A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.

Descriptor ID	D009569
MeSH Number(s)	D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
Concept/Terms	Nitric Oxide Nitric Oxide Oxide, Nitric Nitrogen Monoxide Monoxide, Nitrogen Nitric Oxide, Endothelium-Derived Endothelium-Derived Nitric Oxide Nitric Oxide, Endothelium Derived Endogenous Nitrate Vasodilator Nitrate Vasodilator, Endogenous Vasodilator, Endogenous Nitrate Mononitrogen Monoxide Monoxide, Mononitrogen

Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".

Below are MeSH descriptors whose meaning is related to "Nitric Oxide".

Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".