Chromosomes, Human, Pair 21

"Chromosomes, Human, Pair 21" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A specific pair of GROUP G CHROMOSOMES of the human chromosome classification.

Descriptor ID	D002891
MeSH Number(s)	A11.284.187.520.300.505.510 G05.360.162.520.300.505.510
Concept/Terms	Chromosomes, Human, Pair 21 Chromosomes, Human, Pair 21 Chromosome 21

Below are MeSH descriptors whose meaning is more general than "Chromosomes, Human, Pair 21".

Anatomy [A]
Cells [A11]
Cellular Structures [A11.284]
Chromosomes [A11.284.187]
Chromosomes, Mammalian [A11.284.187.520]
Chromosomes, Human [A11.284.187.520.300]
Chromosomes, Human, 21-22 and Y [A11.284.187.520.300.505]
Chromosomes, Human, Pair 21 [A11.284.187.520.300.505.510]
Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Chromosomes [G05.360.162]
Chromosomes, Mammalian [G05.360.162.520]
Chromosomes, Human [G05.360.162.520.300]
Chromosomes, Human, 21-22 and Y [G05.360.162.520.300.505]
Chromosomes, Human, Pair 21 [G05.360.162.520.300.505.510]

Below are MeSH descriptors whose meaning is related to "Chromosomes, Human, Pair 21".

Below are MeSH descriptors whose meaning is more specific than "Chromosomes, Human, Pair 21".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Chromosomes, Human, Pair 21" by people in this website by year, and whether "Chromosomes, Human, Pair 21" was a major or minor topic of these publications.

Bar chart showing 21 publications over 14 distinct years, with a maximum of 3 publications in 2002 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1998	1	0	1
2002	2	1	3
2005	1	0	1
2006	0	1	1
2008	1	0	1
2009	1	1	2
2011	1	0	1
2012	1	1	2
2013	2	1	3
2015	0	2	2
2016	1	0	1
2017	0	1	1
2018	0	1	1

Below are the most recent publications written about "Chromosomes, Human, Pair 21" by people in Profiles.

Chiang JC, Jiang J, Newburger PE, Lawrence JB. Trisomy silencing by XIST normalizes Down syndrome cell pathogenesis demonstrated for hematopoietic defects in vitro. Nat Commun. 2018 12 05; 9(1):5180.

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Zaidi SK, Perez AW, White ES, Lian JB, Stein JL, Stein GS. An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells. Oncotarget. 2017 Jun 20; 8(25):39994-40005.

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Ziccardi W, Zhao C, Shepelev V, Uralsky L, Alexandrov I, Andreeva T, Rogaev E, Bun C, Miller E, Putonti C, Doering J. Clusters of alpha satellite on human chromosome 21 are dispersed far onto the short arm and lack ancient layers. Chromosome Res. 2016 09; 24(3):421-36.

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Mendioroz M, Do C, Jiang X, Liu C, Darbary HK, Lang CF, Lin J, Thomas A, Abu-Amero S, Stanier P, Temkin A, Yale A, Liu MM, Li Y, Salas M, Kerkel K, Capone G, Silverman W, Yu YE, Moore G, Wegiel J, Tycko B. Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models. Genome Biol. 2015 Nov 25; 16:263.

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Trombly DJ, Whitfield TW, Padmanabhan S, Gordon JA, Lian JB, van Wijnen AJ, Zaidi SK, Stein JL, Stein GS. Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells. BMC Genomics. 2015 Apr 17; 16:309.

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Lawrence J, Telfer C. Interview: from Down's syndrome to basic epigenetics and back again. Epigenomics. 2013 Dec; 5(6):611-4.

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Naumova N, Imakaev M, Fudenberg G, Zhan Y, Lajoie BR, Mirny LA, Dekker J. Organization of the mitotic chromosome. Science. 2013 Nov 22; 342(6161):948-53.

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Stuardo M, Nicovani S, Javed A, Gutierrez S. Breakpoint regions of ETO gene involved in (8; 21) leukemic translocations are enriched in acetylated histone H3. J Cell Biochem. 2013 Nov; 114(11):2569-76.

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Jiang J, Jing Y, Cost GJ, Chiang JC, Kolpa HJ, Cotton AM, Carone DM, Carone BR, Shivak DA, Guschin DY, Pearl JR, Rebar EJ, Byron M, Gregory PD, Brown CJ, Urnov FD, Hall LL, Lawrence JB. Translating dosage compensation to trisomy 21. Nature. 2013 Aug 15; 500(7462):296-300.

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Pulikkan JA, Madera D, Xue L, Bradley P, Landrette SF, Kuo YH, Abbas S, Zhu LJ, Valk P, Castilla LH. Thrombopoietin/MPL participates in initiating and maintaining RUNX1-ETO acute myeloid leukemia via PI3K/AKT signaling. Blood. 2012 Jul 26; 120(4):868-79.

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