GA-Binding Protein Transcription Factor
"GA-Binding Protein Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterotetrameric transcription factor composed of two distinct proteins. Its name refers to the fact it binds to DNA sequences rich in GUANINE and ADENINE. GA-binding protein integrates a variety of SIGNAL TRANSDUCTION PATHWAYS and regulates expression of GENES involved in CELL CYCLE control, PROTEIN BIOSYNTHESIS, and cellular METABOLISM.
| Descriptor ID |
D051268
|
| MeSH Number(s) |
D12.776.260.615.249 D12.776.930.618.249
|
| Concept/Terms |
GA-Binding Protein Transcription Factor- GA-Binding Protein Transcription Factor
- GA Binding Protein Transcription Factor
- Nuclear Respiratory Factor-2
- Respiratory Factor-2, Nuclear
- Nuclear Respiratory Factor 2
- GA-Binding Protein
- GA Binding Protein
- GABP Transcription Factor
- Transcription Factor, GABP
|
Below are MeSH descriptors whose meaning is more general than "GA-Binding Protein Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "GA-Binding Protein Transcription Factor".
This graph shows the total number of publications written about "GA-Binding Protein Transcription Factor" by people in this website by year, and whether "GA-Binding Protein Transcription Factor" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "GA-Binding Protein Transcription Factor" by people in Profiles.
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Malu K, Garhwal R, Pelletier MG, Gotur D, Halene S, Zwerger M, Yang ZF, Rosmarin AG, Gaines P. Cooperative Activity of GABP with PU.1 or C/EBPe Regulates Lamin B Receptor Gene Expression, Implicating Their Roles in Granulocyte Nuclear Maturation. J Immunol. 2016 08 01; 197(3):910-22.
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Yang ZF, Drumea K, Mott S, Wang J, Rosmarin AG. GABP transcription factor (nuclear respiratory factor 2) is required for mitochondrial biogenesis. Mol Cell Biol. 2014 Sep; 34(17):3194-201.
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Yang ZF, Zhang H, Ma L, Peng C, Chen Y, Wang J, Green MR, Li S, Rosmarin AG. GABP transcription factor is required for development of chronic myelogenous leukemia via its control of PRKD2. Proc Natl Acad Sci U S A. 2013 Feb 05; 110(6):2312-7.
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Yang ZF, Drumea K, Cormier J, Wang J, Zhu X, Rosmarin AG. GABP transcription factor is required for myeloid differentiation, in part, through its control of Gfi-1 expression. Blood. 2011 Aug 25; 118(8):2243-53.
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Yang ZF, Mott S, Rosmarin AG. The Ets transcription factor GABP is required for cell-cycle progression. Nat Cell Biol. 2007 Mar; 9(3):339-46.
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Resendes KK, Rosmarin AG. GA-binding protein and p300 are essential components of a retinoic acid-induced enhanceosome in myeloid cells. Mol Cell Biol. 2006 Apr; 26(8):3060-70.
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Lin JM, Weng Z. Systematic detection of statistically overrepresented DNA motif association rules. Genome Inform. 2006; 17(1):124-33.
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Rosmarin AG, Resendes KK, Yang Z, McMillan JN, Fleming SL. GA-binding protein transcription factor: a review of GABP as an integrator of intracellular signaling and protein-protein interactions. Blood Cells Mol Dis. 2004 Jan-Feb; 32(1):143-54.
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Bush TS, St Coeur M, Resendes KK, Rosmarin AG. GA-binding protein (GABP) and Sp1 are required, along with retinoid receptors, to mediate retinoic acid responsiveness of CD18 (beta 2 leukocyte integrin): a novel mechanism of transcriptional regulation in myeloid cells. Blood. 2003 Jan 01; 101(1):311-7.
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Gyrd-Hansen M, Krag TO, Rosmarin AG, Khurana TS. Sp1 and the ets-related transcription factor complex GABP alpha/beta functionally cooperate to activate the utrophin promoter. J Neurol Sci. 2002 May 15; 197(1-2):27-35.