nef Gene Products, Human Immunodeficiency Virus
"nef Gene Products, Human Immunodeficiency Virus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins encoded by the NEF GENES of the HUMAN IMMUNODEFICIENCY VIRUS.
| Descriptor ID |
D054311
|
| MeSH Number(s) |
D12.776.964.775.362.500 D12.776.964.775.562.760 D12.776.964.925.500.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "nef Gene Products, Human Immunodeficiency Virus".
Below are MeSH descriptors whose meaning is more specific than "nef Gene Products, Human Immunodeficiency Virus".
This graph shows the total number of publications written about "nef Gene Products, Human Immunodeficiency Virus" by people in this website by year, and whether "nef Gene Products, Human Immunodeficiency Virus" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "nef Gene Products, Human Immunodeficiency Virus" by people in Profiles.
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Olety B, Usami Y, Wu Y, Peters P, G?ttlinger H. AP-2 Adaptor Complex-Dependent Enhancement of HIV-1 Replication by Nef in the Absence of the Nef/AP-2 Targets SERINC5 and CD4. mBio. 2023 02 28; 14(1):e0338222.
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Wu Y, Olety B, Weiss ER, Popova E, Yamanaka H, G?ttlinger H. Potent Enhancement of HIV-1 Replication by Nef in the Absence of SERINC3 and SERINC5. mBio. 2019 06 11; 10(3).
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Brumme ZL, Sudderuddin H, Ziemniak C, Luzuriaga K, Jones BR, Joy JB, Cunningham CK, Greenough T, Persaud D. Genetic complexity in the replication-competent latent HIV reservoir increases with untreated infection duration in infected youth. AIDS. 2019 02 01; 33(2):211-218.
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Dai W, Usami Y, Wu Y, G?ttlinger H. A Long Cytoplasmic Loop Governs the Sensitivity of the Anti-viral Host Protein SERINC5 to HIV-1 Nef. Cell Rep. 2018 01 23; 22(4):869-875.
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Rosa A, Chande A, Ziglio S, De Sanctis V, Bertorelli R, Goh SL, McCauley SM, Nowosielska A, Antonarakis SE, Luban J, Santoni FA, Pizzato M. HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation. Nature. 2015 Oct 08; 526(7572):212-7.
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Usami Y, Wu Y, G?ttlinger HG. SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef. Nature. 2015 Oct 08; 526(7572):218-23.
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Usami Y, Popov S, G?ttlinger HG. The Nef-like effect of murine leukemia virus glycosylated gag on HIV-1 infectivity is mediated by its cytoplasmic domain and depends on the AP-2 adaptor complex. J Virol. 2014 Mar; 88(6):3443-54.
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Usami Y, G?ttlinger H. HIV-1 Nef responsiveness is determined by Env variable regions involved in trimer association and correlates with neutralization sensitivity. Cell Rep. 2013 Nov 14; 5(3):802-12.
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Lai RP, Yan J, Heeney J, McClure MO, G?ttlinger H, Luban J, Pizzato M. Nef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41. PLoS Pathog. 2011 Dec; 7(12):e1002442.
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Pizzato M, Popova E, G?ttlinger HG. Nef can enhance the infectivity of receptor-pseudotyped human immunodeficiency virus type 1 particles. J Virol. 2008 Nov; 82(21):10811-9.