Sodium-Hydrogen Exchangers

"Sodium-Hydrogen Exchangers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of plasma membrane exchange glycoprotein antiporters that transport sodium ions and protons across lipid bilayers. They have critical functions in intracellular pH regulation, cell volume regulation, and cellular response to many different hormones and mitogens.

Descriptor ID	D017923
MeSH Number(s)	D12.776.157.530.450.162.775 D12.776.157.530.937.703 D12.776.543.550.190.775 D12.776.543.585.450.162.775 D12.776.543.585.937.828
Concept/Terms	Sodium-Hydrogen Exchangers Sodium-Hydrogen Exchangers Exchangers, Sodium-Hydrogen Sodium Hydrogen Exchangers Na(+)-H(+)-Antiporter Na(+)-H(+)-Exchangers Sodium-Proton Antiporters Antiporters, Sodium-Proton Sodium Proton Antiporters Solute Carrier 9 Proteins SLC9 Na(+)-H(+) Exchangers SLC9 Protein Family Protein Family, SLC9 SLC9-NHE Protein Family Protein Family, SLC9-NHE SLC9 NHE Protein Family SLC9 Proteins Solute Carrier 9 Protein Family Sodium-Hydrogen Antiporter Antiporter, Sodium-Hydrogen Sodium Hydrogen Antiporter Na(+)-H(+)-Exchanger Sodium-Hydrogen Exchanger Exchanger, Sodium-Hydrogen Sodium Hydrogen Exchanger Sodium-Proton Antiporter Antiporter, Sodium-Proton Sodium Proton Antiporter Sodium-Hydrogen Antiporters Antiporters, Sodium-Hydrogen Sodium Hydrogen Antiporters Na(+)-H(+)-Antiporters

Below are MeSH descriptors whose meaning is more general than "Sodium-Hydrogen Exchangers".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Membrane Transport Proteins [D12.776.157.530]
Ion Pumps [D12.776.157.530.450]
Antiporters [D12.776.157.530.450.162]
Sodium-Hydrogen Exchangers [D12.776.157.530.450.162.775]
Solute Carrier Proteins [D12.776.157.530.937]
Sodium-Hydrogen Exchangers [D12.776.157.530.937.703]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
Antiporters [D12.776.543.550.190]
Sodium-Hydrogen Exchangers [D12.776.543.550.190.775]
Membrane Transport Proteins [D12.776.543.585]
Ion Pumps [D12.776.543.585.450]
Antiporters [D12.776.543.585.450.162]
Sodium-Hydrogen Exchangers [D12.776.543.585.450.162.775]
Solute Carrier Proteins [D12.776.543.585.937]
Sodium-Hydrogen Exchangers [D12.776.543.585.937.828]

Below are MeSH descriptors whose meaning is related to "Sodium-Hydrogen Exchangers".

Below are MeSH descriptors whose meaning is more specific than "Sodium-Hydrogen Exchangers".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Sodium-Hydrogen Exchangers" by people in this website by year, and whether "Sodium-Hydrogen Exchangers" was a major or minor topic of these publications.

Bar chart showing 3 publications over 3 distinct years, with a maximum of 1 publications in 2002 and 2012 and 2026

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2012	1	0	1
2026	0	1	1

Below are the most recent publications written about "Sodium-Hydrogen Exchangers" by people in Profiles.

Molfetta DD, Ardone M, Fracasso F, Greco MR, Tamma G, Centrone M, Barile M, Tolomeo M, Nisco A, Reshkin SJ, Cardone RA. Extracellular pH and NHE1 Regulate Ductal Branching Morphogenesis in Organotypic Cultures of Human Pancreatic Duct Epithelial Cells. J Cell Physiol. 2026 Mar; 241(3):e70156.

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Dudakovic A, Camilleri ET, Lewallen EA, McGee-Lawrence ME, Riester SM, Kakar S, Montecino M, Stein GS, Ryoo HM, Dietz AB, Westendorf JJ, van Wijnen AJ. Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells. J Cell Physiol. 2015 Jan; 230(1):52-62.

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Ch?vez JC, Hern?ndez-Gonz?lez EO, Wertheimer E, Visconti PE, Darszon A, Trevi?o CL. Participation of the Cl-/HCO(3)- exchangers SLC26A3 and SLC26A6, the Cl- channel CFTR, and the regulatory factor SLC9A3R1 in mouse sperm capacitation. Biol Reprod. 2012 Jan; 86(1):1-14.

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Perdu B, Odgren PR, Van Wesenbeeck L, Jennes K, Mackay CC, Van Hul W. Refined genomic localization of the genetic lesion in the osteopetrosis (op) rat and exclusion of three positional and functional candidate genes, Clcn7, Atp6v0c, and Slc9a3r2. Calcif Tissue Int. 2009 May; 84(5):355-60.

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Gatto CL, Walker BJ, Lambert S. Asymmetric ERM activation at the Schwann cell process tip is required in axon-associated motility. J Cell Physiol. 2007 Jan; 210(1):122-32.

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Gatto CL, Walker BJ, Lambert S. Local ERM activation and dynamic growth cones at Schwann cell tips implicated in efficient formation of nodes of Ranvier. J Cell Biol. 2003 Aug 04; 162(3):489-98.

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Weinman EJ, Lakkis J, Akom M, Wali RK, Drachenberg CB, Coleman RA, Wade JB. Expression of NHERF-1, NHERF-2, PDGFR-alpha, and PDGFR-beta in normal human kidneys and in renal transplant rejection. Pathobiology. 2002-2003; 70(6):314-23.

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Pilitsis JG, Diaz FG, O'Regan MH, Phillis JW. Inhibition of Na(+)/H(+) exchange by SM-20220 attenuates free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury. Brain Res. 2001 Sep 21; 913(2):156-8.

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Ellstrom DR, Honeyman TW, Scheid CR. Role of blood pressure in regulating Na+/H+ exchange in vascular smooth muscle. Am J Hypertens. 1994 Apr; 7(4 Pt 1):340-5.

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Ellstrom DR, Foster CD, Honeyman TW, Scheid CR. Regulation of Na+/H+ exchange in mesenteric arteries from spontaneously hypertensive rats. Am J Hypertens. 1993 Jan; 6(1):21-7.

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