Histiocytosis, Langerhans-Cell
"Histiocytosis, Langerhans-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.
Descriptor ID |
D006646
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MeSH Number(s) |
C08.381.483.375 C15.604.250.400
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Concept/Terms |
Histiocytosis, Langerhans-Cell- Histiocytosis, Langerhans-Cell
- Histiocytosis, Langerhans Cell
- Hand-Schueller-Christian Syndrome
- Hand Schueller Christian Syndrome
- Syndrome, Hand-Schueller-Christian
- Hand-Schüller-Christian Disease
- Disease, Hand-Schüller-Christian
- Hand Schüller Christian Disease
- Hand-Schüller-Christian Syndrome
- Hand Schüller Christian Syndrome
- Syndrome, Hand-Schüller-Christian
- Histiocytosis X
- Histiocytosis, Generalized
- Generalized Histiocytoses
- Generalized Histiocytosis
- Histiocytoses, Generalized
- Histiocytosis-X
- Langerhans Cell Histiocytosis
- Cell Histiocytoses, Langerhans
- Cell Histiocytosis, Langerhans
- Histiocytoses, Langerhans Cell
- Langerhans Cell Histiocytoses
- Langerhans-Cell Granulomatosis
- Granulomatosis, Langerhans-Cell
- Langerhans-Cell Histiocytosis
- Letterer-Siwe Disease
- Disease, Letterer-Siwe
- Letterer Siwe Disease
- Non-Lipid Reticuloendotheliosis
- Non Lipid Reticuloendotheliosis
- Non-Lipid Reticuloendothelioses
- Reticuloendothelioses, Non-Lipid
- Reticuloendotheliosis, Non-Lipid
- Schueller-Christian Disease
- Disease, Schueller-Christian
- Schueller Christian Disease
- Systemic Aleukemic Reticuloendotheliosis
- Aleukemic Reticuloendothelioses, Systemic
- Aleukemic Reticuloendotheliosis, Systemic
- Reticuloendothelioses, Systemic Aleukemic
- Reticuloendotheliosis, Systemic Aleukemic
- Systemic Aleukemic Reticuloendothelioses
- Type 2 Histiocytosis
- Histiocytoses, Type 2
- Histiocytosis, Type 2
- Type 2 Histiocytoses
- Langerhans Cell Granulomatosis
- Cell Granulomatoses, Langerhans
- Cell Granulomatosis, Langerhans
- Granulomatoses, Langerhans Cell
- Granulomatosis, Langerhans Cell
- Langerhans Cell Granulomatoses
- Hand-Schueller-Christian Disease
- Disease, Hand-Schueller-Christian
- Hand Schueller Christian Disease
Pulmonary Histiocytosis X- Pulmonary Histiocytosis X
- Histiocytosis X, Pulmonary
- Pulmonary Langerhans Cell Granulomatosis
- Langerhans Cell Granulomatosis, Pulmonary
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Below are MeSH descriptors whose meaning is more general than "Histiocytosis, Langerhans-Cell".
Below are MeSH descriptors whose meaning is more specific than "Histiocytosis, Langerhans-Cell".
This graph shows the total number of publications written about "Histiocytosis, Langerhans-Cell" by people in this website by year, and whether "Histiocytosis, Langerhans-Cell" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 |
2001 | 1 | 0 | 1 |
2003 | 1 | 0 | 1 |
2004 | 1 | 0 | 1 |
2007 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2015 | 1 | 1 | 2 |
2016 | 2 | 0 | 2 |
2017 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Histiocytosis, Langerhans-Cell" by people in Profiles.
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Janz TA, Camilon PR, Cheung AY, Nguyen SA, White DR, Weber PC. A review of pediatric middle ear tumors and analysis of the demographics, management, and survival of pediatric rhabdomyosarcomas of the middle ear. Int J Pediatr Otorhinolaryngol. 2018 Sep; 112:109-112.
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Shanmugam V, Craig JW, Hornick JL, Morgan EA, Pinkus GS, Pozdnyakova O. Cyclin D1 Is Expressed in Neoplastic Cells of Langerhans Cell Histiocytosis but Not Reactive Langerhans Cell Proliferations. Am J Surg Pathol. 2017 Oct; 41(10):1390-1396.
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Kamionek M, Ahmadi Moghaddam P, Sakhdari A, Kovach AE, Welch M, Meng X, Dresser K, Tomaszewicz K, Cosar EF, Mark EJ, Fraire AE, Hutchinson L. Mutually exclusive extracellular signal-regulated kinase pathway mutations are present in different stages of multi-focal pulmonary Langerhans cell histiocytosis supporting clonal nature of the disease. Histopathology. 2016 Sep; 69(3):499-509.
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Xu J, Sun HH, Fletcher CD, Hornick JL, Morgan EA, Freeman GJ, Hodi FS, Pinkus GS, Rodig SJ. Expression of Programmed Cell Death 1 Ligands (PD-L1 and PD-L2) in Histiocytic and Dendritic Cell Disorders. Am J Surg Pathol. 2016 Apr; 40(4):443-53.
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Nielsen N, Akalin A, Sirkis HM, Most MJ. Multifocal Langerhans Cell Histiocytosis in an Adult. Am J Orthop (Belle Mead NJ). 2015 Dec; 44(12):563-8.
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Gkrouzman E, Cuadra RH, Jacob J. Langerhans Cell Histiocytosis of the Bone Presenting as Back Pain: An Unusual Diagnosis for a Common Complaint. Conn Med. 2015 Aug; 79(7):409-14.
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Goldberg SA, O'Connor SC, Sprinz PG. Prostaglandin inhibitors in the treatment of single-system Langerhans cell histiocytosis: pharmacologic rationale and report of two cases. J Pediatr Hematol Oncol. 2008 Oct; 30(10):778-80.
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Fraire A. Histopathology of pneumothorax: potential diagnostic pitfalls. Arch Pathol Lab Med. 2007 Jun; 131(6):848-9.
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Powell JL, Otis CN. Commenting on "Vulvar langerhans cell histocytosis: a case report and review of the literature" by Santillan et al. 91:241-246. Gynecol Oncol. 2004 Jun; 93(3):719; author reply 719.
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Usmani GN, Westra SJ, Younes S. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 13-2003. A 14-month-old boy with hepatomegaly, perianal lesions, and a bony lump on the forehead. N Engl J Med. 2003 Apr 24; 348(17):1692-701.