"Casein Kinase I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A casein kinase that was originally described as a monomeric enzyme with a molecular weight of 30-40 kDa. Several ISOENZYMES of casein kinase I have been found which are encoded by separate genes. Many of the casein kinase I isoenzymes have been shown to play distinctive roles in intracellular SIGNAL TRANSDUCTION.
| Descriptor ID |
D047389
|
| MeSH Number(s) |
D05.500.117.750 D08.811.913.696.620.682.700.140.300 D12.776.476.081.750 D12.776.476.150.299
|
| Concept/Terms |
Casein Kinase I- Casein Kinase I
- Kinase I, Casein
- Protein Kinase CKI
- Casein Kinase 1
- Kinase 1, Casein
- Protein Kinase CK1
|
Below are MeSH descriptors whose meaning is more general than "Casein Kinase I".
Below are MeSH descriptors whose meaning is more specific than "Casein Kinase I".
This graph shows the total number of publications written about "Casein Kinase I" by people in this website by year, and whether "Casein Kinase I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Casein Kinase I" by people in Profiles.
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Wager TT, Chandrasekaran RY, Bradley J, Rubitski D, Berke H, Mente S, Butler T, Doran A, Chang C, Fisher K, Knafels J, Liu S, Ohren J, Marconi M, DeMarco G, Sneed B, Walton K, Horton D, Rosado A, Mead A. Casein kinase 1d/e inhibitor PF-5006739 attenuates opioid drug-seeking behavior. ACS Chem Neurosci. 2014 Dec 17; 5(12):1253-65.
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Lee HM, Chen R, Kim H, Etchegaray JP, Weaver DR, Lee C. The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1. Proc Natl Acad Sci U S A. 2011 Sep 27; 108(39):16451-6.
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Bedri S, Cizek SM, Rastarhuyeva I, Stone JR. Regulation of protein kinase CK1alphaLS by dephosphorylation in response to hydrogen peroxide. Arch Biochem Biophys. 2007 Oct 15; 466(2):242-9.