Below are the most recent publications written about "Carcinoma, Pancreatic Ductal" by people in Profiles.
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Labadie BW, Obradovic A, Raufi AG, Wasko UN, Tomassoni L, Ge L, May M, Vij M, Li L, Ross I, Sedycius SS, Sender N, Dreher N, Wu L, Abuzaid S, Iuga A, Shah P, Wulfkuhle JD, Bates S, Wong W, Pellicciotta I, Lyashchenko AK, Safran H, Izar B, Petricoin EF, Cremers S, Tan AC, Lee S, Califano A, Olive KP, Manji GA. Targeting of MEK and Autophagy in Pancreatic Adenocarcinoma and Analysis of Treatment Sensitivity in Preclinical and Clinical Models: MEKiAUTO. JCO Precis Oncol. 2026 Jun; 10(6):e2600138.
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Clausen TM, Weiss RJ, Tremblay JR, Kellman BP, Coker J, Dworkin LA, Rodriguez JP, Chang IM, Chen T, Padala V, Karlsson R, Song H, Peck KL, Ogawa S, Sandoval DR, Joshi HJ, Wang G, Ferguson LP, Bhalerao N, Moores A, Reya T, Sander M, Caffrey TC, Grem JL, Aicher A, Heeschen C, Le D, Lewis NE, Hollingsworth MA, Grandgenett PM, Bellis SL, Miller RL, Fuster MM, Dawson DW, Engle DD, Esko JD. Antithrombin-binding heparan sulfate is ubiquitously expressed in epithelial cells and suppresses pancreatic tumorigenesis. J Clin Invest. 2025 11 17; 135(22).
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Peura J, Johnson C, Pitarresi JR. To EMT or Not to EMT: Ablation of Mesenchymal Tumor Cell Lineages Reveals the Essential Role of EMT in Pancreatic Cancer Initiation and Evolution. Cancer Res. 2025 Jun 16; 85(12):2146-2148.
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Weissenrieder JS, Peura J, Paudel U, Bhalerao N, Weinmann N, Johnson C, Wengyn M, Drager R, Furth EE, Simin K, Ruscetti M, Stanger BZ, Rustgi AK, Pitarresi JR, Foskett JK. Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity. Cell Rep. 2025 May 27; 44(5):115627.
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Nisco A, Sposato A, Ardone M, Leone P, Cardone RA, Console L, Indiveri C, Zanier K, Barile M. Supplying LSD1 with FAD in pancreatic cancer: A matter of protein-protein interaction? Arch Biochem Biophys. 2025 02; 764:110291.
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Struth E, Labaf M, Karimnia V, Liu Y, Cramer G, Dahl JB, Slack FJ, Zarringhalam K, Celli JP. Drug resistant pancreatic cancer cells exhibit altered biophysical interactions with stromal fibroblasts in imaging studies of 3D co-culture models. Sci Rep. 2024 09 05; 14(1):20698.
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Delgado-Coka LA, Roa-Pe?a L, Babu S, Horowitz M, Petricoin EF, Matrisian LM, Blais EM, Marchenko N, Allard FD, Akalin A, Jiang W, Larson BK, Hendifar AE, Picozzi VJ, Choi M, Shroyer KR, Escobar-Hoyos LF. Keratin 17 is a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma. Am J Clin Pathol. 2024 09 03; 162(3):314-326.
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Chibaya L, DeMarco KD, Lusi CF, Kane GI, Brassil ML, Parikh CN, Murphy KC, Chowdhury SR, Li J, Ma B, Naylor TE, Cerrutti J, Mori H, Diaz-Infante M, Peura J, Pitarresi JR, Zhu LJ, Fitzgerald KA, Atukorale PU, Ruscetti M. Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer. Sci Transl Med. 2024 08 28; 16(762):eadj9366.
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Li AL, Sugiura K, Nishiwaki N, Suzuki K, Sadeghian D, Zhao J, Maitra A, Falvo D, Chandwani R, Pitarresi JR, Sims PA, Rustgi AK. FRA1 controls acinar cell plasticity during murine KrasG12D-induced pancreatic acinar to ductal metaplasia. Dev Cell. 2024 11 18; 59(22):3025-3042.e7.
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Assouline B, Kahn R, Hodali L, Condiotti R, Engel Y, Elyada E, Mordechai-Heyn T, Pitarresi JR, Atias D, Steinberg E, Bidany-Mizrahi T, Forkosh E, Katz LH, Benny O, Golan T, Hofree M, Stewart SA, Atlan KA, Zamir G, Stanger BZ, Berger M, Ben-Porath I. Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma restrict CD8+ T cell activation and limit responsiveness to immunotherapy in mice. Nat Commun. 2024 Jul 22; 15(1):6162.