"Receptor, EphA1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The founding member of the EPH FAMILY RECEPTORS. It was first cloned from an erythropoietin-producing human hepatocellular carcinoma cell line and is highly conserved among many mammalian species. Overproduction of the EphA1 receptor is associated with tumors and tumor cells of epithelial origin. It is also expressed at high levels in LIVER; LUNG; and KIDNEY; which is in contrast to many other members of the Eph receptor that are found primarily in tissues of the nervous system.
- Receptor, EphA1
- EPHA1 Receptor Tyrosine Kinase
- Eph Receptor
- EPHA1 Protein
- EphA1 Receptor
Below are MeSH descriptors whose meaning is more general than "Receptor, EphA1".
Below are MeSH descriptors whose meaning is more specific than "Receptor, EphA1".
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Below are the most recent publications written about "Receptor, EphA1" by people in Profiles.
Sahin M, Greer PL, Lin MZ, Poucher H, Eberhart J, Schmidt S, Wright TM, Shamah SM, O'connell S, Cowan CW, Hu L, Goldberg JL, Debant A, Corfas G, Krull CE, Greenberg ME. Eph-dependent tyrosine phosphorylation of ephexin1 modulates growth cone collapse. Neuron. 2005 Apr 21; 46(2):191-204.
Vergara-Silva A, Schaefer KL, Berg LJ. Compartmentalized Eph receptor and ephrin expression in the thymus. Mech Dev. 2002 Dec; 119 Suppl 1:S225-9.
Hinchcliffe EH, Sluder G. Centrosome duplication: three kinases come up a winner! Curr Biol. 2001 Sep 04; 11(17):R698-701.