"Enteric Nervous System" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation. (From Kandel, Schwartz, and Jessel, Principles of Neural Science, 3d ed, p766)
Descriptor ID |
D017615
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MeSH Number(s) |
A08.800.050.150
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Concept/Terms |
Enteric Nervous System- Enteric Nervous System
- Enteric Nervous Systems
- Nervous System, Enteric
- Nervous Systems, Enteric
- System, Enteric Nervous
- Systems, Enteric Nervous
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Below are MeSH descriptors whose meaning is more general than "Enteric Nervous System".
Below are MeSH descriptors whose meaning is more specific than "Enteric Nervous System".
This graph shows the total number of publications written about "Enteric Nervous System" by people in this website by year, and whether "Enteric Nervous System" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Enteric Nervous System" by people in Profiles.
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Kulkarni S, Ganz J, Bayrer J, Becker L, Bogunovic M, Rao M. Advances in Enteric Neurobiology: The "Brain" in the Gut in Health and Disease. J Neurosci. 2018 10 31; 38(44):9346-9354.
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Gombash SE, Cowley CJ, Fitzgerald JA, Lepak CA, Neides MG, Hook K, Todd LJ, Wang GD, Mueller C, Kaspar BK, Bielefeld EC, Fischer AJ, Wood JD, Foust KD. Systemic gene delivery transduces the enteric nervous system of guinea pigs and cynomolgus macaques. Gene Ther. 2017 10; 24(10):640-648.
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Kulkarni S, Micci MA, Leser J, Shin C, Tang SC, Fu YY, Liu L, Li Q, Saha M, Li C, Enikolopov G, Becker L, Rakhilin N, Anderson M, Shen X, Dong X, Butte MJ, Song H, Southard-Smith EM, Kapur RP, Bogunovic M, Pasricha PJ. Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis. Proc Natl Acad Sci U S A. 2017 05 02; 114(18):E3709-E3718.
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Shea-Donohue T, Urban JF. Neuroimmune Modulation of Gut Function. Handb Exp Pharmacol. 2017; 239:247-267.
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Benskey MJ, Kuhn NC, Galligan JJ, Garcia J, Boye SE, Hauswirth WW, Mueller C, Boye SL, Manfredsson FP. Targeted gene delivery to the enteric nervous system using AAV: a comparison across serotypes and capsid mutants. Mol Ther. 2015 Mar; 23(3):488-500.
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Shea-Donohue T, Notari L, Stiltz J, Sun R, Madden KB, Urban JF, Zhao A. Role of enteric nerves in immune-mediated changes in protease-activated receptor 2 effects on gut function. Neurogastroenterol Motil. 2010 Oct; 22(10):1138-e291.
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Karim S, Hession C, Marconi S, Gang DL, Otis CN. The identification of ganglion cells in Hirschsprung disease by the immunohistochemical detection of ret oncoprotein. Am J Clin Pathol. 2006 Jul; 126(1):49-54.
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Zhao A, McDermott J, Urban JF, Gause W, Madden KB, Yeung KA, Morris SC, Finkelman FD, Shea-Donohue T. Dependence of IL-4, IL-13, and nematode-induced alterations in murine small intestinal smooth muscle contractility on Stat6 and enteric nerves. J Immunol. 2003 Jul 15; 171(2):948-54.