"Reactive Oxygen Species" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of SIGNAL TRANSDUCTION and GENE EXPRESSION, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.
| Descriptor ID |
D017382
|
| MeSH Number(s) |
D01.339.431 D01.650.775
|
| Concept/Terms |
Reactive Oxygen Species- Reactive Oxygen Species
- Oxygen Species, Reactive
- Active Oxygen
- Oxygen, Active
- Oxygen Radicals
- Pro-Oxidants
- Pro Oxidants
|
Below are MeSH descriptors whose meaning is more general than "Reactive Oxygen Species".
Below are MeSH descriptors whose meaning is more specific than "Reactive Oxygen Species".
This graph shows the total number of publications written about "Reactive Oxygen Species" by people in this website by year, and whether "Reactive Oxygen Species" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2002 | 3 | 1 | 4 |
| 2003 | 3 | 5 | 8 |
| 2004 | 2 | 4 | 6 |
| 2005 | 1 | 2 | 3 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 3 | 4 |
| 2008 | 1 | 3 | 4 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 10 | 11 |
| 2011 | 0 | 4 | 4 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 9 | 10 |
| 2014 | 0 | 19 | 19 |
| 2015 | 3 | 6 | 9 |
| 2016 | 5 | 8 | 13 |
| 2017 | 3 | 12 | 15 |
| 2018 | 1 | 11 | 12 |
| 2019 | 1 | 10 | 11 |
| 2020 | 1 | 4 | 5 |
| 2021 | 2 | 5 | 7 |
| 2022 | 0 | 8 | 8 |
| 2023 | 0 | 8 | 8 |
| 2024 | 1 | 10 | 11 |
| 2025 | 0 | 11 | 11 |
| 2026 | 0 | 2 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Reactive Oxygen Species" by people in Profiles.
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Suthar KP, Hounsell C, Fan Y, Bergmann A. Calcium signaling regulates apoptosis-induced proliferation in Drosophila. PLoS Biol. 2026 Jan; 24(1):e3003607.
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Chaugule S, Yang YS, Sato T, Mayer E, Shim JH. USP8-mediated mitochondrial regulation in osteoclasts is essential for skeletal development. Cell Mol Life Sci. 2026 Jan 15; 83(1):72.
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Zhan X, Xiao H, Wang Q, Luo J, Ma L, Zhang X, Tang J, Meng X. Natural killer cell nano-engagers drive ferroptosis-immunomodulation synergy via inhibition of the Interleukin-6-JAK2-STAT3 Axis. J Control Release. 2026 Feb 10; 390:114581.
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Minchenberg SB, Ribera MO, Hionides Gutierrez A, Datta A, Brezani V, Santos B, Hong SM, Kulkarni S, Nagesh PT, Szabo G. Unraveling the gastrointestinal tract's response to alcohol binges: Neutrophil recruitment, neutrophil extracellular traps, and intestinal injury. Alcohol Clin Exp Res (Hoboken). 2025 Dec; 49(12):2707-2720.
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Yang RZ, Wang Y, Wu Z, Luo Y, Wang DD, Zou Y, Liang Y, Li JK, Zhang S, Huang CP, Zeng WR, Chang SY, Li SM, Meng XY, Sun HF, Liu PP, Lei J, Xiang Y, Gu Y, Yan B, Cai SQ, Zhang J, Kang JS. Ambient light alleviates retinal neurodegeneration in mice by powering mitochondria via the engineered optoenergetic rhodopsin. Signal Transduct Target Ther. 2025 Oct 30; 10(1):355.
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Zhan X, Xiao H, Zhang X, Li S, Zhang W, Ma L, Tang J, Meng X. A metallic metabolic nano-regulator reprograms the PKM2/HIF-1a/DLAT axis to amplify tumor-specific cuproptosis. Biomaterials. 2026 Feb; 325:123626.
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Dehdashtian E, Caricchio R. From innate immunity to autoimmunity: Neutrophils in systemic lupus erythematosus pathogenesis. Lupus. 2025 Sep; 34(10):989-1002.
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Yigit K, Chien P. Lon-dependent proteolysis in oxidative stress responses. J Bacteriol. 2025 Jul 24; 207(7):e0000525.
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Kim M, Woo J, Kim J, Choi M, Shin HJ, Kim Y, Kim J, Shin DW. Iris germanica L. Rhizome-Derived Exosomes Ameliorated Dihydrotestosterone-Damaged Human Follicle Dermal Papilla Cells Through the Activation of Wnt/?-Catenin Pathway. Int J Mol Sci. 2025 Apr 25; 26(9).
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Go MY, Kim J, Jeon CY, Kim M, Shin DW. Pinitol Improves Lipopolysaccharide-Induced Cellular Damage in Human Dermal Microvascular Endothelial Cells. Molecules. 2025 Mar 28; 30(7).