Matrix Metalloproteinase 2

"Matrix Metalloproteinase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A secreted endopeptidase homologous with INTERSTITIAL COLLAGENASE, but which possesses an additional fibronectin-like domain.

Descriptor ID	D020778
MeSH Number(s)	D08.811.277.656.300.480.205.352 D08.811.277.656.300.480.252.420 D08.811.277.656.300.480.525.700.150 D08.811.277.656.675.374.205.352 D08.811.277.656.675.374.252.420 D08.811.277.656.675.374.525.700.150 D12.644.276.848.150 D12.776.467.836.150
Concept/Terms	Matrix Metalloproteinase 2 Matrix Metalloproteinase 2 Metalloproteinase 2, Matrix 72-kDa Gelatinase 72 kDa Gelatinase Gelatinase, 72-kDa 72-kDa Type IV Collagenase 72 kDa Type IV Collagenase MMP-2 Metalloproteinase MMP 2 Metalloproteinase Metalloproteinase, MMP-2 Gelatinase A MMP2 Metalloproteinase Metalloproteinase, MMP2 Matrix Metalloproteinase-2

Below are MeSH descriptors whose meaning is more general than "Matrix Metalloproteinase 2".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Peptide Hydrolases [D08.811.277.656]
Endopeptidases [D08.811.277.656.300]
Metalloendopeptidases [D08.811.277.656.300.480]
Collagenases [D08.811.277.656.300.480.205]
Matrix Metalloproteinase 2 [D08.811.277.656.300.480.205.352]
Gelatinases [D08.811.277.656.300.480.252]
Matrix Metalloproteinase 2 [D08.811.277.656.300.480.252.420]
Matrix Metalloproteinases [D08.811.277.656.300.480.525]
Matrix Metalloproteinases, Secreted [D08.811.277.656.300.480.525.700]
Matrix Metalloproteinase 2 [D08.811.277.656.300.480.525.700.150]
Metalloproteases [D08.811.277.656.675]
Metalloendopeptidases [D08.811.277.656.675.374]
Collagenases [D08.811.277.656.675.374.205]
Matrix Metalloproteinase 2 [D08.811.277.656.675.374.205.352]
Gelatinases [D08.811.277.656.675.374.252]
Matrix Metalloproteinase 2 [D08.811.277.656.675.374.252.420]
Matrix Metalloproteinases [D08.811.277.656.675.374.525]
Matrix Metalloproteinases, Secreted [D08.811.277.656.675.374.525.700]
Matrix Metalloproteinase 2 [D08.811.277.656.675.374.525.700.150]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Matrix Metalloproteinases, Secreted [D12.644.276.848]
Matrix Metalloproteinase 2 [D12.644.276.848.150]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Matrix Metalloproteinases, Secreted [D12.776.467.836]
Matrix Metalloproteinase 2 [D12.776.467.836.150]

Below are MeSH descriptors whose meaning is more specific than "Matrix Metalloproteinase 2".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Matrix Metalloproteinase 2" by people in this website by year, and whether "Matrix Metalloproteinase 2" was a major or minor topic of these publications.

Bar chart showing 1 publications over 1 distinct years, with a maximum of 1 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2016	1	0	1

Below are the most recent publications written about "Matrix Metalloproteinase 2" by people in Profiles.

Biswas MHU, Almeida S, Lopez-Gonzalez R, Mao W, Zhang Z, Karydas A, Geschwind MD, Biernat J, Mandelkow EM, Futai K, Miller BL, Gao FB. MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations. Stem Cell Reports. 2016 09 13; 7(3):316-324.

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Dutta A, Li J, Lu H, Akech J, Pratap J, Wang T, Zerlanko BJ, FitzGerald TJ, Jiang Z, Birbe R, Wixted J, Violette SM, Stein JL, Stein GS, Lian JB, Languino LR. Integrin av?6 promotes an osteolytic program in cancer cells by upregulating MMP2. Cancer Res. 2014 Mar 01; 74(5):1598-608.

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Tanaka K, Essick EE, Doros G, Tanriverdi K, Connors LH, Seldin DC, Sam F. Circulating matrix metalloproteinases and tissue inhibitors of metalloproteinases in cardiac amyloidosis. J Am Heart Assoc. 2013 Mar 12; 2(2):e005868.

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Kolega J, Gao L, Mandelbaum M, Mocco J, Siddiqui AH, Natarajan SK, Meng H. Cellular and molecular responses of the basilar terminus to hemodynamics during intracranial aneurysm initiation in a rabbit model. J Vasc Res. 2011; 48(5):429-42.

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Biswas MH, Du C, Zhang C, Straubhaar J, Languino LR, Balaji KC. Protein kinase D1 inhibits cell proliferation through matrix metalloproteinase-2 and matrix metalloproteinase-9 secretion in prostate cancer. Cancer Res. 2010 Mar 01; 70(5):2095-104.

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Tao P, Fisher JF, Shi Q, Vreven T, Mobashery S, Schlegel HB. Matrix metalloproteinase 2 inhibition: combined quantum mechanics and molecular mechanics studies of the inhibition mechanism of (4-phenoxyphenylsulfonyl)methylthiirane and its oxirane analogue. Biochemistry. 2009 Oct 20; 48(41):9839-47.

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Maclauchlan S, Skokos EA, Agah A, Zeng J, Tian W, Davidson JM, Bornstein P, Kyriakides TR. Enhanced angiogenesis and reduced contraction in thrombospondin-2-null wounds is associated with increased levels of matrix metalloproteinases-2 and -9, and soluble VEGF. J Histochem Cytochem. 2009 Apr; 57(4):301-13.

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Manfredi MA, Zurakowski D, Rufo PA, Walker TR, Fox VL, Moses MA. Increased incidence of urinary matrix metalloproteinases as predictors of disease in pediatric patients with inflammatory bowel disease. Inflamm Bowel Dis. 2008 Aug; 14(8):1091-6.

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Mutlu A, Allen DJ, Freedman J, Leytin V. The level of matrix metalloproteinase-2 in donor plasma strongly correlates with post-transfusion recovery of stored platelet concentrates. Vox Sang. 2008 Feb; 94(2):143-5.

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