"Factor V" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.
| Descriptor ID |
D005165
|
| MeSH Number(s) |
D12.776.124.125.300 D23.119.300
|
| Concept/Terms |
Factor V- Factor V
- Factor Five
- Five, Factor
- AC Globulin
- Blood Coagulation Factor V
- Factor Pi
- Proaccelerin
- Factor 5
- Coagulation Factor V
- Factor V, Coagulation
|
Below are MeSH descriptors whose meaning is more general than "Factor V".
Below are MeSH descriptors whose meaning is more specific than "Factor V".
This graph shows the total number of publications written about "Factor V" by people in this website by year, and whether "Factor V" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Factor V" by people in Profiles.
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Fraielli K, Patel D, Wang D, Sargent K, Gore J. Successful use of fondaparinux in the setting of heparin-induced thrombocytopenia with thrombosis confirmed by serotonin-release assay and Factor V Leiden. J Clin Pharm Ther. 2019 Oct; 44(5):809-812.
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Herskovits AZ, Morgan EA, Lemire SJ, Lindeman NI, Dorfman DM. An improved algorithm for activated protein C resistance and factor V Leiden screening. Am J Clin Pathol. 2013 Sep; 140(3):379-86.
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Haapaniemi E, Helenius J, Jakovljevic D, Soinne L, Syrj?l? M, Kaste M, Lassila R, Tatlisumak T. Ischaemic stroke patients with heterozygous factor V Leiden present with multiple brain infarctions and widespread atherothrombotic disease. Thromb Haemost. 2009 Jan; 101(1):145-50.
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Bednarek FJ, Bean S, Barnard MR, Frelinger AL, Michelson AD. The platelet hyporeactivity of extremely low birth weight neonates is age-dependent. Thromb Res. 2009 May; 124(1):42-5.
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Hirbawi J, Bukys MA, Barhoover MA, Erdogan E, Kalafatis M. Role of the acidic hirudin-like COOH-terminal amino acid region of factor Va heavy chain in the enhanced function of prothrombinase. Biochemistry. 2008 Jul 29; 47(30):7963-74.
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Leung R, Gwozdz AM, Wang H, Bang KW, Packham MA, Freedman J, Rand ML. Persistence of procoagulant surface expression on activated human platelets: involvement of apoptosis and aminophospholipid translocase activity. J Thromb Haemost. 2007 Mar; 5(3):560-70.
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D?nmez Y, Kanadasi M, Tanriverdi K, Demir M, Demirtas M, Cayli M, Alhan C, Baslamisli F. Prothrombin 20210GA and factor V Leiden mutations in patients less than 55 years old with myocardial infarction. Jpn Heart J. 2004 May; 45(3):505-12.
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Burkman RT. Venous thromboembolism and oral contraceptives: current status and clinical implications. Treat Endocrinol. 2002; 1(3):143-7.
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Furman MI, Krueger LA, Frelinger AL, Barnard MR, Mascelli MA, Nakada MT, Michelson AD. GPIIb-IIIa antagonist-induced reduction in platelet surface factor V/Va binding and phosphatidylserine expression in whole blood. Thromb Haemost. 2000 Sep; 84(3):492-8.