Peptide Termination Factors
"Peptide Termination Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that are involved in the peptide chain termination reaction (PEPTIDE CHAIN TERMINATION, TRANSLATIONAL) on RIBOSOMES. They include codon-specific class-I release factors, which recognize stop signals (TERMINATOR CODON) in the MESSENGER RNA; and codon-nonspecific class-II release factors.
Descriptor ID |
D010454
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MeSH Number(s) |
D12.776.835.862
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Peptide Termination Factors".
Below are MeSH descriptors whose meaning is more specific than "Peptide Termination Factors".
This graph shows the total number of publications written about "Peptide Termination Factors" by people in this website by year, and whether "Peptide Termination Factors" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2008 | 1 | 1 | 2 |
2009 | 0 | 1 | 1 |
2010 | 1 | 0 | 1 |
2011 | 1 | 1 | 2 |
2012 | 1 | 0 | 1 |
2013 | 1 | 1 | 2 |
2016 | 0 | 1 | 1 |
2017 | 1 | 0 | 1 |
2018 | 2 | 1 | 3 |
2019 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Peptide Termination Factors" by people in Profiles.
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Mangkalaphiban K, He F, Ganesan R, Wu C, Baker R, Jacobson A. Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae. PLoS Genet. 2021 04; 17(4):e1009538.
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Susorov D, Egri S, Korostelev AA. Termi-Luc: a versatile assay to monitor full-protein release from ribosomes. RNA. 2020 12; 26(12):2044-2050.
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Svidritskiy E, Demo G, Loveland AB, Xu C, Korostelev AA. Extensive ribosome and RF2 rearrangements during translation termination. Elife. 2019 09 12; 8.
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Svidritskiy E, Demo G, Korostelev AA. Mechanism of premature translation termination on a sense codon. J Biol Chem. 2018 08 10; 293(32):12472-12479.
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Svidritskiy E, Korostelev AA. Conformational Control of Translation Termination on the 70S Ribosome. Structure. 2018 06 05; 26(6):821-828.e3.
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Svidritskiy E, Korostelev AA. Mechanism of Inhibition of Translation Termination by Blasticidin S. J Mol Biol. 2018 03 02; 430(5):591-593.
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Demo G, Svidritskiy E, Madireddy R, Diaz-Avalos R, Grant T, Grigorieff N, Sousa D, Korostelev AA. Mechanism of ribosome rescue by ArfA and RF2. Elife. 2017 03 16; 6.
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Svidritskiy E, Madireddy R, Korostelev AA. Structural Basis for Translation Termination on a Pseudouridylated Stop Codon. J Mol Biol. 2016 05 22; 428(10 Pt B):2228-36.
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Santos N, Zhu J, Donohue JP, Korostelev AA, Noller HF. Crystal structure of the 70S ribosome bound with the Q253P mutant form of release factor RF2. Structure. 2013 Jul 02; 21(7):1258-63.
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Kim HJ, Kim NC, Wang YD, Scarborough EA, Moore J, Diaz Z, MacLea KS, Freibaum B, Li S, Molliex A, Kanagaraj AP, Carter R, Boylan KB, Wojtas AM, Rademakers R, Pinkus JL, Greenberg SA, Trojanowski JQ, Traynor BJ, Smith BN, Topp S, Gkazi AS, Miller J, Shaw CE, Kottlors M, Kirschner J, Pestronk A, Li YR, Ford AF, Gitler AD, Benatar M, King OD, Kimonis VE, Ross ED, Weihl CC, Shorter J, Taylor JP. Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. Nature. 2013 Mar 28; 495(7442):467-73.