"Keratin-17" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type I keratin found associated with KERATIN-6 in rapidly proliferating squamous epithelial tissue. Mutations in the gene for keratin-17 have been associated with PACHYONYCHIA CONGENITA, TYPE 2.
| Descriptor ID |
D053537
|
| MeSH Number(s) |
D05.750.078.593.450.300.700 D12.776.220.475.450.300.700 D12.776.860.607.300.700
|
| Concept/Terms |
Keratin-17- Keratin-17
- Keratin 17
- Cytokeratin 17
- Cytokeratin-17
|
Below are MeSH descriptors whose meaning is more general than "Keratin-17".
Below are MeSH descriptors whose meaning is more specific than "Keratin-17".
This graph shows the total number of publications written about "Keratin-17" by people in this website by year, and whether "Keratin-17" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2021 | 1 | 1 | 2 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Keratin-17" by people in Profiles.
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Babu S, Horowitz M, Delgado-Coka LA, Roa-Peña L, Akalin A, Escobar-Hoyos LF, Shroyer KR. Keratin 17 and A2ML1 are negative prognostic biomarkers in non-small cell lung cancer. Pathol Res Pract. 2024 Nov; 263:155643.
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Delgado-Coka LA, Roa-Peña L, Babu S, Horowitz M, Petricoin EF, Matrisian LM, Blais EM, Marchenko N, Allard FD, Akalin A, Jiang W, Larson BK, Hendifar AE, Picozzi VJ, Choi M, Shroyer KR, Escobar-Hoyos LF. Keratin 17 is a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma. Am J Clin Pathol. 2024 09 03; 162(3):314-326.
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Roa-Peña L, Babu S, Leiton CV, Wu M, Taboada S, Akalin A, Buscaglia J, Escobar-Hoyos LF, Shroyer KR. Keratin 17 testing in pancreatic cancer needle aspiration biopsies predicts survival. Cancer Cytopathol. 2021 11; 129(11):865-873.
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Haye K, Babu S, Oblein L, Gupta R, Akalin A, Escobar-Hoyos LF, Shroyer KR. Keratin 17 Expression Predicts Poor Clinical Outcome in Patients With Advanced Esophageal Squamous Cell Carcinoma. Appl Immunohistochem Mol Morphol. 2021 02 01; 29(2):144-151.
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Bai JDK, Babu S, Roa-Peña L, Hou W, Akalin A, Escobar-Hoyos LF, Shroyer KR. Keratin 17 is a negative prognostic biomarker in high-grade endometrial carcinomas. Hum Pathol. 2019 12; 94:40-50.
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Roa-Peña L, Leiton CV, Babu S, Pan CH, Vanner EA, Akalin A, Bandovic J, Moffitt RA, Shroyer KR, Escobar-Hoyos LF. Keratin 17 identifies the most lethal molecular subtype of pancreatic cancer. Sci Rep. 2019 08 02; 9(1):11239.
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Mockler D, Escobar-Hoyos LF, Akalin A, Romeiser J, Shroyer AL, Shroyer KR. Keratin 17 Is a Prognostic Biomarker in Endocervical Glandular Neoplasia. Am J Clin Pathol. 2017 Sep 01; 148(3):264-273.
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Escobar-Hoyos LF, Shah R, Roa-Peña L, Vanner EA, Najafian N, Banach A, Nielsen E, Al-Khalil R, Akalin A, Talmage D, Shroyer KR. Keratin-17 Promotes p27KIP1 Nuclear Export and Degradation and Offers Potential Prognostic Utility. Cancer Res. 2015 Sep 01; 75(17):3650-62.