Acrosome Reaction

"Acrosome Reaction" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Changes that occur to liberate the enzymes of the ACROSOME of a sperm (SPERMATOZOA). Acrosome reaction allows the sperm to penetrate the ZONA PELLUCIDA and enter the OVUM during FERTILIZATION.

Descriptor ID	D020101
MeSH Number(s)	G08.686.784.277.800.100
Concept/Terms	Acrosome Reaction Acrosome Reaction Acrosome Reactions Reaction, Acrosome Reactions, Acrosome

Below are MeSH descriptors whose meaning is more general than "Acrosome Reaction".

Biological Sciences [G]
Reproductive and Urinary Physiological Phenomena [G08]
Reproductive Physiological Phenomena [G08.686]
Reproduction [G08.686.784]
Fertilization [G08.686.784.277]
Sperm-Ovum Interactions [G08.686.784.277.800]
Acrosome Reaction [G08.686.784.277.800.100]

Below are MeSH descriptors whose meaning is related to "Acrosome Reaction".

Below are MeSH descriptors whose meaning is more specific than "Acrosome Reaction".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Acrosome Reaction" by people in this website by year, and whether "Acrosome Reaction" was a major or minor topic of these publications.

Bar chart showing 34 publications over 20 distinct years, with a maximum of 3 publications in 2002 and 2008 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	0	1
2001	0	1	1
2002	2	1	3
2003	0	2	2
2004	1	0	1
2005	0	1	1
2006	1	1	2
2007	0	2	2
2008	3	0	3
2009	1	0	1
2010	1	0	1
2012	1	0	1
2013	0	3	3
2015	1	1	2
2016	1	1	2
2018	1	0	1
2019	1	1	2
2021	1	1	2
2024	1	1	2
2025	1	0	1

Below are the most recent publications written about "Acrosome Reaction" by people in Profiles.

S?nchez C?rdenas C, Hern?ndez-Cruz A, Visconti PE, Darszon A. Real-Time Acrosome Reaction and Intracellular Calcium Recordings in Mice Sperm. Methods Mol Biol. 2025; 2897:417-433.

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S?nchez-C?rdenas C, De la Vega-Beltr?n JL, Weber WD, Orta G, S?nchez-Guevara Y, Hern?ndez-Cruz A, Darszon A, Visconti PE. Intracellular Mg2+ concentrations are differentially regulated in the sperm head and mid-piece in acrosome reaction inducing conditions. FASEB J. 2024 Nov 15; 38(21):e70129.

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Arroyo-Salvo C, R?o S, Bogetti ME, Plaza J, Miragaya M, Yaneff A, Davio C, Fissore R, Gervasi MG, Gambini A, Perez-Martinez S. Effect of bicarbonate and polyvinyl alcohol on in vitro capacitation and fertilization ability of cryopreserved equine spermatozoa. Andrology. 2025 Feb; 13(2):382-395.

View in: PubMed
Balestrini PA, Sanchez-Cardenas C, Luque GM, Baro Graf C, Sierra JM, Hern?ndez-Cruz A, Visconti PE, Krapf D, Darszon A, Buffone MG. Membrane hyperpolarization abolishes calcium oscillations that prevent induced acrosomal exocytosis in human sperm. FASEB J. 2021 06; 35(6):e21478.

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S?nchez-C?rdenas C, Romarowski A, Orta G, De la Vega-Beltr?n JL, Mart?n-Hidalgo D, Hern?ndez-Cruz A, Visconti PE, Darszon A. Starvation induces an increase in intracellular calcium and potentiates the progesterone-induced mouse sperm acrosome reaction. FASEB J. 2021 04; 35(4):e21528.

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Wang Z, Shi Y, Ma S, Huang Q, Yap YT, Shi L, Zhang S, Zhou T, Li W, Hu B, Zhang L, Krawetz SA, Pazour GJ, Hess RA, Zhang Z. Abnormal fertility, acrosome formation, IFT20 expression and localization in conditional Gmap210 knockout mice. Am J Physiol Cell Physiol. 2020 01 01; 318(1):C174-C190.

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Garc?a-V?zquez FA, Soriano-?beda C, Laguna-Barraza R, Izquierdo-Rico MJ, Navarrete FA, Visconti PE, Guti?rrez-Ad?n A, Coy P. Tissue plasminogen activator (tPA) of paternal origin is necessary for the success of in vitro but not of in vivo fertilisation in the mouse. Reprod Fertil Dev. 2019 Mar; 31(3):433-442.

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Stival C, Ritagliati C, Xu X, Gervasi MG, Luque GM, Bar? Graf C, De la Vega-Beltr?n JL, Torres N, Darszon A, Krapf D, Buffone MG, Visconti PE, Krapf D. Disruption of protein kinase A localization induces acrosomal exocytosis in capacitated mouse sperm. J Biol Chem. 2018 06 15; 293(24):9435-9447.

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Puga Molina LC, Pinto NA, Torres Rodr?guez P, Romarowski A, Vicens Sanchez A, Visconti PE, Darszon A, Trevi?o CL, Buffone MG. Essential Role of CFTR in PKA-Dependent Phosphorylation, Alkalinization, and Hyperpolarization During Human Sperm Capacitation. J Cell Physiol. 2017 Jun; 232(6):1404-1414.

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Stival C, Puga Molina Ldel C, Paudel B, Buffone MG, Visconti PE, Krapf D. Sperm Capacitation and Acrosome Reaction in Mammalian Sperm. Adv Anat Embryol Cell Biol. 2016; 220:93-106.

View in: PubMed

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