ip YT. Enteroendocrine cells support intestinal stem-cell-mediated homeostasis in Drosophila. Cell Rep. 2014 Oct 09; 9(1):32-39.
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Gill JC, Navarro VM, Kwong C, Noel SD, Martin C, Xu S, Clifton DK, Carroll RS, Steiner RA, Kaiser UB. Increased neurokinin B (Tac2) expression in the mouse arcuate nucleus is an early marker of pubertal onset with differential sensitivity to sex steroid-negative feedback than Kiss1. Endocrinology. 2012 Oct; 153(10):4883-93.
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Bera MM, Lu B, Martin TR, Cui S, Rhein LM, Gerard C, Gerard NP. Th17 cytokines are critical for respiratory syncytial virus-associated airway hyperreponsiveness through regulation by complement C3a and tachykinins. J Immunol. 2011 Oct 15; 187(8):4245-55.
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Patel N, Klassert TE, Greco SJ, Patel SA, Munoz JL, Reddy BY, Bryan M, Campbell N, Kokorina N, Sabaawy HE, Rameshwar P. Developmental regulation of TAC1 in peptidergic-induced human mesenchymal stem cells: implication for spinal cord injury in zebrafish. Stem Cells Dev. 2012 Jan 20; 21(2):308-20.
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Wang Y, Barton BA, Thim L, Nielsen PF, Conlon JM. Purification and characterization of galanin and scyliorhinin I from the hybrid sturgeon, Scaphirhynchus platorynchus x Scaphirhynchus albus (Acipenseriformes). Gen Comp Endocrinol. 1999 Jan; 113(1):38-45.
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Takebayashi T, Abraham J, Murthy GG, Lilly C, Rodger I, Shore SA. Role of tachykinins in airway responses to ozone in rats. J Appl Physiol (1985). 1998 Aug; 85(2):442-50.
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Ingenito EP, Mark L, Lilly C, Davison B. Autonomic regulation of tissue resistance in the guinea pig lung. J Appl Physiol (1985). 1995 Apr; 78(4):1382-7.
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Rizo J, Gierasch LM. Constrained peptides: models of bioactive peptides and protein substructures. Annu Rev Biochem. 1992; 61:387-418.