"Receptors, Prolactin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Labile proteins on or in prolactin-sensitive cells that bind prolactin initiating the cells' physiological response to that hormone. Mammary casein synthesis is one of the responses. The receptors are also found in placenta, liver, testes, kidneys, ovaries, and other organs and bind and respond to certain other hormones and their analogs and antagonists. This receptor is related to the growth hormone receptor.
| Descriptor ID |
D011981
|
| MeSH Number(s) |
D12.776.543.750.720.600.710 D12.776.543.750.750.555.710 D12.776.543.750.750.660.350.725
|
| Concept/Terms |
Receptors, Prolactin- Receptors, Prolactin
- Prolactin Receptors
- Receptors, PRL
- PRL Receptors
- Prolactin Receptor
- Receptor, Prolactin
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Prolactin".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Prolactin [D12.776.543.750.720.600.710]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Prolactin [D12.776.543.750.750.555.710]
- Receptors, Pituitary Hormone [D12.776.543.750.750.660]
- Receptors, Gonadotropin [D12.776.543.750.750.660.350]
- Receptors, Prolactin [D12.776.543.750.750.660.350.725]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Prolactin".
This graph shows the total number of publications written about "Receptors, Prolactin" by people in this website by year, and whether "Receptors, Prolactin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Receptors, Prolactin" by people in Profiles.
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Hartwell HJ, Petrosky KY, Fox JG, Horseman ND, Rogers AB. Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice. Proc Natl Acad Sci U S A. 2014 Aug 05; 111(31):11455-60.
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Breves JP, Serizier SB, Goffin V, McCormick SD, Karlstrom RO. Prolactin regulates transcription of the ion uptake Na+/Cl- cotransporter (ncc) gene in zebrafish gill. Mol Cell Endocrinol. 2013 Apr 30; 369(1-2):98-106.
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Demirci C, Ernst S, Alvarez-Perez JC, Rosa T, Valle S, Shridhar V, Casinelli GP, Alonso LC, Vasavada RC, Garc?a-Ocana A. Loss of HGF/c-Met signaling in pancreatic ?-cells leads to incomplete maternal ?-cell adaptation and gestational diabetes mellitus. Diabetes. 2012 May; 61(5):1143-52.
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Kokay IC, Petersen SL, Grattan DR. Identification of prolactin-sensitive GABA and kisspeptin neurons in regions of the rat hypothalamus involved in the control of fertility. Endocrinology. 2011 Feb; 152(2):526-35.
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Mellai M, Giordano M, D'Alfonso S, Marchini M, Scorza R, Danieli M.G., Leone M, Ferro I, Liguori M, Trojano M, Ballerini C, Massacesi L, Cannoni S, Bomprezzi R, Momigliano-Richiardi P. Prolactin and prolactin receptor gene polymorphisms in multiple sclerosis and systemic lupus erythematosus. Hum Immunol. 2003 02; 64(2):274-84.
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Brisken C, Socolovsky M, Lodish HF, Weinberg R. The signaling domain of the erythropoietin receptor rescues prolactin receptor-mutant mammary epithelium. Proc Natl Acad Sci U S A. 2002 Oct 29; 99(22):14241-5.
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Leav I, Merk FB, Lee KF, Loda M, Mandoki M, McNeal JE, Ho SM. Prolactin receptor expression in the developing human prostate and in hyperplastic, dysplastic, and neoplastic lesions. Am J Pathol. 1999 Mar; 154(3):863-70.
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Socolovsky M, Fallon AE, Lodish HF. The prolactin receptor rescues EpoR-/- erythroid progenitors and replaces EpoR in a synergistic interaction with c-kit. Blood. 1998 Sep 01; 92(5):1491-6.
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Socolovsky M, Dusanter-Fourt I, Lodish HF. The prolactin receptor and severely truncated erythropoietin receptors support differentiation of erythroid progenitors. J Biol Chem. 1997 May 30; 272(22):14009-12.
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Reiter E, Bonnet P, Sente B, Dombrowicz D, de Leval J, Closset J, Hennen G. Growth hormone and prolactin stimulate androgen receptor, insulin-like growth factor-I (IGF-I) and IGF-I receptor levels in the prostate of immature rats. Mol Cell Endocrinol. 1992 Oct; 88(1-3):77-87.