rhoA GTP-Binding Protein

"rhoA GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A RHO GTP-BINDING PROTEIN involved in regulating signal transduction pathways that control assembly of focal adhesions and actin stress fibers. This enzyme was formerly listed as EC 3.6.1.47.

Descriptor ID	D020742
MeSH Number(s)	D08.811.277.040.330.300.400.700.200 D12.644.360.525.700.200 D12.776.157.325.515.700.200 D12.776.476.525.700.200
Concept/Terms	rhoA GTP-Binding Protein rhoA GTP-Binding Protein GTP-Binding Protein, rhoA rhoA GTP Binding Protein rhoA P21 Protein rho12 Protein ARHA GTP-Binding Protein ARHA GTP Binding Protein GTP-Binding Protein, ARHA rhoA Protein Ras Homolog Family Member A rho12 GTP-Binding Protein GTP-Binding Protein, rho12 rho12 GTP Binding Protein V14rho V14rho V14rhoA

Below are MeSH descriptors whose meaning is more general than "rhoA GTP-Binding Protein".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Acid Anhydride Hydrolases [D08.811.277.040]
GTP Phosphohydrolases [D08.811.277.040.330]
GTP-Binding Proteins [D08.811.277.040.330.300]
Monomeric GTP-Binding Proteins [D08.811.277.040.330.300.400]
rho GTP-Binding Proteins [D08.811.277.040.330.300.400.700]
rhoA GTP-Binding Protein [D08.811.277.040.330.300.400.700.200]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Monomeric GTP-Binding Proteins [D12.644.360.525]
rho GTP-Binding Proteins [D12.644.360.525.700]
rhoA GTP-Binding Protein [D12.644.360.525.700.200]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
GTP-Binding Proteins [D12.776.157.325]
Monomeric GTP-Binding Proteins [D12.776.157.325.515]
rho GTP-Binding Proteins [D12.776.157.325.515.700]
rhoA GTP-Binding Protein [D12.776.157.325.515.700.200]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Monomeric GTP-Binding Proteins [D12.776.476.525]
rho GTP-Binding Proteins [D12.776.476.525.700]
rhoA GTP-Binding Protein [D12.776.476.525.700.200]

Below are MeSH descriptors whose meaning is related to "rhoA GTP-Binding Protein".

Below are MeSH descriptors whose meaning is more specific than "rhoA GTP-Binding Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "rhoA GTP-Binding Protein" by people in this website by year, and whether "rhoA GTP-Binding Protein" was a major or minor topic of these publications.

Bar chart showing 24 publications over 18 distinct years, with a maximum of 3 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2000	1	0	1
2001	1	1	2
2002	1	1	2
2003	0	1	1
2004	1	0	1
2005	1	1	2
2006	1	0	1
2007	0	1	1
2008	1	2	3
2009	1	0	1
2010	1	0	1
2011	0	1	1
2013	1	0	1
2014	0	1	1
2015	1	0	1
2016	2	0	2
2017	0	1	1

Below are the most recent publications written about "rhoA GTP-Binding Protein" by people in Profiles.

Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, L?pez-Garc?a IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM. Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. 2017 11 09; 551(7679):227-231.

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Schierwagen R, Mayb?chen L, Hittatiya K, Klein S, Uschner FE, Braga TT, Franklin BS, Nickenig G, Strassburg CP, Plat J, Sauerbruch T, Latz E, L?tjohann D, Zimmer S, Trebicka J. Statins improve NASH via inhibition of RhoA and Ras. Am J Physiol Gastrointest Liver Physiol. 2016 10 01; 311(4):G724-G733.

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Saslowsky DE, Thiagarajah JR, McCormick BA, Lee JC, Lencer WI. Microbial sphingomyelinase induces RhoA-mediated reorganization of the apical brush border membrane and is protective against invasion. Mol Biol Cell. 2016 Apr 01; 27(7):1120-30.

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Son K, Smith TC, Luna EJ. Supervillin binds the Rac/Rho-GEF Trio and increases Trio-mediated Rac1 activation. Cytoskeleton (Hoboken). 2015 Jan; 72(1):47-64.

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Bhattacharya M, Sundaram A, Kudo M, Farmer J, Ganesan P, Khalifeh-Soltani A, Arjomandi M, Atabai K, Huang X, Sheppard D. IQGAP1-dependent scaffold suppresses RhoA and inhibits airway smooth muscle contraction. J Clin Invest. 2014 Nov; 124(11):4895-8.

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Fagan-Solis KD, Schneider SS, Pentecost BT, Bentley BA, Otis CN, Gierthy JF, Arcaro KF. The RhoA pathway mediates MMP-2 and MMP-9-independent invasive behavior in a triple-negative breast cancer cell line. J Cell Biochem. 2013 Jun; 114(6):1385-94.

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Luo R, Jeong SJ, Jin Z, Strokes N, Li S, Piao X. G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and lamination. Proc Natl Acad Sci U S A. 2011 Aug 02; 108(31):12925-30.

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Margolis SS, Salogiannis J, Lipton DM, Mandel-Brehm C, Wills ZP, Mardinly AR, Hu L, Greer PL, Bikoff JB, Ho HY, Soskis MJ, Sahin M, Greenberg ME. EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation. Cell. 2010 Oct 29; 143(3):442-55.

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Khatiwala CB, Kim PD, Peyton SR, Putnam AJ. ECM compliance regulates osteogenesis by influencing MAPK signaling downstream of RhoA and ROCK. J Bone Miner Res. 2009 May; 24(5):886-98.

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Murthy K, Wadsworth P. Dual role for microtubules in regulating cortical contractility during cytokinesis. J Cell Sci. 2008 Jul 15; 121(Pt 14):2350-9.

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