Digoxin
"Digoxin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
Descriptor ID |
D004077
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MeSH Number(s) |
D04.808.155.160.349 D04.808.155.580.130.500.436 D09.408.180.261.436
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Concept/Terms |
Digacin- Digacin
- Lilly Brand of Digoxin
Digitek- Digitek
- Bertek Brand of Digoxin
- UDL Brand of Digoxin
Lanoxin- Lanoxin
- Glaxo Wellcome Brand of Digoxin
- GlaxoSmithKline Brand 1 of Digoxin
- Virco Brand of Digoxin
- Lanoxin-PG
- Lanoxin PG
- Lenoxin
Digoxine Nativelle- Digoxine Nativelle
- Nativelle, Digoxine
- Hemigoxine Nativelle
- Nativelle, Hemigoxine
- Proctor & Gamble Brand of Digoxin
Dilanacin- Dilanacin
- AWD.pharma Brand of Digoxin
Lanicor- Lanicor
- Teofarma Brand of Digoxin
Lanoxicaps- Lanoxicaps
- GlaxoSmithKline Brand 2 of Digoxin
Mapluxin- Mapluxin
- Novartis Brand of Digoxin
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Below are MeSH descriptors whose meaning is more general than "Digoxin".
Below are MeSH descriptors whose meaning is more specific than "Digoxin".
This graph shows the total number of publications written about "Digoxin" by people in this website by year, and whether "Digoxin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 | 2000 | 2 | 0 | 2 | 2004 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2015 | 1 | 0 | 1 | 2016 | 2 | 0 | 2 |
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Below are the most recent publications written about "Digoxin" by people in Profiles.
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Al-Khateeb M, Qureshi WT, Odeh R, Ahmed AM, Sakr S, Elshawi R, Bdeir MB, Al-Mallah MH. The impact of digoxin on mortality in patients with chronic systolic heart failure: A propensity-matched cohort study. Int J Cardiol. 2017 Feb 01; 228:214-218.
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Qureshi W, O'Neal WT, Soliman EZ, Al-Mallah MH. Systematic review and meta-analysis of mortality and digoxin use in atrial fibrillation. Cardiol J. 2016; 23(3):333-43.
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Temtanakitpaisan Y, Kilari S, Damrongwatanasuk R. Use of digoxin in chronic systolic heart failure in current era. Am J Med. 2015 Jan; 128(1):e17.
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Sanghavi DM. A novel method of fetal cardioversion. Pediatr Cardiol. 2013 Mar; 34(3):700-1.
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Huh JR, Leung MW, Huang P, Ryan DA, Krout MR, Malapaka RR, Chow J, Manel N, Ciofani M, Kim SV, Cuesta A, Santori FR, Lafaille JJ, Xu HE, Gin DY, Rastinejad F, Littman DR. Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing ROR?t activity. Nature. 2011 Apr 28; 472(7344):486-90.
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Leonard CE, Haynes K, Localio AR, Hennessy S, Tjia J, Cohen A, Kimmel SE, Feldman HI, Metlay JP. Diagnostic E-codes for commonly used, narrow therapeutic index medications poorly predict adverse drug events. J Clin Epidemiol. 2008 Jun; 61(6):561-71.
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Bauer A, McDonald AD, Nasir K, Peller L, Rade JJ, Miller JM, Heldman AW, Donahue JK. Inhibitory G protein overexpression provides physiologically relevant heart rate control in persistent atrial fibrillation. Circulation. 2004 Nov 9; 110(19):3115-20.
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Spodick DH. Well concealed atrial tachycardia with Wenckebach (Mobitz I) atrioventricular block: digitalis toxicity. Am J Geriatr Cardiol. 2001 Jan-Feb; 10(1):59.
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Gambassi G, Lapane KL, Sgadari A, Carbonin P, Gatsonis C, Lipsitz LA, Mor V, Bernabei R. Effects of angiotensin-converting enzyme inhibitors and digoxin on health outcomes of very old patients with heart failure. SAGE Study Group. Systematic Assessment of Geriatric drug use via Epidemiology. Arch Intern Med. 2000 Jan 10; 160(1):53-60.
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Gambassi G, Forman DE, Lapane KL, Mor V, Sgadari A, Lipsitz LA, Bernabei R. Management of heart failure among very old persons living in long-term care: has the voice of trials spread? The SAGE Study Group. Am Heart J. 2000 Jan; 139(1 Pt 1):85-93.
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