Cryoelectron Microscopy

"Cryoelectron Microscopy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Electron microscopy involving rapid freezing of the samples. The imaging of frozen-hydrated molecules and organelles permits the best possible resolution closest to the living state, free of chemical fixatives or stains.

Descriptor ID	D020285
MeSH Number(s)	E01.370.350.515.402.150 E05.595.402.150
Concept/Terms	Cryoelectron Microscopy Cryoelectron Microscopy Cryoelectron Microscopies Microscopies, Cryoelectron Microscopy, Cryoelectron Electron Cryomicroscopy Cryomicroscopies, Electron Cryomicroscopy, Electron Electron Cryomicroscopies Cryo-electron Microscopy Cryo electron Microscopy Cryo-electron Microscopies Microscopies, Cryo-electron Microscopy, Cryo-electron

Below are MeSH descriptors whose meaning is more general than "Cryoelectron Microscopy".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Diagnosis [E01]
Diagnostic Techniques and Procedures [E01.370]
Diagnostic Imaging [E01.370.350]
Microscopy [E01.370.350.515]
Microscopy, Electron [E01.370.350.515.402]
Cryoelectron Microscopy [E01.370.350.515.402.150]
Investigative Techniques [E05]
Microscopy [E05.595]
Microscopy, Electron [E05.595.402]
Cryoelectron Microscopy [E05.595.402.150]

Below are MeSH descriptors whose meaning is related to "Cryoelectron Microscopy".

Below are MeSH descriptors whose meaning is more specific than "Cryoelectron Microscopy".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cryoelectron Microscopy" by people in this website by year, and whether "Cryoelectron Microscopy" was a major or minor topic of these publications.

Bar chart showing 155 publications over 26 distinct years, with a maximum of 15 publications in 2025

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
1999	0	1	1
2002	0	2	2
2003	2	1	3
2004	2	2	4
2005	0	1	1
2006	2	0	2
2007	2	1	3
2008	1	4	5
2009	1	3	4
2010	1	4	5
2011	3	3	6
2012	2	3	5
2013	1	2	3
2014	0	2	2
2015	7	2	9
2016	2	5	7
2017	3	6	9
2018	3	6	9
2019	1	9	10
2020	2	11	13
2021	3	7	10
2022	1	9	10
2023	1	7	8
2024	3	5	8
2025	5	10	15

Below are the most recent publications written about "Cryoelectron Microscopy" by people in Profiles.

Serrano A, Puerner C, Chevalier L, Plumb E, Elferich J, Diggs S, Sinn LR, Grigorieff N, Ralser M, Delarue M, Bassilana M, Arkowitz RA. Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth. Nat Microbiol. 2026 Jan; 11(1):169-179.

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Susorov D, Miscicka A, Golovenko D, Loveland AB, Zinoviev A, Pestova TV, Korostelev AA. Structural mechanism of mRNA decoding by mammalian GTPase GTPBP1. Nat Commun. 2025 Dec 05; 17(1):148.

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Kim H, Spangler CJ, Matsui A, Elferich J, Kim J, Roseborough A, Nyman M, Lahtinen TM, Gouaux E. Dimeric gold nanoparticles enable multiplexed labeling in cryoelectron tomography. Proc Natl Acad Sci U S A. 2025 Dec 02; 122(48):e2524034122.

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Yu C, Wang C, Forman T, Xie J, Major S, Fang MX, Voyer JE, Pogliano J, Fu TM. Phage SSB detection by retron Eco8 msDNA unleashes nuclease-mediated immunity. Mol Cell. 2025 Nov 20; 85(22):4243-4253.e4.

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Wang C, Rish AD, Armbruster EG, Xie J, Loveland AB, Shen Z, Gu B, Korostelev AA, Pogliano J, Fu TM. Disassembly activates Retron-Septu for antiphage defense. Science. 2025 Aug 21; 389(6762):eadv3344.

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?rd M, Winters MJ, Subbanna MS, de Mart?n Garrido N, Cushing VI, Kliche J, Benz C, Ivarsson Y, Greber BJ, Pryciak PM, Davey NE. High-throughput investigation of cyclin docking interactions reveals the complexity of motif binding determinants. Nat Commun. 2025 Aug 15; 16(1):7622.

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Skorupka KA, Matsuoka K, Hassan B, Ghirlando R, Balachandran V, Chen TH, Walters KJ, Schiffer CA, Wolf M, Iwatani Y, Matsuo H. HIV-1 vif mediates ubiquitination of the proximal protomer in the APOBEC3H dimer to induce degradation. Nat Commun. 2025 Jul 01; 16(1):5879.

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Elferich J, Kaminek M, Kong L, Odriozola A, Kukulski W, Zuber B, Grigorieff N. In situ high-resolution cryo-EM reconstructions from CEMOVIS. IUCrJ. 2025 Jul 01; 12(Pt 4):502-510.

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Ling X, Golovenko D, Gan J, Ma J, Korostelev AA, Fang W. Cryo-EM structure of a natural RNA nanocage. Nature. 2025 08; 644(8078):1107-1115.

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Dingeldein L, Silva-S?nchez D, Evans L, D'Imprima E, Grigorieff N, Covino R, Cossio P. Amortized template matching of molecular conformations from cryoelectron microscopy images using simulation-based inference. Proc Natl Acad Sci U S A. 2025 Jun 10; 122(23):e2420158122.

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