"Protein Conformation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
| Descriptor ID |
D011487
|
| MeSH Number(s) |
G02.111.570.820.709
|
| Concept/Terms |
Protein Conformation- Protein Conformation
- Conformation, Protein
- Conformations, Protein
- Protein Conformations
|
Below are MeSH descriptors whose meaning is more general than "Protein Conformation".
Below are MeSH descriptors whose meaning is more specific than "Protein Conformation".
This graph shows the total number of publications written about "Protein Conformation" by people in this website by year, and whether "Protein Conformation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 9 | 9 |
| 1997 | 1 | 6 | 7 |
| 1998 | 2 | 9 | 11 |
| 1999 | 4 | 7 | 11 |
| 2000 | 2 | 13 | 15 |
| 2001 | 1 | 11 | 12 |
| 2002 | 2 | 17 | 19 |
| 2003 | 4 | 26 | 30 |
| 2004 | 0 | 30 | 30 |
| 2005 | 2 | 21 | 23 |
| 2006 | 3 | 27 | 30 |
| 2007 | 0 | 22 | 22 |
| 2008 | 0 | 24 | 24 |
| 2009 | 6 | 30 | 36 |
| 2010 | 2 | 16 | 18 |
| 2011 | 2 | 25 | 27 |
| 2012 | 0 | 29 | 29 |
| 2013 | 2 | 20 | 22 |
| 2014 | 1 | 27 | 28 |
| 2015 | 1 | 25 | 26 |
| 2016 | 0 | 16 | 16 |
| 2017 | 0 | 14 | 14 |
| 2018 | 5 | 34 | 39 |
| 2019 | 1 | 23 | 24 |
| 2020 | 3 | 14 | 17 |
| 2021 | 1 | 21 | 22 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 3 | 3 |
| 2024 | 0 | 8 | 8 |
| 2025 | 1 | 9 | 10 |
| 2026 | 0 | 4 | 4 |
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Below are the most recent publications written about "Protein Conformation" by people in Profiles.
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Unger M, Munro JB. Control of viral envelope glycoprotein function revealed by single-molecule imaging. Curr Opin Struct Biol. 2026 Jun; 98:103275.
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Somavarapu AK, Ge J, Yengo CM, Craig R, Padron R. Cryo-EM reveals how cardiomyopathy therapeutic drugs modulate the myosin motors of the heart. Sci Adv. 2026 May; 12(18):eaed6472.
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Nachum GS, Boucher JI, Flynn JM, Quansah P, Nachum S, Bolon DNA. Mutational scan of self-cleavage by HIV-1 protease provides new views of a conformationally dynamic mechanism. J Virol. 2026 Apr 21; 100(4):e0222925.
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Xie H, Zhao W, Xiao H, Zhang Y, Shen Y, Gan Y, Tong Q, Zhao Y, Tan H, Yang J. In Situ Structure Determination of a Membrane Protein in E. coli Cellular Membranes by Proton-Detected Solid-State NMR. J Am Chem Soc. 2026 03 11; 148(9):9433-9448.
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Smith AJ, Rahat MA, Scaramozza LJ, Eyles SJ, Hardy JA. Inhibition of Zika Virus Protease by Modulating NS2B-NS3 Interactions. Biochemistry. 2026 01 06; 65(1):64-76.
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D?az-Salinas MA, Benlarbi M, Chatterjee D, Nayrac M, Robidas M, Pinyakorn S, Phanuphak N, Sacdalan C, Medjahed H, Pr?vost J, Trautmann L, Pazgier M, Finzi A, Munro JB. Conformational dynamics of the HIV-1 envelope glycoprotein from CRF01_AE is associated with susceptibility to antibody-dependent cellular cytotoxicity. J Virol. 2026 01 20; 100(1):e0166725.
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Kuzio NJ, Tonelli M, Fejzo J, Hardy JA. An NMR sample preparation case study: Considerations for the self-destructive protease caspase-6. PLoS One. 2025; 20(11):e0337291.
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Doxsey DD, Shen K. Global conformation of the Rag GTPase heterodimer governs eukaryotic amino acid sensing. Proc Natl Acad Sci U S A. 2025 Oct 21; 122(42):e2517050122.
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Nguyen BV, ?zden C, Dong K, Koc OC, Torres-Ocampo AP, Dziedzic N, Flaherty D, Huang J, Sankara S, Abromson NL, Tomchick DR, Fissore RA, Chen J, Garman SC, Stratton MM. A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation. Nat Commun. 2025 Sep 26; 16(1):8461.
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Bhat YA, Bhat JY, Shiek SA, Dar MA, Amin S, Peterson CL, Udgaonkar JB, Wani AH. Dynamic Conformations of Chromatin Remodeler ISWI during Nucleosome Sliding Revealed by Hydrogen-Deuterium Exchange Coupled to Mass Spectrometry. Biochemistry. 2025 10 07; 64(19):4155-4169.