"Caspase 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 3 and CASPASE 10. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
Descriptor ID |
D053179
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MeSH Number(s) |
D08.811.277.656.262.500.126.350.700 D08.811.277.656.300.200.126.350.700 D12.644.360.075.405.350.700 D12.776.476.075.405.350.700
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Concept/Terms |
Caspase 7- Caspase 7
- Caspase-7
- Mch-3 Protease
- Mch 3 Protease
- Protease, Mch-3
- Apoptotic Protease Mch-3
- Apoptotic Protease Mch 3
- Mch-3, Apoptotic Protease
- Protease Mch-3, Apoptotic
- ICE-Like Apoptotic Protease 3
- ICE Like Apoptotic Protease 3
Procaspase 7- Procaspase 7
- Pro-caspase-7
- Procaspase-7
- Pro-caspase 7
- Pro caspase 7
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Below are MeSH descriptors whose meaning is more general than "Caspase 7".
Below are MeSH descriptors whose meaning is more specific than "Caspase 7".
This graph shows the total number of publications written about "Caspase 7" by people in this website by year, and whether "Caspase 7" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2009 | 2 | 1 | 3 |
2011 | 1 | 1 | 2 |
2012 | 0 | 2 | 2 |
2013 | 0 | 2 | 2 |
2014 | 0 | 2 | 2 |
2016 | 2 | 0 | 2 |
2017 | 1 | 1 | 2 |
2019 | 1 | 0 | 1 |
2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Caspase 7" by people in Profiles.
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Zhou JY, Fitzgerald KA. Hold your horses! Reining in your fastest pores with caspase-7. Immunity. 2022 08 09; 55(8):1340-1342.
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Pham B, Eron SJ, Hill ME, Li X, Fahie MA, Hardy JA, Chen M. A Nanopore Approach for Analysis of Caspase-7 Activity in Cell Lysates. Biophys J. 2019 09 03; 117(5):844-855.
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Venkatesh A, Cheng SY, Punzo C. Loss of the cone-enriched caspase-7 does not affect secondary cone death in retinitis pigmentosa. Mol Vis. 2017; 23:944-951.
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Dagbay KB, Bolik-Coulon N, Savinov SN, Hardy JA. Caspase-6 Undergoes a Distinct Helix-Strand Interconversion upon Substrate Binding. J Biol Chem. 2017 03 24; 292(12):4885-4897.
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Eron SJ, Raghupathi K, Hardy JA. Dual Site Phosphorylation of Caspase-7 by PAK2 Blocks Apoptotic Activity by Two Distinct Mechanisms. Structure. 2017 01 03; 25(1):27-39.
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Hill ME, MacPherson DJ, Wu P, Julien O, Wells JA, Hardy JA. Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition. ACS Chem Biol. 2016 06 17; 11(6):1603-12.
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Zhang W, Xiao H, Parkin KL. Apoptosis in MCF-7 breast cancer cells induced by S-alkenylmercaptocysteine (CySSR) species derived from Allium tissues in combination with sodium selenite. Food Chem Toxicol. 2014 Jun; 68:1-10.
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Sun YR, Zhang SH, Shao RG, He HW. [The synergistic effect of lidamycin and rituximab on human B cell lymphoma]. Yao Xue Xue Bao. 2014 Feb; 49(2):198-203.
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Godinat A, Park HM, Miller SC, Cheng K, Hanahan D, Sanman LE, Bogyo M, Yu A, Nikitin GF, Stahl A, Dubikovskaya EA. A biocompatible in vivo ligation reaction and its application for noninvasive bioluminescent imaging of protease activity in living mice. ACS Chem Biol. 2013 May 17; 8(5):987-99.
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Podolin PL, Foley JP, Carpenter DC, Bolognese BJ, Logan GA, Long E, Harrison OJ, Walsh PT. T cell depletion protects against alveolar destruction due to chronic cigarette smoke exposure in mice. Am J Physiol Lung Cell Mol Physiol. 2013 Mar 01; 304(5):L312-23.