Cyclic AMP

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"Cyclic AMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.

Descriptor ID	D000242
MeSH Number(s)	D03.633.100.759.646.138.395 D13.695.462.200 D13.695.667.138.395 D13.695.827.068.395
Concept/Terms	Cyclic AMP Cyclic AMP AMP, Cyclic Adenosine Cyclic-3',5'-Monophosphate Cyclic-3',5'-Monophosphate, Adenosine Adenosine Cyclic Monophosphate Cyclic Monophosphate, Adenosine Monophosphate, Adenosine Cyclic Adenosine Cyclic 3,5 Monophosphate Adenosine Cyclic 3',5'-Monophosphate 3',5'-Monophosphate, Adenosine Cyclic Adenosine Cyclic 3',5' Monophosphate Cyclic 3',5'-Monophosphate, Adenosine Cyclic AMP, Monosodium Salt Cyclic AMP, Monosodium Salt Cyclic AMP, Sodium Salt Cyclic AMP, Sodium Salt Cyclic AMP, Monoammonium Salt Cyclic AMP, Monoammonium Salt Cyclic AMP, (R)-Isomer Cyclic AMP, (R)-Isomer Cyclic AMP, Disodium Salt Cyclic AMP, Disodium Salt Cyclic AMP, Monopotassium Salt Cyclic AMP, Monopotassium Salt

Below are MeSH descriptors whose meaning is more general than "Cyclic AMP".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Purines [D03.633.100.759]
Purine Nucleotides [D03.633.100.759.646]
Adenine Nucleotides [D03.633.100.759.646.138]
Cyclic AMP [D03.633.100.759.646.138.395]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleotides [D13.695]
Nucleotides, Cyclic [D13.695.462]
Cyclic AMP [D13.695.462.200]
Purine Nucleotides [D13.695.667]
Adenine Nucleotides [D13.695.667.138]
Cyclic AMP [D13.695.667.138.395]
Ribonucleotides [D13.695.827]
Adenine Nucleotides [D13.695.827.068]
Cyclic AMP [D13.695.827.068.395]

Below are MeSH descriptors whose meaning is related to "Cyclic AMP".

Below are MeSH descriptors whose meaning is more specific than "Cyclic AMP".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cyclic AMP" by people in this website by year, and whether "Cyclic AMP" was a major or minor topic of these publications.

Bar chart showing 93 publications over 29 distinct years, with a maximum of 9 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	4	1	5
1996	1	2	3
1997	1	2	3
1998	2	1	3
1999	1	4	5
2000	2	1	3
2001	1	1	2
2002	0	9	9
2003	2	2	4
2004	3	0	3
2005	1	1	2
2006	0	4	4
2007	0	3	3
2008	0	3	3
2009	1	2	3
2010	1	4	5
2011	0	1	1
2012	1	1	2
2013	1	4	5
2014	2	2	4
2015	1	3	4
2016	0	2	2
2017	1	1	2
2019	1	1	2
2020	0	1	1
2021	3	1	4
2022	0	1	1
2024	3	1	4
2025	1	0	1

Below are the most recent publications written about "Cyclic AMP" by people in Profiles.

Luque GM, Jablo?ski M, Schiavi-Ehrenhaus LJ, Del Prado RC, Balbach M, Romarowski A, Martin-Hidalgo D, Visconti PE, Krapf D, Darszon A, Krapf D, Buck J, Levin LR, Buffone MG. Bovine serum albumin-induced calcium influx triggers soluble adenylyl cyclase activation and cyclic AMP signalling pathways in mouse sperm capacitation. J Physiol. 2025 May; 603(9):2633-2653.

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Desai A, Loureiro ZY, DeSouza T, Yang Q, Solivan-Rivera J, Corvera S. cAMP driven UCP1 induction in human adipocytes requires ATGL-catalyzed lipolysis. Mol Metab. 2024 Dec; 90:102051.

View in: PubMed
Visconti PE, Levin LR, Buck J. David Garbers and the Birth of cAMP Biology in Mammalian Sperm. Mol Reprod Dev. 2024 10; 91(10):e23773.

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Jablo?ski M, La Spina FA, Schiavi-Ehrenhaus LJ, Mar?n-Briggiler CI, Gomez-Elias MD, Krapf D, Visconti PE, Krapf D, Luque GM, Buffone MG. Dual role of valosin-containing protein (VCP/p97) in mouse sperm during capacitation. Reproduction. 2024 08 01; 168(2).

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Mohanty G, Sanchez-Cardenas C, Paudel B, Tourzani DA, Salicioni AM, Santi CM, Gervasi MG, Pilsner JR, Darszon A, Visconti PE. Differential role of bovine serum albumin and HCO3- in the regulation of GSK3 alpha during mouse sperm capacitation. Mol Hum Reprod. 2024 Feb 29; 30(3).

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Guilherme A, Rowland LA, Wang H, Czech MP. The adipocyte supersystem of insulin and cAMP signaling. Trends Cell Biol. 2023 04; 33(4):340-354.

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Tourzani DA, Battistone MA, Salicioni AM, Breton S, Visconti PE, Gervasi MG. Caput Ligation Renders Immature Mouse Sperm Motile and Capable to Undergo cAMP-Dependent Phosphorylation. Int J Mol Sci. 2021 Sep 23; 22(19).

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Luque GM, Xu X, Romarowski A, Gervasi MG, Orta G, De la Vega-Beltr?n JL, Stival C, Gilio N, Dalotto-Moreno T, Krapf D, Visconti PE, Krapf D, Darszon A, Buffone MG. Cdc42 localized in the CatSper signaling complex regulates cAMP-dependent pathways in mouse sperm. FASEB J. 2021 08; 35(8):e21723.

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Takei GL, Tourzani DA, Paudel B, Visconti PE. Activation of cAMP-dependent phosphorylation pathways is independent of ROS production during mouse sperm capacitation. Mol Reprod Dev. 2021 08; 88(8):544-557.

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Roderick JE, Gallagher KM, Murphy LC, O'Connor KW, Tang K, Zhang B, Brehm MA, Greiner DL, Yu J, Zhu LJ, Green MR, Kelliher MA. Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death. Blood. 2021 01 28; 137(4):500-512.

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