Flavin-Adenine Dinucleotide
"Flavin-Adenine Dinucleotide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
| Descriptor ID |
D005182
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| MeSH Number(s) |
D03.633.100.733.315.650.249 D03.633.100.759.646.138.506 D03.633.300.507.650.249 D08.211.474.650.249 D13.695.667.138.506 D13.695.827.068.506 D23.767.405.650.249
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Flavin-Adenine Dinucleotide".
Below are MeSH descriptors whose meaning is more specific than "Flavin-Adenine Dinucleotide".
This graph shows the total number of publications written about "Flavin-Adenine Dinucleotide" by people in this website by year, and whether "Flavin-Adenine Dinucleotide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2021 | 0 | 3 | 3 |
| 2022 | 1 | 1 | 2 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Flavin-Adenine Dinucleotide" by people in Profiles.
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Nisco A, Tolomeo M, Scalise M, Zanier K, Barile M. Exploring the impact of flavin homeostasis on cancer cell metabolism. Biochim Biophys Acta Rev Cancer. 2024 09; 1879(5):189149.
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Leo G, Leone P, Ataie Kachoie E, Tolomeo M, Galluccio M, Indiveri C, Barile M, Capaldi S. Structural insights into the bifunctional enzyme human FAD synthase. Structure. 2024 Jul 11; 32(7):953-965.e5.
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Ben Mariem O, Saporiti S, Guerrini U, Laurenzi T, Palazzolo L, Indiveri C, Barile M, De Fabiani E, Eberini I. In silico investigation on structure-function relationship of members belonging to the human SLC52 transporter family. Proteins. 2023 05; 91(5):619-633.
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Tolomeo M, Chimienti G, Lanza M, Barbaro R, Nisco A, Latronico T, Leone P, Petrosillo G, Liuzzi GM, Ryder B, Inbar-Feigenberg M, Colella M, Lezza AMS, Olsen RKJ, Barile M. Retrograde response to mitochondrial dysfunctions associated to LOF variations in FLAD1 exon 2: unraveling the importance of RFVT2. Free Radic Res. 2022 Jul-Aug; 56(7-8):511-525.
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Leone P, Tolomeo M, Piancone E, Puzzovio PG, De Giorgi C, Indiveri C, Di Schiavi E, Barile M. Mimicking human riboflavin responsive neuromuscular disorders by silencing flad-1 gene in C. elegans: Alteration of vitamin transport and cholinergic transmission. IUBMB Life. 2022 07; 74(7):672-683.
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Leone P, Tolomeo M, Barile M. Continuous and Discontinuous Approaches to Study FAD Synthesis and Degradation Catalyzed by Purified Recombinant FAD Synthase or Cellular Fractions. Methods Mol Biol. 2021; 2280:87-116.
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Tolomeo M, Nisco A, Barile M. Alteration of Flavin Cofactor Homeostasis in Human Neuromuscular Pathologies. Methods Mol Biol. 2021; 2280:275-295.
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Carver GE, Locknar SA, Weaver DL, Stein JL, Stein GS. Real-time detection of breast cancer at the cellular level. J Cell Physiol. 2019 05; 234(5):5413-5419.
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Protchenko O, Rodriguez-Suarez R, Androphy R, Bussey H, Philpott CC. A screen for genes of heme uptake identifies the FLC family required for import of FAD into the endoplasmic reticulum. J Biol Chem. 2006 Jul 28; 281(30):21445-21457.
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Gray M, Goodman AJ, Carroll JB, Bardon K, Markey M, Cooke G, Rotello VM. Model systems for flavoenzyme activity: interplay of hydrogen bonding and aromatic stacking in cofactor redox modulation. Org Lett. 2004 Feb 05; 6(3):385-8.