Daniel Caffrey received his BSc in Biology and Computer Science from Maynooth University in 1997. He received his PhD from Trinity College Dublin in 2002 where he conducted his research in the laboratories of Professor Denis Shields (RCSI) and Professor Luke O’Neill (TCD). During his PhD studies, he leveraged both computational and experimental methods to study the evolution and function of the MAP kinase pathways in IL1-activated cells. He joined Pfizer in 2002, where he developed various methods to discover and optimize drugs for different gene families. During this period, he was also an adjunct faculty member at Brandeis University and subsequently the chair of the Brandeis Bioinformatics Program from 2008 to 2014. Since joining the University of Massachusetts Medical School in 2010, his research has focused on the use of genomic and computational methods to investigate various aspects of the immune response and host-pathogen interactions.
- The evolution and function of host-virus interactions.
- The structural principles associated with the evolution of host-virus interactions.
- The evolution and function of innate immune genes.
Pfaat (pronounced Pea-fat) was developed to analyze the evolution, structure, and function of proteins.
Complete List of Publications (Google Scholar)