3' Untranslated Regions

"3' Untranslated Regions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The sequence at the 3' end of messenger RNA that does not code for product. This region contains transcription and translation regulating sequences.

Descriptor ID	D020413
MeSH Number(s)	D13.444.735.544.875.880 D13.444.735.790.878.880 G05.360.340.024.220.880.880 G05.360.340.024.340.137.910.880
Concept/Terms	3' Untranslated Regions 3' Untranslated Regions 3'UTR 3'UTRs 3' Untranslated Region Region, 3' Untranslated Regions, 3' Untranslated Untranslated Region, 3' Untranslated Regions, 3' 3' UTR 3' UTRs UTR, 3' UTRs, 3'

Below are MeSH descriptors whose meaning is more general than "3' Untranslated Regions".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleic Acids [D13.444]
RNA [D13.444.735]
RNA, Messenger [D13.444.735.544]
Untranslated Regions [D13.444.735.544.875]
3' Untranslated Regions [D13.444.735.544.875.880]
RNA, Untranslated [D13.444.735.790]
Untranslated Regions [D13.444.735.790.878]
3' Untranslated Regions [D13.444.735.790.878.880]
Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
DNA, Intergenic [G05.360.340.024.220]
Untranslated Regions [G05.360.340.024.220.880]
3' Untranslated Regions [G05.360.340.024.220.880.880]
Genes [G05.360.340.024.340]
Gene Components [G05.360.340.024.340.137]
Untranslated Regions [G05.360.340.024.340.137.910]
3' Untranslated Regions [G05.360.340.024.340.137.910.880]

Below are MeSH descriptors whose meaning is related to "3' Untranslated Regions".

Below are MeSH descriptors whose meaning is more specific than "3' Untranslated Regions".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "3' Untranslated Regions" by people in this website by year, and whether "3' Untranslated Regions" was a major or minor topic of these publications.

Bar chart showing 82 publications over 24 distinct years, with a maximum of 8 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	2	3
2000	0	1	1
2001	0	2	2
2004	1	2	3
2005	0	1	1
2006	1	6	7
2007	0	2	2
2008	0	4	4
2009	0	4	4
2010	0	3	3
2011	1	5	6
2012	1	5	6
2013	1	7	8
2014	2	3	5
2015	1	2	3
2016	0	6	6
2017	1	1	2
2018	0	3	3
2019	0	1	1
2020	0	4	4
2021	1	2	3
2022	0	1	1
2025	1	1	2
2026	1	1	2

Below are the most recent publications written about "3' Untranslated Regions" by people in Profiles.

Nelson C, Ambros V. Multi-dimensional regulation of LIN-28 temporal expression dynamics in the C. elegans heterochronic gene cascade. Development. 2026 May 15; 153(10).

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Varderesian HV, Utaegbulam JN, Brown HE, Ramirez B, Velcani M, Ryder SP. The pos-1 3' untranslated region governs germline specification and proliferation to ensure reproductive robustness. PLoS Genet. 2026 Apr; 22(4):e1012129.

View in: PubMed
Brown HE, Varderesian HV, Lam O, Keane SA, Ryder SP. The mex-3 3' untranslated region is essential for reproduction during temperature stress. Development. 2025 Sep 01; 152(17).

View in: PubMed
Yu T, Blyton MBJ, Abajorga M, Koppetsch BS, Ho S, Xu B, Hu Z, Luban J, Chappell K, Weng Z, Theurkauf WE. Evolution of KoRV-A transcriptional silencing in wild koalas. Cell. 2025 Apr 17; 188(8):2081-2093.e16.

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Eitan C, Siany A, Barkan E, Olender T, van Eijk KR, Moisse M, Farhan SMK, Danino YM, Yanowski E, Marmor-Kollet H, Rivkin N, Yacovzada NS, Hung ST, Cooper-Knock J, Yu CH, Louis C, Masters SL, Kenna KP, van der Spek RAA, Sproviero W, Al Khleifat A, Iacoangeli A, Shatunov A, Jones AR, Elbaz-Alon Y, Cohen Y, Chapnik E, Rothschild D, Weissbrod O, Beck G, Ainbinder E, Ben-Dor S, Werneburg S, Schafer DP, Brown RH, Shaw PJ, Van Damme P, van den Berg LH, Phatnani H, Segal E, Ichida JK, Al-Chalabi A, Veldink JH, Hornstein E. Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3'UTR protect against ALS. Nat Neurosci. 2022 04; 25(4):433-445.

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Griesemer D, Xue JR, Reilly SK, Ulirsch JC, Kukreja K, Davis JR, Kanai M, Yang DK, Butts JC, Guney MH, Luban J, Montgomery SB, Finucane HK, Novina CD, Tewhey R, Sabeti PC. Genome-wide functional screen of 3'UTR variants uncovers causal variants for human disease and evolution. Cell. 2021 09 30; 184(20):5247-5260.e19.

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Albarqi MMY, Ryder SP. The endogenous mex-3 3?UTR is required for germline repression and contributes to optimal fecundity in C. elegans. PLoS Genet. 2021 08; 17(8):e1009775.

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Mangkalaphiban K, He F, Ganesan R, Wu C, Baker R, Jacobson A. Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae. PLoS Genet. 2021 04; 17(4):e1009538.

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Wu C, Roy B, He F, Yan K, Jacobson A. Poly(A)-Binding Protein Regulates the Efficiency of Translation Termination. Cell Rep. 2020 11 17; 33(7):108399.

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Guajardo L, Aguilar R, Bustos FJ, Nardocci G, Guti?rrez RA, van Zundert B, Montecino M. Downregulation of the Polycomb-Associated Methyltransferase Ezh2 during Maturation of Hippocampal Neurons Is Mediated by MicroRNAs Let-7 and miR-124. Int J Mol Sci. 2020 Nov 11; 21(22).

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