"5' Untranslated Regions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The sequence at the 5' end of the messenger RNA that does not code for product. This sequence contains the ribosome binding site and other transcription and translation regulating sequences.
| Descriptor ID |
D020121
|
| MeSH Number(s) |
D13.444.735.544.875.885 D13.444.735.790.878.885 G05.360.340.024.220.880.885 G05.360.340.024.340.137.910.885
|
| Concept/Terms |
5' Untranslated Regions- 5' Untranslated Regions
- 5' Untranslated Region
- Region, 5' Untranslated
- Regions, 5' Untranslated
- Untranslated Region, 5'
- Untranslated Regions, 5'
- 5'UTR
- 5'UTRs
- Leader Sequences, mRNA
- Leader Sequence, mRNA
- Sequence, mRNA Leader
- Sequences, mRNA Leader
- mRNA Leader Sequence
- mRNA Leader Sequences
- 5' UTR
- 5' UTRs
- UTR, 5'
- UTRs, 5'
- Leader mRNA Sequences
- Leader mRNA Sequence
- Sequence, Leader mRNA
- Sequences, Leader mRNA
- mRNA Sequence, Leader
- mRNA Sequences, Leader
|
Below are MeSH descriptors whose meaning is more general than "5' Untranslated Regions".
Below are MeSH descriptors whose meaning is more specific than "5' Untranslated Regions".
This graph shows the total number of publications written about "5' Untranslated Regions" by people in this website by year, and whether "5' Untranslated Regions" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2009 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 1 | 3 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 2 | 2 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "5' Untranslated Regions" by people in Profiles.
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Vora SM, Fontana P, Mao T, Leger V, Zhang Y, Fu TM, Lieberman J, Gehrke L, Shi M, Wang L, Iwasaki A, Wu H. Targeting stem-loop 1 of the SARS-CoV-2 5' UTR to suppress viral translation and Nsp1 evasion. Proc Natl Acad Sci U S A. 2022 03 01; 119(9).
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Blakemore RJ, Burnett C, Swanson C, Kharytonchyk S, Telesnitsky A, Munro JB. Stability and conformation of the dimeric HIV-1 genomic RNA 5'UTR. Biophys J. 2021 11 02; 120(21):4874-4890.
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Ilbay O, Nelson C, Ambros V. C.?elegans LIN-28 controls temporal cell fate progression by regulating LIN-46 expression via the 5' UTR of lin-46 mRNA. Cell Rep. 2021 09 07; 36(10):109670.
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Brigham BS, Kitzrow JP, Reyes JC, Musier-Forsyth K, Munro JB. Intrinsic conformational dynamics of the HIV-1 genomic RNA 5'UTR. Proc Natl Acad Sci U S A. 2019 05 21; 116(21):10372-10381.
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Na CH, Barbhuiya MA, Kim MS, Verbruggen S, Eacker SM, Pletnikova O, Troncoso JC, Halushka MK, Menschaert G, Overall CM, Pandey A. Discovery of noncanonical translation initiation sites through mass spectrometric analysis of protein N termini. Genome Res. 2018 01; 28(1):25-36.
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Protasova MS, Gusev FE, Grigorenko AP, Kuznetsova IL, Rogaev EI, Andreeva TV. Quantitative Analysis of L1-Retrotransposons in Alzheimer's Disease and Aging. Biochemistry (Mosc). 2017 Aug; 82(8):962-971.
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Kalantari P, Harandi OF, Agarwal S, Rus F, Kurt-Jones EA, Fitzgerald KA, Caffrey DR, Golenbock DT. miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN). J Biol Chem. 2017 04 07; 292(14):5634-5644.
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Cenik C, Chua HN, Singh G, Akef A, Snyder MP, Palazzo AF, Moore MJ, Roth FP. A common class of transcripts with 5'-intron depletion, distinct early coding sequence features, and N1-methyladenosine modification. RNA. 2017 03; 23(3):270-283.
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Martinez M, Hinojosa M, Trombly D, Morin V, Stein J, Stein G, Javed A, Gutierrez SE. Transcriptional Auto-Regulation of RUNX1 P1 Promoter. PLoS One. 2016; 11(2):e0149119.
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Kim EZ, Wespiser AR, Caffrey DR. The domain structure and distribution of Alu elements in long noncoding RNAs and mRNAs. RNA. 2016 Feb; 22(2):254-64.