Receptors, CCR2

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"Receptors, CCR2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

CCR receptors with specificity for CHEMOKINE CCL2 and several other CCL2-related chemokines. They are expressed at high levels in T-LYMPHOCYTES; B-LYMPHOCYTES; MACROPHAGES; BASOPHILS; and NK CELLS.

Descriptor ID	D054390
MeSH Number(s)	D12.776.543.750.695.160.150.200 D12.776.543.750.705.852.125.150.200
Concept/Terms	Receptors, CCR2 Receptors, CCR2 MCP-1 Receptor MCP 1 Receptor Receptor, MCP-1 MCP-1 Receptors MCP 1 Receptors Receptors, MCP-1 Monocyte Chemoattractant Protein 1 Receptor CCR2 Receptor Receptor, CCR2 CCR2 Receptors CC Chemokine Receptor 2 CD192 Antigens Antigens, CD192 CC Chemokine Receptor-2 Chemokine Receptor-2, CC Receptor-2, CC Chemokine CC Chemokine Receptors 2 CCR2a Receptor CCR2a Receptor Receptor, CCR2a MCP-1RA CCR-2A MCP-1 Receptor CCR 2A MCP 1 Receptor MCP-1 Receptor, CCR-2A Receptor, CCR-2A MCP-1 MCP-1 Receptor CCR-2A MCP 1 Receptor CCR 2A Receptor CCR-2A, MCP-1 CCR2b Receptor CCR2b Receptor Receptor, CCR2b MCP-1 Receptor 2B MCP 1 Receptor 2B CCR2b Receptors Receptors, CCR2b CC CKR2B MCP-1RB

Below are MeSH descriptors whose meaning is more general than "Receptors, CCR2".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, G-Protein-Coupled [D12.776.543.750.695]
Receptors, Chemokine [D12.776.543.750.695.160]
Receptors, CCR [D12.776.543.750.695.160.150]
Receptors, CCR2 [D12.776.543.750.695.160.150.200]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Chemokine [D12.776.543.750.705.852.125]
Receptors, CCR [D12.776.543.750.705.852.125.150]
Receptors, CCR2 [D12.776.543.750.705.852.125.150.200]

Below are MeSH descriptors whose meaning is related to "Receptors, CCR2".

Below are MeSH descriptors whose meaning is more specific than "Receptors, CCR2".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, CCR2" by people in this website by year, and whether "Receptors, CCR2" was a major or minor topic of these publications.

Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 2010 and 2011 and 2018 and 2019 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2010	0	1	1
2011	1	0	1
2018	0	1	1
2019	1	0	1
2020	1	0	1

Below are the most recent publications written about "Receptors, CCR2" by people in Profiles.

Lowe PP, Morel C, Ambade A, Iracheta-Vellve A, Kwiatkowski E, Satishchandran A, Furi I, Cho Y, Gyongyosi B, Catalano D, Lefebvre E, Fischer L, Seyedkazemi S, Schafer DP, Szabo G. Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations. J Neuroinflammation. 2020 Oct 09; 17(1):296.

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Ambade A, Lowe P, Kodys K, Catalano D, Gyongyosi B, Cho Y, Iracheta-Vellve A, Adejumo A, Saha B, Calenda C, Mehta J, Lefebvre E, Vig P, Szabo G. Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol-Induced Liver Damage, Steatosis, and Inflammation in Mice. Hepatology. 2019 03; 69(3):1105-1121.

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Bodogai M, O'Connell J, Kim K, Kim Y, Moritoh K, Chen C, Gusev F, Vaughan K, Shulzhenko N, Mattison JA, Lee-Chang C, Chen W, Carlson O, Becker KG, Gurung M, Morgun A, White J, Meade T, Perdue K, Mack M, Ferrucci L, Trinchieri G, de Cabo R, Rogaev E, Egan J, Wu J, Biragyn A. Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells. Sci Transl Med. 2018 11 14; 10(467).

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Egan CE, Daugherity EK, Rogers AB, Abi Abdallah DS, Denkers EY, Maurer KJ. CCR2 and CD44 promote inflammatory cell recruitment during fatty liver formation in a lithogenic diet fed mouse model. PLoS One. 2013; 8(6):e65247.

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Mandrekar P, Ambade A, Lim A, Szabo G, Catalano D. An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice. Hepatology. 2011 Dec; 54(6):2185-97.

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Dai E, Liu LY, Wang H, McIvor D, Sun YM, Macaulay C, King E, Munuswamy-Ramanujam G, Bartee MY, Williams J, Davids J, Charo I, McFadden G, Esko JD, Lucas AR. Inhibition of chemokine-glycosaminoglycan interactions in donor tissue reduces mouse allograft vasculopathy and transplant rejection. PLoS One. 2010 May 06; 5(5):e10510.

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Alexander L, Weiskopf E, Greenough TC, Gaddis NC, Auerbach MR, Malim MH, O'Brien SJ, Walker BD, Sullivan JL, Desrosiers RC. Unusual polymorphisms in human immunodeficiency virus type 1 associated with nonprogressive infection. J Virol. 2000 May; 74(9):4361-76.

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Weber C, Draude G, Weber KS, W?bert J, Lorenz RL, Weber PC. Downregulation by tumor necrosis factor-alpha of monocyte CCR2 expression and monocyte chemotactic protein-1-induced transendothelial migration is antagonized by oxidized low-density lipoprotein: a potential mechanism of monocyte retention in atherosclerotic lesions. Atherosclerosis. 1999 Jul; 145(1):115-23.

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Weber KS, von Hundelshausen P, Clark-Lewis I, Weber PC, Weber C. Differential immobilization and hierarchical involvement of chemokines in monocyte arrest and transmigration on inflamed endothelium in shear flow. Eur J Immunol. 1999 02; 29(2):700-12.

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