Reactive Oxygen Species

"Reactive Oxygen Species" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of SIGNAL TRANSDUCTION and GENE EXPRESSION, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.

Descriptor ID	D017382
MeSH Number(s)	D01.339.431 D01.650.775
Concept/Terms	Reactive Oxygen Species Reactive Oxygen Species Oxygen Species, Reactive Active Oxygen Oxygen, Active Oxygen Radicals Pro-Oxidants Pro Oxidants

Below are MeSH descriptors whose meaning is more general than "Reactive Oxygen Species".

Chemicals and Drugs [D]
Inorganic Chemicals [D01]
Free Radicals [D01.339]
Reactive Oxygen Species [D01.339.431]
Oxygen Compounds [D01.650]
Reactive Oxygen Species [D01.650.775]

Below are MeSH descriptors whose meaning is related to "Reactive Oxygen Species".

Below are MeSH descriptors whose meaning is more specific than "Reactive Oxygen Species".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Reactive Oxygen Species" by people in this website by year, and whether "Reactive Oxygen Species" was a major or minor topic of these publications.

Bar chart showing 201 publications over 29 distinct years, with a maximum of 19 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1998	1	0	1
2000	0	2	2
2001	0	2	2
2002	3	1	4
2003	3	5	8
2004	2	4	6
2005	1	2	3
2006	0	2	2
2007	1	3	4
2008	1	3	4
2009	1	1	2
2010	1	10	11
2011	0	4	4
2012	1	1	2
2013	1	9	10
2014	0	19	19
2015	3	6	9
2016	5	10	15
2017	3	12	15
2018	1	11	12
2019	1	10	11
2020	1	4	5
2021	2	5	7
2022	0	8	8
2023	0	8	8
2024	1	10	11
2025	0	11	11
2026	0	4	4

Below are the most recent publications written about "Reactive Oxygen Species" by people in Profiles.

Antonelli LR, Gazzinelli RT. The mitochondrial metabolic shift in inflammatory monocytes during Plasmodium vivax malaria. Curr Opin Immunol. 2026 Jun; 100:102769.

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Valenzuela-Villatoro M, de la Cruz-Ruiz P, Guerrero-G?mez D, G?mez-Orte E, Schiavi A, Maglioni S, Montero M, Fonteriz RI, Casas-Mart?nez JC, Briand NE, Xu J, Rodriguez-Palero MJ, Artal-Sanz M, Olek K, Polaczyk J, Turek M, Pokrzywa W, Xu S, Irazoqui JE, McDonagh B, ?lvarez J, Olmedo M, Ventura N, Cabello J, Miranda-Vizuete A. Mitochondrial redox homeostasis links organellar stress surveillance to germline and somatic integrity in Caenorhabditis elegans. Redox Biol. 2026 Jun; 93:104115.

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Suthar KP, Hounsell C, Fan Y, Bergmann A. Calcium signaling regulates apoptosis-induced proliferation in Drosophila. PLoS Biol. 2026 Jan; 24(1):e3003607.

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Chaugule S, Yang YS, Sato T, Mayer E, Shim JH. USP8-mediated mitochondrial regulation in osteoclasts is essential for skeletal development. Cell Mol Life Sci. 2026 Jan 15; 83(1):72.

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Zhan X, Xiao H, Wang Q, Luo J, Ma L, Zhang X, Tang J, Meng X. Natural killer cell nano-engagers drive ferroptosis-immunomodulation synergy via inhibition of the Interleukin-6-JAK2-STAT3 Axis. J Control Release. 2026 Feb 10; 390:114581.

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Minchenberg SB, Ribera MO, Hionides Gutierrez A, Datta A, Brezani V, Santos B, Hong SM, Kulkarni S, Nagesh PT, Szabo G. Unraveling the gastrointestinal tract's response to alcohol binges: Neutrophil recruitment, neutrophil extracellular traps, and intestinal injury. Alcohol Clin Exp Res (Hoboken). 2025 Dec; 49(12):2707-2720.

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Yang RZ, Wang Y, Wu Z, Luo Y, Wang DD, Zou Y, Liang Y, Li JK, Zhang S, Huang CP, Zeng WR, Chang SY, Li SM, Meng XY, Sun HF, Liu PP, Lei J, Xiang Y, Gu Y, Yan B, Cai SQ, Zhang J, Kang JS. Ambient light alleviates retinal neurodegeneration in mice by powering mitochondria via the engineered optoenergetic rhodopsin. Signal Transduct Target Ther. 2025 Oct 30; 10(1):355.

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Zhan X, Xiao H, Zhang X, Li S, Zhang W, Ma L, Tang J, Meng X. A metallic metabolic nano-regulator reprograms the PKM2/HIF-1a/DLAT axis to amplify tumor-specific cuproptosis. Biomaterials. 2026 Feb; 325:123626.

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Dehdashtian E, Caricchio R. From innate immunity to autoimmunity: Neutrophils in systemic lupus erythematosus pathogenesis. Lupus. 2025 Sep; 34(10):989-1002.

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Yigit K, Chien P. Lon-dependent proteolysis in oxidative stress responses. J Bacteriol. 2025 Jul 24; 207(7):e0000525.

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