Cyclic AMP

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"Cyclic AMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.

Descriptor ID	D000242
MeSH Number(s)	D03.633.100.759.646.138.395 D13.695.462.200 D13.695.667.138.395 D13.695.827.068.395
Concept/Terms	Cyclic AMP Cyclic AMP AMP, Cyclic Adenosine Cyclic-3',5'-Monophosphate Cyclic-3',5'-Monophosphate, Adenosine Adenosine Cyclic Monophosphate Cyclic Monophosphate, Adenosine Monophosphate, Adenosine Cyclic Adenosine Cyclic 3,5 Monophosphate Adenosine Cyclic 3',5'-Monophosphate 3',5'-Monophosphate, Adenosine Cyclic Adenosine Cyclic 3',5' Monophosphate Cyclic 3',5'-Monophosphate, Adenosine Cyclic AMP, Monosodium Salt Cyclic AMP, Monosodium Salt Cyclic AMP, Sodium Salt Cyclic AMP, Sodium Salt Cyclic AMP, Monoammonium Salt Cyclic AMP, Monoammonium Salt Cyclic AMP, (R)-Isomer Cyclic AMP, (R)-Isomer Cyclic AMP, Disodium Salt Cyclic AMP, Disodium Salt Cyclic AMP, Monopotassium Salt Cyclic AMP, Monopotassium Salt

Below are MeSH descriptors whose meaning is more general than "Cyclic AMP".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Purines [D03.633.100.759]
Purine Nucleotides [D03.633.100.759.646]
Adenine Nucleotides [D03.633.100.759.646.138]
Cyclic AMP [D03.633.100.759.646.138.395]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleotides [D13.695]
Nucleotides, Cyclic [D13.695.462]
Cyclic AMP [D13.695.462.200]
Purine Nucleotides [D13.695.667]
Adenine Nucleotides [D13.695.667.138]
Cyclic AMP [D13.695.667.138.395]
Ribonucleotides [D13.695.827]
Adenine Nucleotides [D13.695.827.068]
Cyclic AMP [D13.695.827.068.395]

Below are MeSH descriptors whose meaning is related to "Cyclic AMP".

Below are MeSH descriptors whose meaning is more specific than "Cyclic AMP".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cyclic AMP" by people in this website by year, and whether "Cyclic AMP" was a major or minor topic of these publications.

Bar chart showing 88 publications over 28 distinct years, with a maximum of 8 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	0	3	3
1994	3	4	7
1995	3	1	4
1996	1	2	3
1997	1	2	3
1998	2	1	3
1999	1	4	5
2000	2	1	3
2001	1	2	3
2002	0	8	8
2003	1	1	2
2004	2	0	2
2005	1	2	3
2006	0	3	3
2007	0	2	2
2008	0	2	2
2009	0	1	1
2010	1	4	5
2011	0	2	2
2012	1	1	2
2013	1	3	4
2014	2	1	3
2015	1	3	4
2016	0	2	2
2017	1	1	2
2019	1	1	2
2020	0	1	1
2021	3	1	4

Below are the most recent publications written about "Cyclic AMP" by people in Profiles.

Tourzani DA, Battistone MA, Salicioni AM, Breton S, Visconti PE, Gervasi MG. Caput Ligation Renders Immature Mouse Sperm Motile and Capable to Undergo cAMP-Dependent Phosphorylation. Int J Mol Sci. 2021 Sep 23; 22(19).

View in: PubMed
Luque GM, Xu X, Romarowski A, Gervasi MG, Orta G, De la Vega-Beltrán JL, Stival C, Gilio N, Dalotto-Moreno T, Krapf D, Visconti PE, Krapf D, Darszon A, Buffone MG. Cdc42 localized in the CatSper signaling complex regulates cAMP-dependent pathways in mouse sperm. FASEB J. 2021 08; 35(8):e21723.

View in: PubMed
Takei GL, Tourzani DA, Paudel B, Visconti PE. Activation of cAMP-dependent phosphorylation pathways is independent of ROS production during mouse sperm capacitation. Mol Reprod Dev. 2021 08; 88(8):544-557.

View in: PubMed
Roderick JE, Gallagher KM, Murphy LC, O'Connor KW, Tang K, Zhang B, Brehm MA, Greiner DL, Yu J, Zhu LJ, Green MR, Kelliher MA. Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death. Blood. 2021 01 28; 137(4):500-512.

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Henriques F, Bedard AH, Guilherme A, Kelly M, Chi J, Zhang P, Lifshitz LM, Bellvé K, Rowland LA, Yenilmez B, Kumar S, Wang Y, Luban J, Weinstein LS, Lin JD, Cohen P, Czech MP. Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis. Cell Rep. 2020 08 04; 32(5):107998.

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Maybruck BT, Lam WC, Specht CA, Ilagan MXG, Donlin MJ, Lodge JK. The Aminoalkylindole BML-190 Negatively Regulates Chitosan Synthesis via the Cyclic AMP/Protein Kinase A1 Pathway in Cryptococcus neoformans. mBio. 2019 12 17; 10(6).

View in: PubMed
Domínguez-Ordóñez R, García-Juárez M, Lima-Hernández FJ, Gómora-Arrati P, Domínguez-Salazar E, Luna-Hernández A, Hoffman KL, Blaustein JD, Etgen AM, González-Flores O. Protein kinase inhibitors infused intraventricularly or into the ventromedial hypothalamus block short latency facilitation of lordosis by oestradiol. J Neuroendocrinol. 2019 12; 31(12):e12809.

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Neto A, Ceol CJ. Melanoma-associated GRM3 variants dysregulate melanosome trafficking and cAMP signaling. Pigment Cell Melanoma Res. 2018 01; 31(1):115-119.

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Guilherme A, Pedersen DJ, Henchey E, Henriques FS, Danai LV, Shen Y, Yenilmez B, Jung D, Kim JK, Lodhi IJ, Semenkovich CF, Czech MP. Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming. Mol Metab. 2017 08; 6(8):781-796.

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Puga Molina LC, Pinto NA, Torres Rodríguez P, Romarowski A, Vicens Sanchez A, Visconti PE, Darszon A, Treviño CL, Buffone MG. Essential Role of CFTR in PKA-Dependent Phosphorylation, Alkalinization, and Hyperpolarization During Human Sperm Capacitation. J Cell Physiol. 2017 Jun; 232(6):1404-1414.

View in: PubMed

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