Immunodominant Epitopes

"Immunodominant Epitopes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Subunits of the antigenic determinant that are most easily recognized by the immune system and thus most influence the specificity of the induced antibody.

Descriptor ID	D016056
MeSH Number(s)	D23.050.550.500
Concept/Terms	Immunodominant Epitopes Immunodominant Epitopes Immunodominant Determinants Determinants, Immunodominant Immunodominant Domains Domains, Immunodominant Immunodominant Sites Sites, Immunodominant Immunodominant Regions Regions, Immunodominant Antigenic Determinants, Immunodominant Determinants, Immunodominant Antigenic Immunodominant Antigenic Determinants Epitopes, Immunodominant Antigens, Immunodominant Antigens, Immunodominant Immunodominant Antigens

Below are MeSH descriptors whose meaning is more general than "Immunodominant Epitopes".

Chemicals and Drugs [D]
Biological Factors [D23]
Antigens [D23.050]
Epitopes [D23.050.550]
Immunodominant Epitopes [D23.050.550.500]

Below are MeSH descriptors whose meaning is related to "Immunodominant Epitopes".

Below are MeSH descriptors whose meaning is more specific than "Immunodominant Epitopes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Immunodominant Epitopes" by people in this website by year, and whether "Immunodominant Epitopes" was a major or minor topic of these publications.

Bar chart showing 39 publications over 20 distinct years, with a maximum of 5 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	2	0	2
1999	3	0	3
2000	1	0	1
2001	1	0	1
2002	1	0	1
2003	0	1	1
2005	0	2	2
2006	1	1	2
2007	0	3	3
2008	1	2	3
2009	1	1	2
2010	1	4	5
2013	0	1	1
2014	0	1	1
2015	1	1	2
2017	2	0	2
2018	0	1	1
2019	2	1	3
2020	1	1	2

Below are the most recent publications written about "Immunodominant Epitopes" by people in Profiles.

Shapiro MR, Yeh WI, Longfield JR, Gallagher J, Infante CM, Wellford S, Posgai AL, Atkinson MA, Campbell-Thompson M, Lieberman SM, Serreze DV, Geurts AM, Chen YG, Brusko TM. CD226 Deletion Reduces Type 1 Diabetes in the NOD Mouse by Impairing Thymocyte Development and Peripheral T Cell Activation. Front Immunol. 2020; 11:2180.

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Gil A, Kamga L, Chirravuri-Venkata R, Aslan N, Clark F, Ghersi D, Luzuriaga K, Selin LK. Epstein-Barr Virus Epitope-Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor a and ? Repertoires. mBio. 2020 03 17; 11(2).

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Kamga L, Gil A, Song I, Brody R, Ghersi D, Aslan N, Stern LJ, Selin LK, Luzuriaga K. CDR3a?drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection. PLoS Pathog. 2019 11; 15(11):e1008122.

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Mutsvunguma LZ, Rodriguez E, Escalante GM, Muniraju M, Williams JC, Warden C, Qin H, Wang J, Wu X, Barasa A, Mulama DH, Mwangi W, Ogembo JG. Identification of multiple potent neutralizing and non-neutralizing antibodies against Epstein-Barr virus gp350 protein with potential for clinical application and as reagents for mapping immunodominant epitopes. Virology. 2019 10; 536:1-15.

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Becerra-Artiles A, Cruz J, Leszyk JD, Sidney J, Sette A, Shaffer SA, Stern LJ. Naturally processed HLA-DR3-restricted HHV-6B peptides are recognized broadly with polyfunctional and cytotoxic CD4 T-cell responses. Eur J Immunol. 2019 08; 49(8):1167-1185.

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Nanaware PP, Jurewicz MM, Leszyk JD, Shaffer SA, Stern LJ. HLA-DO Modulates the Diversity of the MHC-II Self-peptidome. Mol Cell Proteomics. 2019 03; 18(3):490-503.

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Magnani DM, Silveira CGT, Rosen BC, Ricciardi MJ, Pedre?o-Lopez N, Gutman MJ, Bailey VK, Maxwell HS, Domingues A, Gonzalez-Nieto L, Avelino-Silva VI, Trindade M, Nogueira J, Oliveira CS, Maestri A, Felix AC, Levi JE, Nogueira ML, Martins MA, Martinez-Navio JM, Fuchs SP, Whitehead SS, Burton DR, Desrosiers RC, Kallas EG, Watkins DI. A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus. PLoS Negl Trop Dis. 2017 Jun; 11(6):e0005655.

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Song I, Gil A, Mishra R, Ghersi D, Selin LK, Stern LJ. Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope. Nat Struct Mol Biol. 2017 04; 24(4):395-406.

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Becerra-Artiles A, Dominguez-Amorocho O, Stern LJ, Calvo-Calle JM. A Simple Proteomics-Based Approach to Identification of Immunodominant Antigens from a Complex Pathogen: Application to the CD4 T Cell Response against Human Herpesvirus 6B. PLoS One. 2015; 10(11):e0142871.

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Nunes-Alves C, Booty MG, Carpenter SM, Rothchild AC, Martin CJ, Desjardins D, Steblenko K, Kl?verpris HN, Madansein R, Ramsuran D, Leslie A, Correia-Neves M, Behar SM. Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection. PLoS Pathog. 2015 May; 11(5):e1004849.

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