Histiocytosis, Langerhans-Cell
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"Histiocytosis, Langerhans-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.
    
			
			
				
				
					
						| Descriptor ID | D006646 | 
					
						| MeSH Number(s) | C08.381.483.375 C15.604.250.400 | 
					
						| Concept/Terms | Histiocytosis, Langerhans-CellHistiocytosis, Langerhans-CellHistiocytosis, Langerhans CellHand-Schueller-Christian SyndromeHand Schueller Christian SyndromeSyndrome, Hand-Schueller-ChristianHand-Schüller-Christian DiseaseDisease, Hand-Schüller-ChristianHand Schüller Christian DiseaseHand-Schüller-Christian SyndromeHand Schüller Christian SyndromeSyndrome, Hand-Schüller-ChristianHistiocytosis XHistiocytosis, GeneralizedGeneralized HistiocytosesGeneralized HistiocytosisHistiocytoses, GeneralizedHistiocytosis-XLangerhans Cell HistiocytosisCell Histiocytoses, LangerhansCell Histiocytosis, LangerhansHistiocytoses, Langerhans CellLangerhans Cell HistiocytosesLangerhans-Cell GranulomatosisGranulomatosis, Langerhans-CellLangerhans-Cell HistiocytosisLetterer-Siwe DiseaseDisease, Letterer-SiweLetterer Siwe DiseaseNon-Lipid ReticuloendotheliosisNon Lipid ReticuloendotheliosisNon-Lipid ReticuloendotheliosesReticuloendothelioses, Non-LipidReticuloendotheliosis, Non-LipidSchueller-Christian DiseaseDisease, Schueller-ChristianSchueller Christian DiseaseSystemic Aleukemic ReticuloendotheliosisAleukemic Reticuloendothelioses, SystemicAleukemic Reticuloendotheliosis, SystemicReticuloendothelioses, Systemic AleukemicReticuloendotheliosis, Systemic AleukemicSystemic Aleukemic ReticuloendotheliosesType 2 HistiocytosisHistiocytoses, Type 2Histiocytosis, Type 2Type 2 HistiocytosesLangerhans Cell GranulomatosisCell Granulomatoses, LangerhansCell Granulomatosis, LangerhansGranulomatoses, Langerhans CellGranulomatosis, Langerhans CellLangerhans Cell GranulomatosesHand-Schueller-Christian DiseaseDisease, Hand-Schueller-ChristianHand Schueller Christian Disease
 Pulmonary Histiocytosis XPulmonary Histiocytosis XHistiocytosis X, PulmonaryPulmonary Langerhans Cell GranulomatosisLangerhans Cell Granulomatosis, Pulmonary
 | 
					
				
			 
			
				Below are MeSH descriptors whose meaning is more general than "Histiocytosis, Langerhans-Cell".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Histiocytosis, Langerhans-Cell".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Histiocytosis, Langerhans-Cell" by people in this website by year, and whether "Histiocytosis, Langerhans-Cell" was a major or minor topic of these publications. 
				
					 
                    To see the data from this visualization as text, 
click here. 
                
		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 2001 | 1 | 0 | 1 | 
| 2004 | 1 | 1 | 2 | 
| 2006 | 0 | 1 | 1 | 
| 2007 | 0 | 1 | 1 | 
| 2008 | 1 | 0 | 1 | 
| 2015 | 1 | 1 | 2 | 
| 2016 | 1 | 0 | 1 | 
| 2022 | 1 | 0 | 1 | 
                    To return to the timeline, 
click here.
                 
			 	
			
			
			
			
				Below are the most recent publications written about "Histiocytosis, Langerhans-Cell" by people in Profiles.
						
					
								- 
								Hochhegger B, Patel PP, Zanon M, M?ller E, Ferreira Correa L, Verma N, Mohammed TL, Quinto Dos Reis Hochhegger D, Irion K, Marchiori E. Narrowing the Differential Diagnosis of Cystic Lesions in Smokers with Expiratory CT Acquisition Using the Cyst-Airway Communication Hypothesis. Lung. 2022 12; 200(6):817-820. 
- 
								Janz TA, Camilon PR, Cheung AY, Nguyen SA, White DR, Weber PC. A review of pediatric middle ear tumors and analysis of the demographics, management, and survival of pediatric rhabdomyosarcomas of the middle ear. Int J Pediatr Otorhinolaryngol. 2018 Sep; 112:109-112. 
- 
								Shanmugam V, Craig JW, Hornick JL, Morgan EA, Pinkus GS, Pozdnyakova O. Cyclin D1 Is Expressed in Neoplastic Cells of Langerhans Cell Histiocytosis but Not Reactive Langerhans Cell Proliferations. Am J Surg Pathol. 2017 Oct; 41(10):1390-1396. 
- 
								Kamionek M, Ahmadi Moghaddam P, Sakhdari A, Kovach AE, Welch M, Meng X, Dresser K, Tomaszewicz K, Cosar EF, Mark EJ, Fraire AE, Hutchinson L. Mutually exclusive extracellular signal-regulated kinase pathway mutations are present in different stages of multi-focal pulmonary Langerhans cell histiocytosis supporting clonal nature of the disease. Histopathology. 2016 Sep; 69(3):499-509. 
- 
								Xu J, Sun HH, Fletcher CD, Hornick JL, Morgan EA, Freeman GJ, Hodi FS, Pinkus GS, Rodig SJ. Expression of Programmed Cell Death 1 Ligands (PD-L1 and PD-L2) in Histiocytic and Dendritic Cell Disorders. Am J Surg Pathol. 2016 Apr; 40(4):443-53. 
- 
								Nielsen N, Akalin A, Sirkis HM, Most MJ. Multifocal Langerhans Cell Histiocytosis in an Adult. Am J Orthop (Belle Mead NJ). 2015 Dec; 44(12):563-8. 
- 
								Gkrouzman E, Cuadra RH, Jacob J. Langerhans Cell Histiocytosis of the Bone Presenting as Back Pain: An Unusual Diagnosis for a Common Complaint. Conn Med. 2015 Aug; 79(7):409-14. 
- 
								Goldberg SA, O'Connor SC, Sprinz PG. Prostaglandin inhibitors in the treatment of single-system Langerhans cell histiocytosis: pharmacologic rationale and report of two cases. J Pediatr Hematol Oncol. 2008 Oct; 30(10):778-80. 
- 
								Fraire A. Histopathology of pneumothorax: potential diagnostic pitfalls. Arch Pathol Lab Med. 2007 Jun; 131(6):848-9. 
- 
								Orens JB, Estenne M, Arcasoy S, Conte JV, Corris P, Egan JJ, Egan T, Keshavjee S, Knoop C, Kotloff R, Martinez FJ, Nathan S, Palmer S, Patterson A, Singer L, Snell G, Studer S, Vachiery JL, Glanville AR. International guidelines for the selection of lung transplant candidates: 2006 update--a consensus report from the Pulmonary Scientific Council of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 2006 Jul; 25(7):745-55.