Potassium Channel Blockers
"Potassium Channel Blockers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.
| Descriptor ID |
D026902
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| MeSH Number(s) |
D27.505.519.562.500 D27.505.954.411.645
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Potassium Channel Blockers".
Below are MeSH descriptors whose meaning is more specific than "Potassium Channel Blockers".
This graph shows the total number of publications written about "Potassium Channel Blockers" by people in this website by year, and whether "Potassium Channel Blockers" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 0 | 3 |
| 1996 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 2 | 0 | 2 |
| 2006 | 0 | 2 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Potassium Channel Blockers" by people in Profiles.
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Serviente C, Berry CW, Kenney WL, Alexander LM. Healthy active older adults have enhanced K+ channel-dependent endothelial vasodilatory mechanisms. Am J Physiol Regul Integr Comp Physiol. 2020 07 01; 319(1):R19-R25.
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Hasegawa Y, Mao W, Saha S, Gunner G, Kolpakova J, Martin GE, Futai K. Luciferase shRNA Presents off-Target Effects on Voltage-Gated Ion Channels in Mouse Hippocampal Pyramidal Neurons. eNeuro. 2017 Sep-Oct; 4(5).
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Hassan Virk HU, Qureshi WT, Makkar N, Bastawrose J, Souvaliotis N, Aziz J, Aziz E. Short- and long-term clinical predictors of pharmacological cardioversion of persistent atrial fibrillation by dofetilide: A retrospective cohort study of 160 patients. Clin Cardiol. 2017 Jul; 40(7):474-479.
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Gokina NI, Bonev AD, Phillips J, Gokin AP, Veilleux K, Oppenheimer K, Goloman G. Impairment of IKCa channels contributes to uteroplacental endothelial dysfunction in rat diabetic pregnancy. Am J Physiol Heart Circ Physiol. 2015 Aug 15; 309(4):H592-604.
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Wright PD, Kanumilli S, Tickle D, Cartland J, Bouloc N, Dale T, Tresize DJ, McCloskey C, McCavera S, Blanks AM, Kettleborough C, Jerman JC. A High-Throughput Electrophysiology Assay Identifies Inhibitors of the Inwardly Rectifying Potassium Channel Kir7.1. J Biomol Screen. 2015 Jul; 20(6):739-47.
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Ji X, Martin GE. BK channels mediate dopamine inhibition of firing in a subpopulation of core nucleus accumbens medium spiny neurons. Brain Res. 2014 Nov 07; 1588:1-16.
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Ch?vez JC, de la Vega-Beltr?n JL, Escoffier J, Visconti PE, Trevi?o CL, Darszon A, Salkoff L, Santi CM. Ion permeabilities in mouse sperm reveal an external trigger for SLO3-dependent hyperpolarization. PLoS One. 2013; 8(4):e60578.
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Hua Z, Kobertz WR. Chemical derivatization and purification of peptide-toxins for probing ion channel complexes. Methods Mol Biol. 2013; 995:19-30.
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Lu JF, Li XY, Shen CH, Lu Y, Li Z, Ye ZG, Wang Q, Xia Q, Wang HP. [Partial endothelium-dependent vasorelaxation of crocetin and its mechanism]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2010 11; 39(6):559-65.
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Ahern CA, Kobertz WR. Chemical tools for K(+) channel biology. Biochemistry. 2009 Jan 27; 48(3):517-26.