 Ali Akalin MD, PhD
| Title | Associate Professor |
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| Institution | University of Massachusetts Medical School |
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| Department | Pathology |
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| Address | University of Massachusetts Medical School
One Innovation Drive, Biotech Three
Worcester MA 01605
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| Phone | 508-793-6152 |
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| vCard | Download vCard |
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| Institution | UMMS - School of Medicine |
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| Department | Pathology |
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| Division | Anatomic Pathology |
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 Biography | Ankara University, Ankara, , Turkey | MD | | | | Virginia Commonwealth University, Richmond, VA, United States | PHD | | Experimental Pathology |
Overview Board Certification | - American Board of Pathology | - Anatomic and Clinical Pathology, 2005
| - Cytopathology, 2007 | | Education | 1992 M.D. | Ankara University, School of Medicine, Ankara, Turkey | 2000 Ph.D. | Virginia Commonwealth University, School of Medicine, Richmond, VA | Residency/Fellowships | | 2001-2005 | Resident in Anatomic and Clinical Pathology, University of Colorado, School of Medicine, Denver, Colorado | 2005-2006 | Fellow in Surgical Pathology, University of Colorado, School of Medicine, Denver, Colorado | 2006-2007 | Fellow in Cytopathology, University of Massachusetts, School of Medicine, Worcester, MA | Academic Appointments | 2007 – present | Assistant Professor, Department of Pathology, University ofMassachusetts, Worcester, MA | Clinical Appointments | | 2007- present | Staff Pathologist, Department of Pathology, University of Massachusetts, Worcester, MA | 2010- present | Director of Head & NeckPathology, Department ofPathology, University of Massachusetts, Worcester, MA | Honors Awards and Grants | | 1999 | Association of Molecular Pathology Trainee Award, Missouri |
Research Interests : Dr. Akalin has broad diagnostic expertise, with interests in head & neck pathology, cytopathology, and pulmonary pathology. He participates in teaching fellows and residents in our department. His research interests include: - Study of new techniques to improve the diagnostic yield in fine needle aspirations. - Specific detection of cervical cancers using cytometry-based molecular diagnostics. - Development of radiolabeled biomarkers for the localization of neoplasms. - Exploration of new diagnostic and prognostic markers in pulmonary disorders with a focus on lung neoplasms. Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Piper AJ, Clark JL, Mercado-Matos J, Matthew-Onabanjo AN, Hsieh CC, Akalin A, Shaw LM. Insulin Receptor Substrate-1 (IRS-1) and IRS-2 expression levels are associated with prognosis in non-small cell lung cancer (NSCLC). PLoS One. 2019; 14(8):e0220567. PMID: 31393907.
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Huang L, Touray S, Akalin A, Ahmad S. A 54-Year-Old Man Presenting With Progressive Dyspnea and Interstitial Lung Abnormalities. Chest. 2019 Mar; 155(3):e69-e74. PMID: 30846077.
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Akalin A, Ergin A, Remiszewski S, Mu X, Raz D, Diem M. Resolving Interobserver Discrepancies in Lung Cancer Diagnoses by Spectral Histopathology. Arch Pathol Lab Med. 2018 Aug 24. PMID: 30141697.
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Specht CA, Lee CK, Huang H, Hester MM, Liu J, Luckie BA, Torres Santana MA, Mirza Z, Khoshkenar P, Abraham A, Shen ZT, Lodge JK, Akalin A, Homan J, Ostroff GR, Levitz SM. Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species. MBio. 2017 Nov 28; 8(6). PMID: 29184017.
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Guerra ES, Lee CK, Specht CA, Yadav B, Huang H, Akalin A, Huh JR, Mueller C, Levitz SM. Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma. PLoS Pathog. 2017 Jan 17; 13(1):e1006175. PMID: 28095479.
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Diem M, Ergin A, Remiszewski S, Mu X, Akalin A, Raz D. Infrared micro-spectroscopy of human tissue: principles and future promises. Faraday Discuss. 2016 Jun 23; 187:9-42. PMID: 27075634.
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Akalin A, Mu X, Kon MA, Ergin A, Remiszewski SH, Thompson CM, Raz DJ, Diem M. Classification of malignant and benign tumors of the lung by infrared spectral histopathology (SHP). Lab Invest. 2015 Jun; 95(6):697. PMID: 26012705.
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Mu X, Kon M, Ergin A, Remiszewski S, Akalin A, Thompson CM, Diem M. Statistical analysis of a lung cancer spectral histopathology (SHP) data set. Analyst. 2015 Apr 7; 140(7):2449-64. PMID: 25664623.
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Akalin A, Mu X, Kon MA, Ergin A, Remiszewski SH, Thompson CM, Raz DJ, Diem M, Bird B, Miljkovic M. Classification of malignant and benign tumors of the lung by infrared spectral histopathology (SHP). Lab Invest. 2015 Apr; 95(4):406-21. PMID: 25664390.
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Walavalkar V, Patwardhan RV, Owens CL, Lithgow M, Wang X, Akalin A, Nompleggi DJ, Zivny J, Wassef W, Marshall C, Levey J, Walter O, Fischer AH. Utility of liquid-based cytologic examination of distal esophageal brushings in the management of Barrett esophagus: a prospective study of 45 cases. J Am Soc Cytopathol. 2015 May - Jun; 4(3):113-121. PMID: 31051691.
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Tsyrkunou AV, Ellison RT, Akalin A, Wiederhold N, Sutton DA, Lindner J, Fan H, Levitz SM, Zivna I. Multifocal Rhizopus microsporus lung infection following brush clearing. Med Mycol Case Rep. 2014 Oct; 6:14-7. PMID: 25379391.
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Parnes AN, Akalin A, Quinlan RM, Vijayaraghavan GR. AIRP best cases in radiologic-pathologic correlation: lactating adenoma. Radiographics. 2013 Mar-Apr; 33(2):455-9. PMID: 23479707.
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Cornejo KM, Shi M, Akalin A, Uy K, Cagle PT, Fraire AE. Pulmonary papillary adenoma: a case report and review of the literature. J Bronchology Interv Pulmonol. 2013 Jan; 20(1):52-7. PMID: 23328145.
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Bird B, Miljkovic MS, Remiszewski S, Akalin A, Kon M, Diem M. Infrared spectral histopathology (SHP): a novel diagnostic tool for the accurate classification of lung cancer. Lab Invest. 2012 Sep; 92(9):1358-73. PMID: 22751349.
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Liu X, Cheng D, Gray BD, Wang Y, Akalin A, Rusckowski M, Pak KY, Hnatowich DJ. Radiolabeled Zn-DPA as a potential infection imaging agent. Nucl Med Biol. 2012 Jul; 39(5):709-14. PMID: 22321532.
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Liu G, Dou S, Akalin A, Rusckowski M, Streeter PR, Shultz LD, Greiner DL. Pretargeting vs. direct targeting of human betalox5 islet cells subcutaneously implanted in mice using an anti-human islet cell antibody. Nucl Med Biol. 2012 Jul; 39(5):645-51. PMID: 22316614.
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Wang JP, Lee CK, Akalin A, Finberg RW, Levitz SM. Contributions of the MyD88-dependent receptors IL-18R, IL-1R, and TLR9 to host defenses following pulmonary challenge with Cryptococcus neoformans. PLoS One. 2011; 6(10):e26232. PMID: 22039448.
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Liu G, Dou S, Baker S, Akalin A, Cheng D, Chen L, Rusckowski M, Hnatowich DJ. A preclinical 188Re tumor therapeutic investigation using MORF/cMORF pretargeting and an antiTAG-72 antibody CC49. Cancer Biol Ther. 2010 Oct 15; 10(8):767-74. PMID: 21099368.
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Liu X, Wang Y, Nakamura K, Kawauchi S, Akalin A, Cheng D, Chen L, Rusckowski M, Hnatowich DJ. Auger radiation-induced, antisense-mediated cytotoxicity of tumor cells using a 3-component streptavidin-delivery nanoparticle with 111In. J Nucl Med. 2009 Apr; 50(4):582-90. PMID: 19289423.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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| Year | Publications |
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| 2009 | 1 | | 2010 | 1 | | 2011 | 1 | | 2012 | 3 | | 2013 | 2 | | 2014 | 2 | | 2015 | 3 | | 2016 | 1 | | 2017 | 2 | | 2018 | 1 | | 2019 | 2 |
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