Serotonin Plasma Membrane Transport Proteins

"Serotonin Plasma Membrane Transport Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of serotonergic neurons. They are different than SEROTONIN RECEPTORS, which signal cellular responses to SEROTONIN. They remove SEROTONIN from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. Regulates signal amplitude and duration at serotonergic synapses and is the site of action of the SEROTONIN UPTAKE INHIBITORS.

Descriptor ID	D050486
MeSH Number(s)	D12.776.157.530.450.625.311 D12.776.157.530.562.374.875 D12.776.157.530.937.624 D12.776.543.585.450.625.374 D12.776.543.585.562.374.875 D12.776.543.585.937.747
Concept/Terms	Serotonin Plasma Membrane Transport Proteins Serotonin Plasma Membrane Transport Proteins Serotonin Plasma Membrane Transporter Proteins Neurotransmitter Transporters, Serotonin-Specific Neurotransmitter Transporters, Serotonin Specific Serotonin-Specific Neurotransmitter Transporters 5-Hydroxytryptamine Plasma Membrane Transport Protein 5 Hydroxytryptamine Plasma Membrane Transport Protein Neurotransmitter Transport Proteins, Serotonin-Specific Neurotransmitter Transport Proteins, Serotonin Specific Serotonin Transporter SERT Proteins Solute Carrier Family 6, Member 4 Protein Solute Carrier Family 6, Member 4 Protein Sodium-Dependent Serotonin Transporter Serotonin Transporter, Sodium-Dependent Sodium Dependent Serotonin Transporter Transporter, Sodium-Dependent Serotonin 5HT Transporter SLC6A4 Protein Serotonectin Serotonectin Platelet Serotonin Transporter Serotonin Transporter, Platelet Serotonin Transporter, Platelets Platelets Serotonin Transporter

Below are MeSH descriptors whose meaning is more general than "Serotonin Plasma Membrane Transport Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Membrane Transport Proteins [D12.776.157.530]
Ion Pumps [D12.776.157.530.450]
Symporters [D12.776.157.530.450.625]
Serotonin Plasma Membrane Transport Proteins [D12.776.157.530.450.625.311]
Neurotransmitter Transport Proteins [D12.776.157.530.562]
Plasma Membrane Neurotransmitter Transport Proteins [D12.776.157.530.562.374]
Serotonin Plasma Membrane Transport Proteins [D12.776.157.530.562.374.875]
Solute Carrier Proteins [D12.776.157.530.937]
Serotonin Plasma Membrane Transport Proteins [D12.776.157.530.937.624]
Membrane Proteins [D12.776.543]
Membrane Transport Proteins [D12.776.543.585]
Ion Pumps [D12.776.543.585.450]
Symporters [D12.776.543.585.450.625]
Serotonin Plasma Membrane Transport Proteins [D12.776.543.585.450.625.374]
Neurotransmitter Transport Proteins [D12.776.543.585.562]
Plasma Membrane Neurotransmitter Transport Proteins [D12.776.543.585.562.374]
Serotonin Plasma Membrane Transport Proteins [D12.776.543.585.562.374.875]
Solute Carrier Proteins [D12.776.543.585.937]
Serotonin Plasma Membrane Transport Proteins [D12.776.543.585.937.747]

Below are MeSH descriptors whose meaning is related to "Serotonin Plasma Membrane Transport Proteins".

Below are MeSH descriptors whose meaning is more specific than "Serotonin Plasma Membrane Transport Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Serotonin Plasma Membrane Transport Proteins" by people in this website by year, and whether "Serotonin Plasma Membrane Transport Proteins" was a major or minor topic of these publications.

Bar chart showing 24 publications over 11 distinct years, with a maximum of 7 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	0	1	1
2004	0	3	3
2005	3	0	3
2008	2	1	3
2009	4	3	7
2010	1	1	2
2013	1	0	1
2016	0	1	1
2017	0	1	1
2019	0	1	1

Below are the most recent publications written about "Serotonin Plasma Membrane Transport Proteins" by people in Profiles.

Miozzo R, Eaton WW, Joseph Bienvenu O, Samuels J, Nestadt G. The serotonin transporter gene polymorphism (SLC6A4) and risk for psychiatric morbidity and comorbidity in the Baltimore ECA follow-up study. Compr Psychiatry. 2020 10; 102:152199.

View in: PubMed
Greden JF, Parikh SV, Rothschild AJ, Thase ME, Dunlop BW, DeBattista C, Conway CR, Forester BP, Mondimore FM, Shelton RC, Macaluso M, Li J, Brown K, Gilbert A, Burns L, Jablonski MR, Dechairo B. Impact of pharmacogenomics on clinical outcomes in major depressive disorder in the GUIDED trial: A large, patient- and rater-blinded, randomized, controlled study. J Psychiatr Res. 2019 04; 111:59-67.

View in: PubMed
Haynes RL, Frelinger AL, Giles EK, Goldstein RD, Tran H, Kozakewich HP, Haas EA, Gerrits AJ, Mena OJ, Trachtenberg FL, Paterson DS, Berry GT, Adeli K, Kinney HC, Michelson AD. High serum serotonin in sudden infant death syndrome. Proc Natl Acad Sci U S A. 2017 07 18; 114(29):7695-7700.

View in: PubMed
Sweeney CG, Tremblay BP, Stockner T, Sitte HH, Melikian HE. Dopamine Transporter Amino and Carboxyl Termini Synergistically Contribute to Substrate and Inhibitor Affinities. J Biol Chem. 2017 01 27; 292(4):1302-1309.

View in: PubMed
Piper BJ, Henderson CS, Meyer JS. Adolescent MDMA exposure diminishes the physiological and neurotoxic consequences of an MDMA binge in female rats. Dev Psychobiol. 2014 Jul; 56(5):924-34.

View in: PubMed
Piper BJ, Ali SF, Daniels LG, Meyer JS. Repeated intermittent methylenedioxymethamphetamine exposure protects against the behavioral and neurotoxic, but not hyperthermic, effects of an MDMA binge in adult rats. Synapse. 2010 Jun; 64(6):421-31.

View in: PubMed
Landaas ET, Johansson S, Jacobsen KK, Ribas?s M, Bosch R, S?nchez-Mora C, Jacob CP, Boreatti-H?mmer A, Kreiker S, Lesch KP, Kiemeney LA, Kooij JJ, Kan C, Buitelaar JK, Faraone SV, Halm?y A, Ramos-Quiroga JA, Cormand B, Reif A, Franke B, Mick E, Knappskog PM, Haavik J. An international multicenter association study of the serotonin transporter gene in persistent ADHD. Genes Brain Behav. 2010 Jul; 9(5):449-58.

View in: PubMed
Biezonski DK, Meyer JS. Effects of 3,4-methylenedioxymethamphetamine (MDMA) on serotonin transporter and vesicular monoamine transporter 2 protein and gene expression in rats: implications for MDMA neurotoxicity. J Neurochem. 2010 Feb; 112(4):951-62.

View in: PubMed
Monuteaux MC, Biederman J, Doyle AE, Mick E, Faraone SV. Genetic risk for conduct disorder symptom subtypes in an ADHD sample: specificity to aggressive symptoms. J Am Acad Child Adolesc Psychiatry. 2009 Jul; 48(7):757-764.

View in: PubMed
Aronin N. Expanded CAG repeats in the crosshairs. Nat Biotechnol. 2009 May; 27(5):451-2.

View in: PubMed

People

Explore

Similar Concepts

Top Journals