"Galectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of animal lectins that bind specifically to beta-galactoside in a calcium-independent manner. Members of this class are distiguished from other lectins by the presence of a conserved carbohydrate recognition domain. The majority of proteins in this class bind to sugar molecules in a sulfhydryl-dependent manner and are often referred to as S-type lectins, however this property is not required for membership in this class.
| Descriptor ID |
D037161
|
| MeSH Number(s) |
D12.776.503.307
|
| Concept/Terms |
Galectins- Galectins
- beta-Galactoside Binding Lectin
- Binding Lectin, beta-Galactoside
- Lectin, beta-Galactoside Binding
- beta Galactoside Binding Lectin
- D-Galactoside-Binding Lectin
- D Galactoside Binding Lectin
- Lectin, D-Galactoside-Binding
- S-Type Lectins
- S Type Lectins
- Galaptins
- Galectin
- Lectins, S-Type
- Lectins, S Type
- S-Type Lectin
- Lectin, S-Type
- S Type Lectin
- beta-D-Galactosyl-Specific Lectin
- Lectin, beta-D-Galactosyl-Specific
- beta D Galactosyl Specific Lectin
- Galactose-Binding Lectin
- Galactose Binding Lectin
- Lectin, Galactose-Binding
|
Below are MeSH descriptors whose meaning is more general than "Galectins".
Below are MeSH descriptors whose meaning is more specific than "Galectins".
This graph shows the total number of publications written about "Galectins" by people in this website by year, and whether "Galectins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Galectins" by people in Profiles.
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Rodr?guez-Alc?zar JF, Ataide MA, Engels G, Schmitt-Mabmunyo C, Garbi N, Kastenm?ller W, Latz E, Franklin BS. Charcot-Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1? Inflammation in Human Macrophages. J Immunol. 2019 01 15; 202(2):550-558.
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Conrad ML, Freitag N, Diessler ME, Hernandez R, Barrientos G, Rose M, Casas LA, Barbeito CG, Blois SM. Differential Spatiotemporal Patterns of Galectin Expression are a Hallmark of Endotheliochorial Placentation. Am J Reprod Immunol. 2016 Mar; 75(3):317-25.
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Clayton KL, Haaland MS, Douglas-Vail MB, Mujib S, Chew GM, Ndhlovu LC, Ostrowski MA. T cell Ig and mucin domain-containing protein 3 is recruited to the immune synapse, disrupts stable synapse formation, and associates with receptor phosphatases. J Immunol. 2014 Jan 15; 192(2):782-91.
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Sada-Ovalle I, Ch?vez-Gal?n L, Torre-Bouscoulet L, Nava-Gami?o L, Barrera L, Jayaraman P, Torres-Rojas M, Salazar-Lezama MA, Behar SM. The Tim3-galectin 9 pathway induces antibacterial activity in human macrophages infected with Mycobacterium tuberculosis. J Immunol. 2012 Dec 15; 189(12):5896-902.
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Mujib S, Jones RB, Lo C, Aidarus N, Clayton K, Sakhdari A, Benko E, Kovacs C, Ostrowski MA. Antigen-independent induction of Tim-3 expression on human T cells by the common ?-chain cytokines IL-2, IL-7, IL-15, and IL-21 is associated with proliferation and is dependent on the phosphoinositide 3-kinase pathway. J Immunol. 2012 Apr 15; 188(8):3745-56.
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Sakuishi K, Jayaraman P, Behar SM, Anderson AC, Kuchroo VK. Emerging Tim-3 functions in antimicrobial and tumor immunity. Trends Immunol. 2011 Aug; 32(8):345-9.
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Jayaraman P, Sada-Ovalle I, Beladi S, Anderson AC, Dardalhon V, Hotta C, Kuchroo VK, Behar SM. Tim3 binding to galectin-9 stimulates antimicrobial immunity. J Exp Med. 2010 Oct 25; 207(11):2343-54.
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Hastings WD, Anderson DE, Kassam N, Koguchi K, Greenfield EA, Kent SC, Zheng XX, Strom TB, Hafler DA, Kuchroo VK. TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines. Eur J Immunol. 2009 Sep; 39(9):2492-501.
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Raabe EH, Yoshida K, Schwarting GA. Differential laminin isoform expression in the developing rat olfactory system. Brain Res Dev Brain Res. 1997 Jul 18; 101(1-2):187-96.