 Cyclooxygenase 1
"Cyclooxygenase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A constitutively-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes.
| Descriptor ID |
D051545
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| MeSH Number(s) |
D08.811.600.720.500
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| Concept/Terms |
Cyclooxygenase 1- Cyclooxygenase 1
- Cyclo-Oxygenase I
- Cyclo Oxygenase I
- Prostaglandin H Synthase-1
- Prostaglandin H Synthase 1
- COX-1 Prostaglandin Synthase
- COX 1 Prostaglandin Synthase
- Prostaglandin Synthase, COX-1
- Synthase, COX-1 Prostaglandin
- Cyclooxygenase-1
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Below are MeSH descriptors whose meaning is more general than "Cyclooxygenase 1".
Below are MeSH descriptors whose meaning is more specific than "Cyclooxygenase 1".
This graph shows the total number of publications written about "Cyclooxygenase 1" by people in this website by year, and whether "Cyclooxygenase 1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 0 | 3 | 3 | | 2009 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclooxygenase 1" by people in Profiles.
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Shay AE, Diwakar BT, Guan BJ, Narayan V, Urban JF, Prabhu KS. IL-4 up-regulates cyclooxygenase-1 expression in macrophages. J Biol Chem. 2017 09 01; 292(35):14544-14555.
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DeFilippis AP, Oloyede OS, Andrikopoulou E, Saenger AK, Palachuvattil JM, Fasoro YA, Guallar E, Blumenthal RS, Kickler TS, Jaffe AS, Gerstenblith G, Schulman SP, Rade JJ. Thromboxane A(2) generation, in the absence of platelet COX-1 activity, in patients with and without atherothrombotic myocardial infarction. Circ J. 2013; 77(11):2786-92.
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O'Connor M, Kellett A, McCann M, Rosair G, McNamara M, Howe O, Creaven BS, McClean S, Kia AF, O'Shea D, Devereux M. Copper(II) complexes of salicylic acid combining superoxide dismutase mimetic properties with DNA binding and cleaving capabilities display promising chemotherapeutic potential with fast acting in vitro cytotoxicity against cisplatin sensitive and resistant cancer cell lines. J Med Chem. 2012 Mar 8; 55(5):1957-68.
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Frelinger AL, Li Y, Linden MD, Barnard MR, Fox ML, Christie DJ, Furman MI, Michelson AD. Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization. Circulation. 2009 Dec 22; 120(25):2586-96.
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Lee CW, Rickman B, Rogers AB, Muthupalani S, Takaishi S, Yang P, Wang TC, Fox JG. Combination of sulindac and antimicrobial eradication of Helicobacter pylori prevents progression of gastric cancer in hypergastrinemic INS-GAS mice. Cancer Res. 2009 Oct 15; 69(20):8166-74.
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Loftus JP, Black SJ, Pettigrew A, Abrahamsen EJ, Belknap JK. Early laminar events involving endothelial activation in horses with black walnut- induced laminitis. Am J Vet Res. 2007 Nov; 68(11):1205-11.
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Patel D, Moonis M. Clinical implications of aspirin resistance. Expert Rev Cardiovasc Ther. 2007 Sep; 5(5):969-75.
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Freedman JE. Heritability, platelet function, and aspirin: a link established but cause unknown. Circulation. 2007 May 15; 115(19):2468-70.
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Freedman JE. The aspirin resistance controversy: clinical entity or platelet heterogeneity? Circulation. 2006 Jun 27; 113(25):2865-7.
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Frelinger AL, Furman MI, Linden MD, Li Y, Fox ML, Barnard MR, Michelson AD. Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance. Circulation. 2006 Jun 27; 113(25):2888-96.
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