"Complement C9" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections.
- Complement C9
- C9, Complement
- Complement 9
- Complement Component 9
- Component 9, Complement
- C9 Complement
- Complement, C9
Below are MeSH descriptors whose meaning is more general than "Complement C9".
Below are MeSH descriptors whose meaning is more specific than "Complement C9".
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