Thromboxanes

"Thromboxanes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Physiologically active compounds found in many organs of the body. They are formed in vivo from the prostaglandin endoperoxides and cause platelet aggregation, contraction of arteries, and other biological effects. Thromboxanes are important mediators of the actions of polyunsaturated fatty acids transformed by cyclooxygenase.

Descriptor ID	D013931
MeSH Number(s)	D10.251.355.255.100.825 D10.251.355.310.166.971
Concept/Terms	Thromboxanes Thromboxanes

Below are MeSH descriptors whose meaning is more general than "Thromboxanes".

Chemicals and Drugs [D]
Lipids [D10]
Fatty Acids [D10.251]
Fatty Acids, Unsaturated [D10.251.355]
Eicosanoids [D10.251.355.255]
Arachidonic Acids [D10.251.355.255.100]
Thromboxanes [D10.251.355.255.100.825]
Fatty Acids, Essential [D10.251.355.310]
Arachidonic Acids [D10.251.355.310.166]
Thromboxanes [D10.251.355.310.166.971]

Below are MeSH descriptors whose meaning is related to "Thromboxanes".

Below are MeSH descriptors whose meaning is more specific than "Thromboxanes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Thromboxanes" by people in this website by year, and whether "Thromboxanes" was a major or minor topic of these publications.

Bar chart showing 6 publications over 5 distinct years, with a maximum of 2 publications in 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2011	1	0	1
2013	0	1	1
2022	0	2	2
2024	1	0	1
2026	1	0	1

Below are the most recent publications written about "Thromboxanes" by people in Profiles.

Abdelmoez AM, Jollet M, Yu X, Rizo-Roca D, Marica AA, Ortiz de Zevallos J, Dollet L, Borg ML, Bj?rnholm M, Checa A, Olsson T, Otten J, Zierath JR, Krook A, Schwartz TW, Chibalin AV, Pillon NJ. Thromboxane signalling links immune activation to enhanced glucose uptake in skeletal muscle. Diabetologia. 2026 Jun; 69(6):1643-1658.

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Barton BA, Kronsberg SS, Hariri E, Vasan RS, Rade GA, Xanthakis V, Kickler TS, Rade JJ. Adjustment for Renal Function Improves the Prognostic Performance of Urinary Thromboxane Metabolites. Clin Chem. 2024 04 03; 70(4):660-668.

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Hariri E, Kakouros N, Bunsick DA, Russell SD, Mudd JO, Laws K, Lake MW, Rade JJ. Nonplatelet thromboxane generation is associated with impaired cardiovascular performance and mortality in heart failure. Am J Physiol Heart Circ Physiol. 2022 07 01; 323(1):H248-H255.

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Rade JJ, Barton BA, Vasan RS, Kronsberg SS, Xanthakis V, Keaney JF, Hamburg NM, Kakouros N, Kickler TA. Association of Thromboxane Generation?With Survival in Aspirin?Users?and Nonusers. J Am Coll Cardiol. 2022 07 19; 80(3):233-250.

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Gleim S, Stitham J, Tang WH, Li H, Douville K, Chelikani P, Rade JJ, Martin KA, Hwa J. Human thromboxane A2 receptor genetic variants: in silico, in vitro and "in platelet" analysis. PLoS One. 2013; 8(6):e67314.

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Tang WH, Stitham J, Gleim S, Di Febbo C, Porreca E, Fava C, Tacconelli S, Capone M, Evangelista V, Levantesi G, Wen L, Martin K, Minuz P, Rade J, Patrignani P, Hwa J. Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane. J Clin Invest. 2011 Nov; 121(11):4462-76.

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Freedman JE. Heritability, platelet function, and aspirin: a link established but cause unknown. Circulation. 2007 May 15; 115(19):2468-70.

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Hrboticky N, Tang L, Zimmer B, Lux I, Weber PC. Lovastatin increases arachidonic acid levels and stimulates thromboxane synthesis in human liver and monocytic cell lines. J Clin Invest. 1994 Jan; 93(1):195-203.

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Lorenz R, Weber PC. Thromboxane as diagnostic tool and therapeutic target in cardiovascular disease. Eicosanoids. 1992; 5 Suppl:S53-5.

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Uedelhoven WM, Meese CO, Weber PC. Analysis of the major urinary thromboxane metabolites, 2,3-dinorthromboxane B2 and 11-dehydrothromboxane B2, by gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry. J Chromatogr. 1989 Dec 29; 497:1-16.

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