Peptide Elongation Factor G
"Peptide Elongation Factor G" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptide Elongation Factor G catalyzes the translocation of peptidyl-tRNA from the A to the P site of bacterial ribosomes by a process linked to hydrolysis of GTP to GDP.
| Descriptor ID |
D020653
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| MeSH Number(s) |
D08.811.277.040.330.300.100.200 D12.776.157.325.150.200 D12.776.835.700.350.200
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Peptide Elongation Factor G".
Below are MeSH descriptors whose meaning is more specific than "Peptide Elongation Factor G".
This graph shows the total number of publications written about "Peptide Elongation Factor G" by people in this website by year, and whether "Peptide Elongation Factor G" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Peptide Elongation Factor G" by people in Profiles.
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Carbone CE, Loveland AB, Gamper HB, Hou YM, Demo G, Korostelev AA. Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun. 2021 12 13; 12(1):7236.
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Demo G, Gamper HB, Loveland AB, Masuda I, Carbone CE, Svidritskiy E, Hou YM, Korostelev AA. Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation. Nat Commun. 2021 07 30; 12(1):4644.
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Tek A, Korostelev AA, Flores SC. MMB-GUI: a fast morphing method demonstrates a possible ribosomal tRNA translocation trajectory. Nucleic Acids Res. 2016 Jan 08; 44(1):95-105.
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Brilot AF, Korostelev AA, Ermolenko DN, Grigorieff N. Structure of the ribosome with elongation factor G trapped in the pretranslocation state. Proc Natl Acad Sci U S A. 2013 Dec 24; 110(52):20994-9.
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Munro JB, Wasserman MR, Altman RB, Wang L, Blanchard SC. Correlated conformational events in EF-G and the ribosome regulate translocation. Nat Struct Mol Biol. 2010 Dec; 17(12):1470-7.
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Munro JB, Altman RB, Tung CS, Sanbonmatsu KY, Blanchard SC. A fast dynamic mode of the EF-G-bound ribosome. EMBO J. 2010 Feb 17; 29(4):770-81.