Neurotensin

"Neurotensin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A biologically active tridecapeptide isolated from the hypothalamus. It has been shown to induce hypotension in the rat, to stimulate contraction of guinea pig ileum and rat uterus, and to cause relaxation of rat duodenum. There is also evidence that it acts as both a peripheral and a central nervous system neurotransmitter.

Descriptor ID	D009496
MeSH Number(s)	D12.644.400.550 D12.776.631.650.550
Concept/Terms	Neurotensin Neurotensin

Below are MeSH descriptors whose meaning is more general than "Neurotensin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Neuropeptides [D12.644.400]
Neurotensin [D12.644.400.550]
Proteins [D12.776]
Nerve Tissue Proteins [D12.776.631]
Neuropeptides [D12.776.631.650]
Neurotensin [D12.776.631.650.550]

Below are MeSH descriptors whose meaning is more specific than "Neurotensin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Neurotensin" by people in this website by year, and whether "Neurotensin" was a major or minor topic of these publications.

Bar chart showing 2 publications over 1 distinct years, with a maximum of 2 publications in 1997

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	1	2

Below are the most recent publications written about "Neurotensin" by people in Profiles.

Li J, Song J, Zaytseva YY, Liu Y, Rychahou P, Jiang K, Starr ME, Kim JT, Harris JW, Yiannikouris FB, Katz WS, Nilsson PM, Orho-Melander M, Chen J, Zhu H, Fahrenholz T, Higashi RM, Gao T, Morris AJ, Cassis LA, Fan TW, Weiss HL, Dobner PR, Melander O, Jia J, Evers BM. An obligatory role for neurotensin in high-fat-diet-induced obesity. Nature. 2016 05 19; 533(7603):411-5.

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Chastain LG, Qu H, Bourke CH, Iuvone PM, Dobner PR, Nemeroff CB, Kinkead B. Striatal dopamine receptor plasticity in neurotensin deficient mice. Behav Brain Res. 2015 Mar 01; 280:160-71.

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Degolier TF, Brown DR, Duke GE, Palmer MM, Swenson JR, Carraway RE. Neurotensin and cholecystokinin contract gallbladder circular muscle in chickens. Poult Sci. 2013 Aug; 92(8):2156-62.

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DeGolier TF, Carraway RE, Duke GE. Release of avian neurotensin in response to intraluminal contents in the duodenum of chickens. Poult Sci. 2013 Feb; 92(2):418-23.

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Cochrane DE, Carraway RE, Harrington K, Laudano M, Rawlings S, Feldberg RS. HMC-1 human mast cells synthesize neurotensin (NT) precursor, secrete bioactive NT-like peptide(s) and express NT receptor NTS1. Inflamm Res. 2011 Dec; 60(12):1139-51.

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Hall FS, Centeno M, Perona MT, Adair J, Dobner PR, Uhl GR. Effects of neurotensin gene knockout in mice on the behavioral effects of cocaine. Psychopharmacology (Berl). 2012 Jan; 219(1):35-45.

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Wang X, Gulhati P, Li J, Dobner PR, Weiss H, Townsend CM, Evers BM. Characterization of promoter elements regulating the expression of the human neurotensin/neuromedin N gene. J Biol Chem. 2011 Jan 07; 286(1):542-54.

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Koon HW, Kim YS, Xu H, Kumar A, Zhao D, Karagiannides I, Dobner PR, Pothoulakis C. Neurotensin induces IL-6 secretion in mouse preadipocytes and adipose tissues during 2,4,6,-trinitrobenzensulphonic acid-induced colitis. Proc Natl Acad Sci U S A. 2009 May 26; 106(21):8766-71.

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Piliponsky AM, Chen CC, Nishimura T, Metz M, Rios EJ, Dobner PR, Wada E, Wada K, Zacharias S, Mohanasundaram UM, Faix JD, Abrink M, Pejler G, Pearl RG, Tsai M, Galli SJ. Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis. Nat Med. 2008 Apr; 14(4):392-8.

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Carraway RE, Hassan S. Neurotensin receptor binding and neurotensin-induced growth signaling in prostate cancer PC3 cells are sensitive to metabolic stress. Regul Pept. 2007 Jun 07; 141(1-3):140-53.

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