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Seongkyu Yoon PhD

Title
InstitutionUniversity of Massachusetts Lowell
DepartmentChemical Engineering
AddressPerry Hall, Room 310
Lowell, MA 01854
Phone978-934-4741
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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Graham R, Bhatia H, Yoon S. Consequences of trace metal variability and supplementation on CHO cell culture performance: a review of key mechanisms and considerations. Biotechnol Bioeng. 2019 Aug 12. PMID: 31403183.
      View in: PubMed
    2. Cha B, Galbraith SC, Liu H, Park SY, Huang Z, O'Connor T, Lee S, Yoon S. A Thermodynamic Balance Model for Liquid Film Drying Kinetics of a Tablet Film Coating and Drying Process. AAPS PharmSciTech. 2019 Jun 03; 20(5):209. PMID: 31161386.
      View in: PubMed
    3. Behere K, Cha B, Yoon S. Protein a resin lifetime study: Evaluation of protein a resin performance with a model-based approach in continuous capture. Prep Biochem Biotechnol. 2018 Mar 16; 48(3):242-256. PMID: 29355458.
      View in: PubMed
    4. Park SY, Reimonn TM, Agarabi CD, Brorson KA, Yoon S. Metabolic responses and pathway changes of mammalian cells under different culture conditions with media supplementations. Biotechnol Prog. 2018 Feb 21. PMID: 29464928.
      View in: PubMed
    5. Sha S, Bhatia H, Yoon S. An RNA-seq based transcriptomic investigation into the productivity and growth variants with Chinese hamster ovary cells. J Biotechnol. 2018 Apr 10; 271:37-46. PMID: 29476805.
      View in: PubMed
    6. Liu H, Galbraith SC, Park SY, Cha B, Huang Z, Meyer RF, Flamm MH, O'Connor T, Lee S, Yoon S. Assessment of spatial heterogeneity in continuous twin screw wet granulation process using three-compartmental population balance model. Pharm Dev Technol. 2018 Jan 25; 1-13. PMID: 29336653.
      View in: PubMed
    7. Galbraith SC, Liu H, Cha B, Park SY, Huang Z, Yoon S. Modeling and simulation of continuous powder blending applied to a continuous direct compression process. Pharm Dev Technol. 2018 Jan 17; 1-11. PMID: 29304722.
      View in: PubMed
    8. Huang Z, Lee DY, Yoon S. Quantitative intracellular flux modeling and applications in biotherapeutic development and production using CHO cell cultures. Biotechnol Bioeng. 2017 12; 114(12):2717-2728. PMID: 28710856.
      View in: PubMed
    9. Liu H, Galbraith SC, Ricart B, Stanton C, Smith-Goettler B, Verdi L, O'Connor T, Lee S, Yoon S. Optimization of critical quality attributes in continuous twin-screw wet granulation via design space validated with pilot scale experimental data. Int J Pharm. 2017 Jun 15; 525(1):249-263. PMID: 28450171.
      View in: PubMed
    10. Trunfio N, Lee H, Starkey J, Agarabi C, Liu J, Yoon S. Characterization of Mammalian Cell Culture Raw Materials by Combining Spectroscopy and Chemometrics. Biotechnol Prog. 2017 Apr 10. PMID: 28393480.
      View in: PubMed
    11. Bhatia H, Read E, Agarabi C, Brorson K, Lute S, Yoon S. Hybridoma cell-culture and glycan profile dataset at various bioreactor conditions. Data Brief. 2016 Dec; 9:676-678. PMID: 27790631.
      View in: PubMed
    12. Bhatia H, Read E, Agarabi C, Brorson K, Lute S, Yoon S. A design space exploration for control of Critical Quality Attributes of mAb. Int J Pharm. 2016 Oct 15; 512(1):242-52. PMID: 27575657.
      View in: PubMed
    13. Reimonn TM, Park SY, Agarabi CD, Brorson KA, Yoon S. Effect of amino acid supplementation on titer and glycosylation distribution in hybridoma cell cultures-Systems biology-based interpretation using genome-scale metabolic flux balance model and multivariate data analysis. Biotechnol Prog. 2016 Sep; 32(5):1163-1173. PMID: 27452371.
      View in: PubMed
    14. Sha S, Agarabi C, Brorson K, Lee DY, Yoon S. N-Glycosylation Design and Control of Therapeutic Monoclonal Antibodies. Trends Biotechnol. 2016 Oct; 34(10):835-46. PMID: 27016033.
      View in: PubMed
    15. Bhoskar P, Belongia B, Smith R, Yoon S, Carter T, Xu J. Free light chain content in culture media reflects recombinant monoclonal antibody productivity and quality. Biotechnol Prog. 2013 Sep-Oct; 29(5):1131-9. PMID: 23798487.
      View in: PubMed
    16. Kamga MH, Woo Lee H, Liu J, Yoon S. Quantification of protein mixture in chromatographic separation using multi-wavelength UV spectra. Biotechnol Prog. 2013 May-Jun; 29(3):664-71. PMID: 23441030.
      View in: PubMed
    17. Lee HW, Lawton C, Na YJ, Yoon S. Robustness of chemometrics-based feature selection methods in early cancer detection and biomarker discovery. Stat Appl Genet Mol Biol. 2013 May; 12(2):207-23. PMID: 23502343.
      View in: PubMed
    18. Lee HW, Bawn A, Yoon S. Reproducibility, complementary measure of predictability for robustness improvement of multivariate calibration models via variable selections. Anal Chim Acta. 2012 Dec 13; 757:11-8. PMID: 23206391.
      View in: PubMed
    19. Lee HW, Christie A, Xu J, Yoon S. Data fusion-based assessment of raw materials in mammalian cell culture. Biotechnol Bioeng. 2012 Nov; 109(11):2819-28. PMID: 22566239.
      View in: PubMed
    20. Lee HW, Christie A, Liu JJ, Yoon S. Estimation of raw material performance in mammalian cell culture using near infrared spectra combined with chemometrics approaches. Biotechnol Prog. 2012 May-Jun; 28(3):824-32. PMID: 22467629.
      View in: PubMed
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