 CD4-Positive T-Lymphocytes
"CD4-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.
| Descriptor ID |
D015496
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| MeSH Number(s) |
A11.118.637.555.567.569.200 A15.145.229.637.555.567.569.200 A15.382.490.555.567.569.200
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| Concept/Terms |
CD4-Positive T-Lymphocytes- CD4-Positive T-Lymphocytes
- CD4 Positive T Lymphocytes
- CD4-Positive T-Lymphocyte
- T-Lymphocyte, CD4-Positive
- T-Lymphocytes, CD4-Positive
- T4 Cells
- T4 Cell
- T4 Lymphocytes
- T4 Lymphocyte
- CD4-Positive Lymphocytes
- CD4-Positive Lymphocyte
- Lymphocyte, CD4-Positive
- Lymphocytes, CD4-Positive
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Below are MeSH descriptors whose meaning is more general than "CD4-Positive T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "CD4-Positive T-Lymphocytes".
This graph shows the total number of publications written about "CD4-Positive T-Lymphocytes" by people in this website by year, and whether "CD4-Positive T-Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1989 | 0 | 1 | 1 | | 1990 | 2 | 0 | 2 | | 1991 | 2 | 3 | 5 | | 1992 | 4 | 1 | 5 | | 1993 | 4 | 5 | 9 | | 1994 | 8 | 6 | 14 | | 1995 | 3 | 6 | 9 | | 1996 | 5 | 4 | 9 | | 1997 | 8 | 3 | 11 | | 1998 | 4 | 3 | 7 | | 1999 | 3 | 3 | 6 | | 2000 | 8 | 2 | 10 | | 2001 | 3 | 10 | 13 | | 2002 | 10 | 6 | 16 | | 2003 | 12 | 2 | 14 | | 2004 | 9 | 5 | 14 | | 2005 | 16 | 9 | 25 | | 2006 | 10 | 13 | 23 | | 2007 | 12 | 15 | 27 | | 2008 | 15 | 11 | 26 | | 2009 | 13 | 8 | 21 | | 2010 | 15 | 7 | 22 | | 2011 | 11 | 7 | 18 | | 2012 | 17 | 10 | 27 | | 2013 | 13 | 8 | 21 | | 2014 | 9 | 5 | 14 | | 2015 | 6 | 7 | 13 | | 2016 | 4 | 0 | 4 | | 2017 | 2 | 3 | 5 | | 2018 | 2 | 0 | 2 |
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Below are the most recent publications written about "CD4-Positive T-Lymphocytes" by people in Profiles.
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Hatfield SD, Daniels KA, O'Donnell CL, Waggoner SN, Welsh RM. Weak vaccinia virus-induced NK cell regulation of CD4 T cells is associated with reduced NK cell differentiation and cytolytic activity. Virology. 2018 06; 519:131-144.
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Silveira GF, Wowk PF, Cataneo AHD, Dos Santos PF, Delgobo M, Stimamiglio MA, Lo Sarzi M, Thomazelli APFS, Conchon-Costa I, Pavanelli WR, Antonelli LRV, Báfica A, Mansur DS, Dos Santos CND, Bordignon J. Human T Lymphocytes Are Permissive for Dengue Virus Replication. J Virol. 2018 05 15; 92(10).
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Carpenter SM, Yang JD, Lee J, Barreira-Silva P, Behar SM. Vaccine-elicited memory CD4+ T cell expansion is impaired in the lungs during tuberculosis. PLoS Pathog. 2017 Nov; 13(11):e1006704.
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Rothchild AC, Stowell B, Goyal G, Nunes-Alves C, Yang Q, Papavinasasundaram K, Sassetti CM, Dranoff G, Chen X, Lee J, Behar SM. Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during Mycobacterium tuberculosis Infection. MBio. 2017 10 24; 8(5).
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Platt CD, Fried AJ, Hoyos-Bachiloglu R, Usmani GN, Schmidt B, Whangbo J, Chiarle R, Chou J, Geha RS. Combined immunodeficiency with EBV positive B cell lymphoma and epidermodysplasia verruciformis due to a novel homozygous mutation in RASGRP1. Clin Immunol. 2017 10; 183:142-144.
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Swain SL, Kugler-Umana O, Kuang Y, Zhang W. The properties of the unique age-associated B cell subset reveal a shift in strategy of immune response with age. Cell Immunol. 2017 Nov; 321:52-60.
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Rainwater-Lovett K, Ziemniak C, Watson D, Luzuriaga K, Siberry G, Petru A, Chen Y, Uprety P, McManus M, Ho YC, Lamers SL, Persaud D. Paucity of Intact Non-Induced Provirus with Early, Long-Term Antiretroviral Therapy of Perinatal HIV Infection. PLoS One. 2017; 12(2):e0170548.
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Passos LS, Villani FN, Magalhães LM, Gollob KJ, Antonelli LR, Nunes MC, Dutra WO. Blocking of CD1d Decreases Trypanosoma cruzi-Induced Activation of CD4-CD8- T Cells and Modulates the Inflammatory Response in Patients With Chagas Heart Disease. J Infect Dis. 2016 09 15; 214(6):935-44.
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Delong T, Wiles TA, Baker RL, Bradley B, Barbour G, Reisdorph R, Armstrong M, Powell RL, Reisdorph N, Kumar N, Elso CM, DeNicola M, Bottino R, Powers AC, Harlan DM, Kent SC, Mannering SI, Haskins K. Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion. Science. 2016 Feb 12; 351(6274):711-4.
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Campi-Azevedo AC, Costa-Pereira C, Antonelli LR, Fonseca CT, Teixeira-Carvalho A, Villela-Rezende G, Santos RA, Batista MA, Campos FM, Pacheco-Porto L, Melo Júnior OA, Hossell DM, Coelho-dos-Reis JG, Peruhype-Magalhães V, Costa-Silva MF, de Oliveira JG, Farias RH, Noronha TG, Lemos JA, von Doellinger Vdos R, Simões M, de Souza MM, Malaquias LC, Persi HR, Pereira JM, Martins JA, Dornelas-Ribeiro M, Vinhas Ade A, Alves TR, Maia Mde L, Freire Mda S, Martins Rde M, Homma A, Romano AP, Domingues CM, Tauil PL, Vasconcelos PF, Rios M, Caldas IR, Camacho LA, Martins-Filho OA. Booster dose after 10 years is recommended following 17DD-YF primary vaccination. Hum Vaccin Immunother. 2016; 12(2):491-502.
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