"Microbial Collagenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.
Descriptor ID |
D003012
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MeSH Number(s) |
D08.811.277.656.300.480.205.500 D08.811.277.656.675.374.205.500
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Concept/Terms |
Microbial Collagenase- Microbial Collagenase
- Clostridium histolyticum Collagenase
- Collagenase, Clostridium histolyticum
- Nucleolysin
- Collagenase, Microbial
- Collalysine
- Clostridiopeptidase A
- Collagenase Clostridium histolyticum
- Clostridium histolyticum, Collagenase
- histolyticum, Collagenase Clostridium
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Below are MeSH descriptors whose meaning is more general than "Microbial Collagenase".
Below are MeSH descriptors whose meaning is more specific than "Microbial Collagenase".
This graph shows the total number of publications written about "Microbial Collagenase" by people in this website by year, and whether "Microbial Collagenase" was a major or minor topic of these publications.
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Below are the most recent publications written about "Microbial Collagenase" by people in Profiles.
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Jung JU, Desrosiers RC. Identification and characterization of the herpesvirus saimiri oncoprotein STP-C488. J Virol. 1991 Dec; 65(12):6953-60.
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Gravallese EM, Darling JM, Ladd AL, Katz JN, Glimcher LH. In situ hybridization studies of stromelysin and collagenase messenger RNA expression in rheumatoid synovium. Arthritis Rheum. 1991 Sep; 34(9):1076-84.
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Ginns E, Guarnieri M. Trypsin bound to sephadex beads. A tool for neuronal cell dissociation. Exp Cell Res. 1976 Jan; 97:42-6.
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Guarnieri M, Cohen SR, Ginns E. Cells isolated from trypsin-treated brain contain trypsin. J Neurochem. 1976 Jan; 26(1):41-4.