Genes, Homeobox

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"Genes, Homeobox" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS.

Descriptor ID	D005801
MeSH Number(s)	G05.360.340.024.340.230.500
Concept/Terms	Genes, Homeobox Genes, Homeobox Gene, Homeobox Homeobox Gene Homeobox Genes Genes, Homeotic Gene, Homeotic Homeotic Gene Hox Genes Gene, Hox Genes, Hox Hox Gene Genes, Homeo Box Gene, Homeo Box Homeo Box Gene Homeo Box Genes Homeotic Genes Homeo Box Sequence Homeo Box Sequence Homeo Box Sequences Sequences, Homeo Box Homeo Boxes Sequence, Homeo Box Homeobox Sequence Homeobox Sequences Sequence, Homeobox Sequences, Homeobox Homeoboxes Homeo Box Homeobox

Below are MeSH descriptors whose meaning is more general than "Genes, Homeobox".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Genes [G05.360.340.024.340]
Genes, Developmental [G05.360.340.024.340.230]
Genes, Homeobox [G05.360.340.024.340.230.500]

Below are MeSH descriptors whose meaning is related to "Genes, Homeobox".

Below are MeSH descriptors whose meaning is more specific than "Genes, Homeobox".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Genes, Homeobox" by people in this website by year, and whether "Genes, Homeobox" was a major or minor topic of these publications.

Bar chart showing 9 publications over 7 distinct years, with a maximum of 2 publications in 1995 and 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	1	2
1999	1	0	1
2000	1	0	1
2002	1	1	2
2011	0	1	1
2014	0	1	1
2016	0	1	1

Below are the most recent publications written about "Genes, Homeobox" by people in Profiles.

Rodr?guez-Carballo E, Lopez-Delisle L, Zhan Y, Fabre PJ, Beccari L, El-Idrissi I, Huynh THN, Ozadam H, Dekker J, Duboule D. The HoxD cluster is a dynamic and resilient TAD boundary controlling the segregation of antagonistic regulatory landscapes. Genes Dev. 2017 11 15; 31(22):2264-2281.

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Pan Y, Comiskey DF, Kelly LE, Chandler DS, El-Hodiri HM. Regulation of photoreceptor gene transcription via a highly conserved transcriptional regulatory element by vsx gene products. Mol Vis. 2016; 22:1421-1428.

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Labadorf A, Hoss AG, Lagomarsino V, Latourelle JC, Hadzi TC, Bregu J, MacDonald ME, Gusella JF, Chen JF, Akbarian S, Weng Z, Myers RH. RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression. PLoS One. 2015; 10(12):e0143563.

View in: PubMed
Moroz LL, Kocot KM, Citarella MR, Dosung S, Norekian TP, Povolotskaya IS, Grigorenko AP, Dailey C, Berezikov E, Buckley KM, Ptitsyn A, Reshetov D, Mukherjee K, Moroz TP, Bobkova Y, Yu F, Kapitonov VV, Jurka J, Bobkov YV, Swore JJ, Girardo DO, Fodor A, Gusev F, Sanford R, Bruders R, Kittler E, Mills CE, Rast JP, Derelle R, Solovyev VV, Kondrashov FA, Swalla BJ, Sweedler JV, Rogaev EI, Halanych KM, Kohn AB. The ctenophore genome and the evolutionary origins of neural systems. Nature. 2014 Jun 05; 510(7503):109-14.

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Hoss AG, Kartha VK, Dong X, Latourelle JC, Dumitriu A, Hadzi TC, Macdonald ME, Gusella JF, Akbarian S, Chen JF, Weng Z, Myers RH. MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis. PLoS Genet. 2014 Feb; 10(2):e1004188.

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Ladam F, Sagerstr?m CG. Hox regulation of transcription: more complex(es). Dev Dyn. 2014 Jan; 243(1):4-15.

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Anderson AE, Karandikar UC, Pepple KL, Chen Z, Bergmann A, Mardon G. The enhancer of trithorax and polycomb gene Caf1/p55 is essential for cell survival and patterning in Drosophila development. Development. 2011 May; 138(10):1957-66.

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Choe SK, Sagerstr?m CG. Paralog group 1 hox genes regulate rhombomere 5/6 expression of vhnf1, a repressor of rostral hindbrain fates, in a meis-dependent manner. Dev Biol. 2004 Jul 15; 271(2):350-61.

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Sagerstr?m CG. PbX marks the spot. Dev Cell. 2004 Jun; 6(6):737-8.

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Becker T, Ostendorff HP, Bossenz M, Schl?ter A, Becker CG, Peirano RI, Bach I. Multiple functions of LIM domain-binding CLIM/NLI/Ldb cofactors during zebrafish development. Mech Dev. 2002 Sep; 117(1-2):75-85.

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