"Leukotrienes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.
| Descriptor ID |
D015289
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| MeSH Number(s) |
D10.251.355.255.100.450 D10.251.355.310.166.887 D23.469.050.175.450
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Leukotrienes".
Below are MeSH descriptors whose meaning is more specific than "Leukotrienes".
This graph shows the total number of publications written about "Leukotrienes" by people in this website by year, and whether "Leukotrienes" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Leukotrienes" by people in Profiles.
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Sun H, Zhang J, Wang J, Sun T, Xiao H, Zhang JS. Association between genetic variants of the leukotriene biosynthesis pathway and the risk of stroke: a case-control study in the Chinese Han population. Chin Med J (Engl). 2013 Jan; 126(2):254-9.
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Wixted JJ, Fanning P, Rothkopf I, Stein G, Lian J. Arachidonic acid, eicosanoids, and fracture repair. J Orthop Trauma. 2010 Sep; 24(9):539-42.
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Soyer OU, Dizdar EA, Keskin O, Lilly C, Kalayci O. Comparison of two methods for exhaled breath condensate collection. Allergy. 2006 Aug; 61(8):1016-8.
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Zhang YY, Walker JL, Huang A, Keaney JF, Clish CB, Serhan CN, Loscalzo J. Expression of 5-lipoxygenase in pulmonary artery endothelial cells. Biochem J. 2002 Jan 15; 361(Pt 2):267-76.
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Fischer AR, Rosenberg MA, Lilly CM, Callery JC, Rubin P, Cohn J, White MV, Igarashi Y, Kaliner MA, Drazen JM, et al. Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma. J Allergy Clin Immunol. 1994 Dec; 94(6 Pt 1):1046-56.
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Drazen JM, Lilly CM, Sperling R, Rubin P, Israel E. Role of cysteinyl leukotrienes in spontaneous asthmatic responses. Adv Prostaglandin Thromboxane Leukot Res. 1994; 22:251-62.
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Carraway RE, Cochrane DE, Salmonsen R. Increased plasma levels of leukotrienes in response to neurotensin. Ann N Y Acad Sci. 1992; 668:317-9.
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Morel DR, Skoskiewicz M, Robinson DR, Bloch KJ, Hoaglin DC, Zapol WM. Leukotrienes, thromboxane A2, and prostaglandins during systemic anaphylaxis in sheep. Am J Physiol. 1991 Sep; 261(3 Pt 2):H782-92.